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Subject-specific, multiscale simulation of electrophysiology: a software pipeline for image-based models and application examples by R.S. MacLeod, J.G.

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Presentation on theme: "Subject-specific, multiscale simulation of electrophysiology: a software pipeline for image-based models and application examples by R.S. MacLeod, J.G."— Presentation transcript:

1 Subject-specific, multiscale simulation of electrophysiology: a software pipeline for image-based models and application examples by R.S. MacLeod, J.G. Stinstra, S. Lew, R.T. Whitaker, D.J. Swenson, M.J. Cole, J. Krüger, D.H. Brooks, and C.R. Johnson Philosophical Transactions A Volume 367(1896):2293-2310 June 13, 2009 ©2009 by The Royal Society

2 Schematic of a simulation pipeline. R.S. MacLeod et al. Phil. Trans. R. Soc. A 2009;367:2293- 2310 ©2009 by The Royal Society

3 Example of volume rendering with ImageVis3D of a torso model based on a high-resolution CT scan (512×512×3172 with a voxel size of 0.51×0.51×0.50 mm, courtesy of Siemens Corporate Research, Princeton). R.S. MacLeod et al. Phil. Trans. R. Soc. A 2009;367:2293- 2310 ©2009 by The Royal Society

4 Example of meshing of the head in a paediatric epilepsy patient. R.S. MacLeod et al. Phil. Trans. R. Soc. A 2009;367:2293- 2310 ©2009 by The Royal Society

5 (a–d) Illustration of simulation of electromagnetic field propagation in a patient-specific brain model. R.S. MacLeod et al. Phil. Trans. R. Soc. A 2009;367:2293- 2310 ©2009 by The Royal Society

6 Whole-heart electrical model of ischaemia with a realistic ischaemic zone. R.S. MacLeod et al. Phil. Trans. R. Soc. A 2009;367:2293- 2310 ©2009 by The Royal Society

7 Pipeline for computing defibrillation potentials in children. R.S. MacLeod et al. Phil. Trans. R. Soc. A 2009;367:2293- 2310 ©2009 by The Royal Society


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