4 A Tour of the Cell Brad Stith, University of Colorado Denver

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Presentation transcript:

4 A Tour of the Cell Brad Stith, University of Colorado Denver 4 A Tour of the Cell Questions prepared by Brad Stith, University of Colorado Denver Jung Choi, Georgia Institute of Technology

Which cellular structure is common to all three domains of life? nucleus endoplasmic reticulum mitochondria phospholipid bilayer cell membrane endocytotic vesicles Answer: D

Which cellular structure is common to all three domains of life? nucleus endoplasmic reticulum mitochondria phospholipid bilayer cell membrane endocytotic vesicles 3

endoplasmic reticulum nucleus lysosomes Golgi plasma membrane Enzymes responsible for biosynthesis of membrane lipids would be located in what part of the cell? endoplasmic reticulum nucleus lysosomes Golgi plasma membrane Answer: A This question focuses on Concept 4.4. 4

endoplasmic reticulum nucleus lysosomes Golgi plasma membrane Enzymes responsible for biosynthesis of membrane lipids would be located in what part of the cell? endoplasmic reticulum nucleus lysosomes Golgi plasma membrane 5

Mitochondria and chloroplasts have double membranes. Which of the following is not an argument for the theory that mitochondria and chloroplasts evolved from prokaryotic endosymbionts? Mitochondria and chloroplasts have double membranes. Mitochondria and chloroplasts have their own ribosomes. Mitochondria and chloroplasts have their own DNA. The mitochondrial and chloroplast genomes are circular. All of the above support the endosymbiotic theory. Answer: E This question focuses on Concept 4.5. 6

Mitochondria and chloroplasts have double membranes. Which of the following is not an argument for the theory that mitochondria and chloroplasts evolved from prokaryotic endosymbionts? Mitochondria and chloroplasts have double membranes. Mitochondria and chloroplasts have their own ribosomes. Mitochondria and chloroplasts have their own DNA. The mitochondrial and chloroplast genomes are circular. All of the above support the endosymbiotic theory. 7

Autophagy removes old damaged organelles like mitochondria Autophagy removes old damaged organelles like mitochondria. Decreased autophagy results in degeneration and inflammation and may result in the “symptoms” of aging. Which of the following organelle(s) is/are central to autophagy? smooth ER peroxisomes rough ER lysosomes Golgi apparatus Answer: D This question covers a hot area of research and involves application of information on lysosomes. 8

Autophagy removes old damaged organelles like mitochondria Autophagy removes old damaged organelles like mitochondria. Decreased autophagy results in degeneration and inflammation and may result in the “symptoms” of aging. Which of the following organelle(s) is/are central to autophagy? smooth ER peroxisomes rough ER lysosomes Golgi apparatus 9

What is the correct order of the exocytosis or secretion pathway? rough ER, endosome, Golgi, smooth ER rough ER, Golgi, smooth ER, exocytosis smooth ER, rough ER, exocytosis, Golgi rough ER, Golgi, transport vesicle, exocytosis rough ER, Golgi, endosome, exocytosis, transport vesicle Answer: D 10

What is the correct order of the exocytosis or secretion pathway? rough ER, endosome, Golgi, smooth ER rough ER, Golgi, smooth ER, exocytosis smooth ER, rough ER, exocytosis, Golgi rough ER, Golgi, transport vesicle, exocytosis rough ER, Golgi, endosome, exocytosis, transport vesicle 11

lysosomes, transport vesicles, plasma membrane Brefeldin A is a drug that disrupts transport from the ER to the Golgi apparatus. What other organelles and membranes are affected? lysosomes, transport vesicles, plasma membrane mitochondria, peroxisomes, plasma membrane vacuoles, mitochondria, plasma membrane lysosomes, transport vesicles, nuclear membrane all intracellular organelles and membranes Answer: A This question corresponds with Concept 4.4. It addresses student understanding of membrane flow and the continuity of the endomembrane system. 12

lysosomes, transport vesicles, plasma membrane Brefeldin A is a drug that disrupts transport from the ER to the Golgi apparatus. What other organelles and membranes are affected? lysosomes, transport vesicles, plasma membrane mitochondria, peroxisomes, plasma membrane vacuoles, mitochondria, plasma membrane lysosomes, transport vesicles, nuclear membrane all intracellular organelles and membranes 13

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