Cortical Structures of the Limbic System Most notable structuresPrimary function Orbitofrontal gyriVery diverse Cingulate gyrusEmotion IsthmusEmotion +

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Presentation transcript:

Cortical Structures of the Limbic System Most notable structuresPrimary function Orbitofrontal gyriVery diverse Cingulate gyrusEmotion IsthmusEmotion + Memory Parahippocampal gyrusMemory UncusOlfaction

Subcortical Structures of the Limbic System Most notable structures: Septal nuclei Nucleus accumbens Mammillary body Amygdala Dorsal thalamus Habenula Hippocampal formation Most notable efferent pathways: Fornix Stria terminalis Ventral amygdalofugal Mammilothalamic

Hippocampal Formation Afferent Pathways Perforant Alvear Fornix Efferent Pathways Fornix

Amygdaloid Complex Afferent Pathways Cingulum Stria Terminalis Lateral oflactory stria Efferent Pathways Stria Terminalis Amygdalofugal

Septal Nuclei & Nucleus Accumbens Septal Pathways MFB (A&E) Stria terminalis (A) Fornix (A&E) Stria medullaris (E) Nuc. Acc. Pathways MFB (A&E) Stria terminals (A) Fornix (A)

Learning and Memory Associative Learning Formation of associations between 2 features in the environment Nonassociative Learning Experience produces changes in the magnitude of the response

Hebb’s Postulate: Cells that fire together wire together; Cells that fire out of sync lose their link Cellular Mechanisms of Memory Long-Term Potentiation Enhancement of synaptic efficacy following strong stimulation

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