Publishing Bioinformatics in a Well Established Biology Program Conference on Linking Mathematics and Biology in the High Schools Linda Lundgren Author of Biology the Dynamics of Life

Bioinformatics: Analyzing electronically stored biological data using computer-based tools

Why should bioinformatics become part of a mainstream biology program? National and State standards Mathematics is important in biology Real-world applications of biology A well established biology program will bring this concept to the most students and teachers

How and where would bioinformatics fit into the Glencoe McGraw-Hill biology program?

What determines the Activities and Content in a biology book? National and State Standards –General standards –Content standards State and Local Standardized Testing –Test practice, Intervention, Remediation Market Research Research Based Practices Competitive Analysis “No Child Left Behind” mandate –Enrichment -- Inclusion -- Remediation More…

What determines the Activities and Content in a biology book? (cont.) Student Friendly Materials –Reading strategies –Readability Inquiry Approach –Students explore and analyze actual data in a way that recreates the experience of conducting research Staff Development Lab Component Technology –Virtual Labs –Website More…

Student Edition Prescreened Web links bdol.glencoe.com Standardized Test Practice Self-check quizzes/tests Biology career info Vocab PuzzleMaker In The News WebQuest interactive projects Interactive Tutor Internet BioLabs Microscopy Links Textbook updates Teacher Bulletin Board Web Site

 Investigate BioLabs  MiniLabs  Design Your Own Labs  Problem-Solving Labs  Internet Labs  Alternate Labs  CBL Labs  Science Inquiry Labs  Forensics & Biotech Labs  Virtual Labs  Video Labs LAB Component

LAB Component In the Text Book:

Lab Manuals: LAB Component Pre AP Lab Manual

National and State Standards Related to Bioinformatics Standards Science as inquiry Measurement Use of technology Examples from State Standards: FL: “computer simulations”, “use of analytic skills” OH: “design and conduct experiments” NY: “use mathematical analysis”, “develop mathematical formulations to represent one’s thinking” NC: students use “knowledge and skills of technological design”, “analyze data” IL: “apply statistical methods to data to reach and support conclusions” PA: “apply knowledge and understanding about the nature of scientific and technological knowledge” GA: “students will demonstrate the computation and estimation skills necessary for analyzing data…”

Biological Databases currently available for study and analysis: World’s species with conservation concerns Protected areas World’s forests Marine statistics Biological diversity DNA and protein

Real World Biological Problems that lend themselves to mathematical analysis: Predicting infectious disease epidemics Managing natural resources Forecasting the effects of global climate change Evaluating the movement of agricultural pests Determining the size and spatial configuration of marine reserves needed to sustain an overexploited fish population Calculating effects of spreading of alleles from genetically modified organisms Analyzing genetic data Describing complex cellular networks such as networks of signaling proteins Predicting biodiversity

Where would bioinformatics fit into a mainstream biology program? In the Textbook?In a Manual?In Technology? MiniLab Problem Solving Lab Internet Lab Design Your Own Lab Lab Manual Inquiry Lab Manual Forensics Lab Manual Pre AP Lab Manual Website Virtual Lab CD