23.04.2014 Roberto Carlos Moreno Martín-Bejarano Health and Disease Cancer.

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Starter Activity: Answer the following questions onto a show me board:
Presentation transcript:

Roberto Carlos Moreno Martín-Bejarano Health and Disease Cancer

A) Introduction: Answer the questions of the video. “Animated introduction to Cancer Biology”

A) Hallmarks of cancer:. From the evolutionist point of view cancer follows the principles of natural selection

A) Physiology of cancer. ACCUMULATED MUTATIONS Is the same the iniciating-tumor-cell to the 10th generation cancer cell?

A) Hallmarks of cancer: Angiogenesis Why cancer cell spread to other parts of the body?

A) Hallmarks of cancer: Anti-angiogenic therapy

B) Hallmarks of cancer: Metástasis

B) Hallmarks of cancer: Metástasis. DIAGNOSIS

Mutacion Expansion Apoptosis Defectos en vias de senescencia o apoptosis Escape de senescencia Nuevas mutaciones Tumor maligno Tumor benigno Senescencia Apoptosis Respuesta antiproliferativa inmediata Lesion Senescencia Stem Cell B) Hallmarks of cancer: Senescencia

B) Cancer Stem Cells

B) Cancer Stem cells: 2 factors: Genetic mutations

B) Cancer Stem cells: 2 factors: Level of mutations + -

Kidney for Katie: ROL PLAY

D) OUR INVESTIGATION: