Technology Transfer from the University of Oxford An Introduction to Isis, Technology Transfer, and Technology Transfer Consulting WIPO 11th September 2008 Cardiff Dr Roger Welch

Activities Isis Innovation A company owned by the University of Oxford To help researchers commercialise the results of their research Activities Patenting 50 p.a. Licensing of intellectual property 30 p.a. Consulting and service contracts 50 p.a. Formation of new companies 8 p.a. 17

Isis Consulting Business Technology Transfer and Innovation Management Isis Innovation Ltd A company 100% owned by the University of Oxford Oxford Technology Transfer IP, Patents, Licences, Spin-outs, Material Sales, Seed Funds, Isis Angels Network Oxford Expertise Consulting, Services Isis Consulting Business Technology Transfer and Innovation Management

Isis Innovation Staff Managing Director Business Support (7) Tom Hockaday Business Support (7) Head of Group Matt Simons Accounts Gemma Allnutt Marketing Renate Krelle Cynthia Warmington Legal Emma Wheatley Sarah Litchfield Central Admin (5) Office Manager Jenny Bailey Office Administrator Nelson Sa HR Assistant Alex Allan Facilities Jane Tarry Reception Gillian Hicks Technology Transfer Group (25) Head of Group Linda Naylor Oxford University Consulting (6) Head of Group Steve Lee Project Managers Dr Caroline Jenkins Andrew Goff Gurinder Punn Gill Rowe Administrator Kerry Antcliffe Project Manager Teams Dr David Eastham Dr Jamie Ferguson Dr Rakesh Roshan Dr Mike Gilbert Dr Adam Stoten Dr Fiona Begg Dr Sarah Deakin Dr Christine Whyte Dr John Wilson Dr Cynthia Green Dr Erica Conway IAN & Seed Fund Co-ordinator Andrea Alunni Project Manager Teams Dr Mairi Gibbs Dr David Churchman Dr Emma Sceats Dr Stuart Wilkinson Dr Colin Story Dr David Phillips Dr Weng Sie Wong Dr Dina Chen Ya-hsin Shen Patent & Licence Administration Manager Steven Bayliss Post-Deal Admin Ridi Faruque Patent Administrator tba Isis Enterprise (10) Head of Group Dr David Baghurst General Manager Dr Mark Mawhinney Project Managers Dr Sarah Macnaughton Terry Pollard Robert Swerdlow Dr Roger Welch Dr Paul Whyte Dr Suzy Wood Dr Tim Hart Administrator Olivia Thomas OSEM (2) Dr Chris Towler James Mallinson Staff: 56 PhD’s: 28 MBA’s: 12 4

Isis Innovation 2000 - 2008

Who profits from Technology Transfer ? Researchers Technology, royalties and company shares Industry New Technology University Royalties, shares Research Funding from spinouts and licensees Economy New industry and technology to existing ones Investors High returns on world class science

Oxford Model - Key Ingredients Rich portfolio of wholly-owned IPR Strong, world-class research base Diverse research sponsorship (700) Clear intellectual property (IP) policy Led from the top and widely supported Investment in research support & tech transfer 85 staff in Research Services and Isis Innovation Clear internal demarcation of responsibility Effective internal & external communications 12

Intellectual Property Policy (October 2000) University claims ownership of all employees’ and students’ IP rights resulting from University research activities The university assists those researchers who wish to commercialise their research by patenting, licences, spinout companies & consultancy Researchers share the benefits Royalty shares from licences Equity in spinout companies Income from personal consultancy 13 8

Licensing Licensing is when you give someone permission to use your invention in return for: money up front or money when they achieve a defined event or a share of their sales or a share of their profits or A combination of some or all of the above

Royalty Rates Tables are available but With new technology the rate is rarely defined One rule of thumb:“We want a third of your incremental gross profit” So if they make 30% gross on sales we want 10% of sales They do the work so they get 70% Without our idea they don’t get anything

Licensing Pro Con They work you get paid Needs patent protection Can make big money Stimulates research ideas Con Needs patent protection Long time coming Relies on licensee May need proof of concept (resources) They could bury it

Spinouts Pro Most fun You can make most money You still retain some control Con Needs IP protection Needs Investment Needs management Needs a lot of your time Needs a lot of external advice Management Lawyers Etc.

Investors Investors want their money back They want more than they put in They want to know by when They want to know how certain

Investment Sources Oxford University Challenge Seed Fund £4m Launched in 1999 University £1m Treasury, Wellcome, Gatsby £3m Development projects, spin-out seed equity; in a total of 83 projects £4m investment has resulted in Equity stakes in 22 spin-outs, 7 completed licensing deals & 33 active technology projects These 22 spin-outs have attracted £40m seed/venture investment Isis Angels Network Business Angels Seed / Venture Capital Private Equity 100 Members Events No Charges 14

Oxford Spin-outs (pre 2000) * stock exchange listing 15

Oxford Spin-outs (post 2000) Total external investment to date in spin-outs Post 1997: £334m £34m Seed/Business Angels & £300m Venture/Institution Capital * stock exchange listing 16

Begbroke Science & Business Park Prolysis Oxford Gene Technology OxLoc Oxonica Centre for Innovation & Enterprise University Department of Materials Owned & operated by Oxford University University research labs Business Incubator & premises for new companies Central meeting room and café 17

Isis Enterprise Isis Enterprise offers consulting expertise and advice in technology transfer, based upon the success of Isis Innovation as Oxford University’s technology transfer company. Isis Enterprise clients and services: Governments: policy and benchmarking studies Universities and research institutes: policy studies, technology audit, technology transfer office partnerships, training and secondment programmes Companies: out-licensing or in-licensing support, university relationship management open innovation partnerships Professional services firms: market validation studies Investors: investor readiness appraisal www.isis-enterprise.com 18

Isis and The Carbon Trust In December 2006, Isis became a Low Carbon Incubator in partnership with The Carbon Trust. Isis offers support for early stage low carbon projects to anyone in the UK involved in developing low carbon technologies with commercial potential. We work with: Individuals Companies Universities Research Institutes 19

www.isis-innovation.com Sep 08

Executive (policies) Tech transfer office Other academics Gene pool The University Executive (policies) Tech transfer office Gene pool Commercially active scientists Other academics 41

Sub-culture in a barter economy VC’s Lawyers Head hunters PR agents Real estate Leasing Banks Accountants Specialist suppliers Other start-ups Brokers Itinerant managers Consultants Students 42

Contacts Ewert House Ewert Place Summertown Oxford OX2 7SG Isis Innovation Ltd Ewert House Ewert Place Summertown Oxford OX2 7SG T 01865 280830 F 01865 280831 E innovation@isis.ox.ac.uk www.isis-innovation.com Register to receive Isis E-News at www.isis-innovation.com/news/enews 23