Genetic genealogy and East Asian print collections Ken Klein University of Southern California March 30, 2011.

Slides:



Advertisements
Similar presentations
A family history of a genetic condition or trait
Advertisements

Population Genetics 3 We can learn a lot about the origins and movements of populations from genetics Did all modern humans come from Africa? Are we derived.
Kinship and Descent. Chapter Outline  What are descent groups?  What functions do descent groups serve?  How do descent groups evolve?
M242 M60 M91 M130 M96 M201 M168 M52 M89 M170M304 M9 M175 M45 M173 The final lineage to arise from the Y-chromosome tree appeared about 15,000 years ago.
CLOUD Surname DNA Project. Genetic Genealogy A Report on The CLOUD DNA Project. 1.Our Data Examined 2.Intro to Genetic Genealogy & DNA Genealogical.
Genetic Genealogy A Report on The CLOUD DNA Project. 1.Our Data Examined 2.Intro to Genetic Genealogy & DNA Genealogical DNA and its Components 4.Examining.
Genetic Genealogy A Report on The CLOUD DNA Project. 1.Our Data Examined 2.Intro to Genetic Genealogy & DNA Genealogical DNA and its Components 4.Examining.
CLOUD Surname DNA Project. Genetic Genealogy A Report on The CLOUD DNA Project. 1.Our Data Examined 2.Intro to Genetic Genealogy & DNA Genealogical.
Fischer/Genetic Genealogy Fischer Family Reunion July 27 to July 29, 2012 Lebanon, CT Presented by Craig Fischer Questions to
1 ANCIENT AND MODERN DNA IN THE AMERICAS: IMPLICATIONS FOR THE PEOPLING OF THE NEW WORLD Frederika A. Kaestle, Ripan S. Malhi, Jason A. Eshleman, David.
45,000 BC M89 As the Out of Africa lineage migrated across northeastern Africa and the Arabian Peninsula another mutation occurred on the Y-chromosome.
Introduction to Genetics. Fact or Fiction? Man is the highest of the animals; therefore, he has the most chromosomes. FALSE.
Genetics & Heredity.
Lineage and Descent ANTH 321: Kinship and Social Organization Kimberly Martin,Ph.D.
Chapter 9 Kinship and Descent. Chapter Outline  Why Study Kinship?  Unilineal Descent  Cognatic Descent  Bilateral Kinship  Influences on Kinship.
September  Determine genetic lineages  Find the Peter Worden genetic signature  Help break down brick walls  Align descendants with sons of.
 WFGS. 23andMeby Jerry Merritt   Explain the problems with Autosomal DNA tests.  Provide a tour of a 23andMe autosomal account.  Show how to handle.
Creation and Evolution. The 3 Basic Theories Creation Evolution Intelligent Design.
DNA in Genealogy R.E. Butler Apr 9/2005. Presentation Outline No. Slides DNA Basics4 DNA Testing for Genealogy7 Sample Results & Maps5 Sample Data Base.
Genealogy and DNA. Genetic Genealogy  Began around 2003 Growing availability of testing Growing affordability of testing  Genographic Project Anthropological.
How old am I? Office Hours Bonuses. 1.7 million-year-old human ancestor.
The ADSHEAD DNA Project What can it do for us ?. DNA Summary Some Issues Some Possible Targets Quick look at a bit of Technology.
F AMILIES, K INSHIP, & D ESCENT Chapter 10. N UCLEAR F AMILY Term nuclear is used in its general meaning referring to a central entity or "nucleus" around.
Kinship and Descent Chapter 10. What Is Kinship? Kinship is a social network of relatives within which individuals have rights and obligations. Kinship.
Chapter Twelve. Section One A. The family is the most universal social institution B. Definition varies from culture to culture.
The Tree of Life. Questions 6.5 Billion Humans 6.5 Billion Humans Who were the first modern people in Africa? Who were the first modern people in Africa?
The Human Genographic Project Presentation By: Daniel Zirkel, Leila Beheshti and Nicole Scagliola Lab Performed By: Chris Seiter, Lindsay Cafiero, & Jerry.
The Search for Genetic Eve and Adam. Divergence Points 5-7 Million Years Ago (MYA)– Divergence from the Chimpanzee Lineage 5-7 Million Years Ago (MYA)–
The Family.
The Family Chapter 12.
Evolution within a species Aims: Must be able to state the observations and subsequent deductions that Darwin and Wallace based their theories on. Should.
KEY CONCEPT Molecular clocks provide clues to evolutionary history.
A family history of a genetic condition
PEDIGREE CHARTS A family history of a genetic condition.
Understanding DNA and DNA Testing
How old am I? Exam #1 F 2/13 Bonuses posted. 1.7 million-year-old human ancestor.
Pedigrees.
Lesson 9: Marriage and the Family
Human Genetic Pedigrees. What is a Genetic Pedigree? l A genetic pedigree is an easy way to track your family traits. It looks like a family tree, but.
Copyright © 2010 Pearson Education, Inc. publishing as Benjamin Cummings Lectures by Greg Podgorski, Utah State University Current Issues in Biology, Volume.
By Regina Carr. DNA Ancestors Parents Children Grandchildren Great Grandchildren Types of Families Conclusion.
What is Genetics? Genetics is the scientific study of heredity.
Post-Darwinian Facts I. Physics II. Geology/Paleontology III. Genetics.
Kinship and Descent Genealogical Space – Space that contains all human beings. Kinship and descent are Cultural Universals.
Chapter 10, Kinship Key Terms. Kinship Culturally defined relationship established on the basis of blood ties or through marriage. Consanguineal Related.
DNA and Surname Studies
Summary of chromosome characteristics Diploid set for humans; 2n = 46 Autosomes; homologous chromosomes, one from each parent (humans = 22 sets of 2) Sex.
Human Mitochondrial Molecular Biology Center for Advanced Studies at Wheeler High School Post-AP DNA/Genetics.
DNA types: Division on the basis of position Chromosomal DNA Present on chromosome and is always part of choromosomal inheritance. It contains two nuclear.
Molecular Clocks and Evolution Bio 135 Summer 2009.
The Little BIG HISTORY of Human Migration The Horn of Africa, 80,000 BC: Have you ever wondered what routes our ancestors took as they multiplied and settled.
Bring your cheat sheet Exam #1 F 2/12 Q&A Th 2/11 from 5-7pm in PAI million-year- old human ancestor.
The Human Chromosomes 1. Other Structural Variants Inversion DeletionCopy number variant.
HW: Copy the Kinship symbols and kin type association for your notes
KEY CONCEPT Molecular clocks provide clues to evolutionary history.
Ancestry and mtDNA, Mitochondrial Eve and Y Chromosome Adam
DNA as a Tool in Your Family Research Toolkit
PCR Machine.
KEY CONCEPT Molecular clocks provide clues to evolutionary history.
KEY CONCEPT Molecular clocks provide clues to evolutionary history.
The Earliest Humans © Student Handouts, Inc..
The Earliest Humans © Student Handouts, Inc..
The transmission of traits from one generation to the next is called inheritance, or heredity.
The Earliest Humans © Student Handouts, Inc..
A Populationwide Coalescent Analysis of Icelandic Matrilineal and Patrilineal Genealogies: Evidence for a Faster Evolutionary Rate of mtDNA Lineages than.
FAMILY TIES.
Families, Kinship, & Descent
Complete the following sentences with the name of the relative.
Bonus #1 is due today at 5pm by
Inquiry 2 Reports due this week
Presentation transcript:

Genetic genealogy and East Asian print collections Ken Klein University of Southern California March 30, 2011

Y-chromosome and mitochondria DNA Autosomes: recombination of chromosome strands from both parents Non-combinant DNA which is passed from generation to generation with virtually no alteration. 1.Y-DNA, passed from father to son, unaltered by DNA from the mother. 2.mtDNA, passed through the maternal line, mother to daughter, unaltered.

Y-DNA and mtDNA as genealogical tools Both are passed unaltered but with a predictable rate of mutation y-DNA and the written and published record in East Asian societies.

Stix, Gary, “Traces of a Distant Past,” Scientific American 299:1 (January 2008): 59.

Pointing out some obvious facts We receive our DNA, our genetic code from two parents.

Two generations back, we trace our DNA back to four grandparents.

Five generations back, each of us has 32 direct ancestors …

_______________ And that number doubles again for each additional generation we trace back.

Twenty-five generations back, each of us has 33,554,532 (2^25) statistical ancestors. This is not say, however, that there are that many different ancestors.

The case of the 楊 Yeung (Yang) lineage of 中山 Zhongshan (formerly 香山 Xiangshan), Guangdong Province 南雄 香山

Three genealogical sources for the Xiangshan Yeung’s 楊家譜. 25 generations of descent from 楊大章, the youngest of four brothers in the 3 rd generation, down to 20 th century. (photocopy of original manuscript record) 楊氏族譜 Published record (1848; 1877; 1933) of 23 generations of patrilineal descent from 楊大刚, the eldest of the four brothers in the 3 rd generation, but only fully articulated from the 19th to the 23 rd generation. 楊家譜. 6 generation manuscript of descent from 楊明組, 16 th generation descendant in another line.

楊氏族譜 (1933)

Yeung marriage partners, 楊明組 and 楊大章 lines Total marriages Jeng 鄭 Wong 黃 Next highest 楊明組 123 (25%)4 (33%)1 (8%) 楊大章 (15%)12 (11%)8 (7%) 楊大章 (lineage of 25) 226 (27%)4 (18%)2 (9%)

Yeung marriage partners 楊大刚 line Total marriages Tam 譚 Cheng 程 Next highest 楊元規 (15.2%)23 (11.0%)16 (7.4%) (Jeng 鄭 and Wong 黃 marriages constituted 4.6% and 1.8% of the total)

The 25 th generation descendant has a Jeng female ancestor in the 5 th, 7 th, 10 th, 12 th, 15 th, & 20 th generations (red). And a Wong female ancestor in the 2 nd, 19 th, 21 st, & 22 nd generations (yellow)

If Wong wife (22G) was a great-great granddaughter of the father of Wong wife (19G), there would be an overlap of statistical ancestors 25 generations back in the amount of 2^18 (262,144)—for just that one repeat appearance in the family tree. If, on top of that, Wong wife (21G) was the granddaughter of the brother of Wong wife (19G), there would be another overlap of statistical ancestors of the same size.

Replicated several times over, this helps to illustrate that, among the the 33+ million statistical ancestors a 25 th generation Xiangshan Yeung has, some individuals— many individuals—will appear multiple times. The actual number of ancestors 25 generations back is likely quite limited.

From this perspective, we can view a 25 generation genealogy as consisting not so much of 33+ million individuals but of a skein of lineages that intersect repeatedly in complex fashion.

Here’s where I finally get back to genetic genealogy.

中山石岐杨氏 Zhongshan Shiqi Yang Lineage : Haplogroup L Originated in Southwest Asia approximately 18,000 years ago.

So what use is the DNA test? o Verification of patrilines o Genetic profile of a locality o Comparability with other localities o Asian American issues o Help to sort out paper son thickets

中山石岐杨 / 邓 / 林 Zhongshan Shiqi Yang/Deng/Lin Maternal Haplogroup M (“Seafarers”) Originated in area between East Africa and Persian Gulf approximately 65,000 years ago.