The Wealth of Innovation Israel Life Science Industry February 2010

Mission Promote Trade, Joint Ventures and Strategic Alliances between overseas and Israeli Companies. Promote Trade, Joint Ventures and Strategic Alliances between overseas and Israeli Companies. Endorse the integration of Israeli companies into the global market. Endorse the integration of Israeli companies into the global market.Goal Facilitate Business Opportunities Facilitate Business Opportunities The IEICI Your Link to the Industry

Israel and Neighbours Necessity is the Mother of Inventions

Israel at a Glance Area: 21,000 km 2 Population: 7.46 Million GDP/Capita: $27,220 Total Export: $80.4 Billion (13%) Export of Goods: $56.5 Billion (14.4%) 5 years average Inflation rate: 1.6% Penetration [House hold]: Mobile - 98% Fast Internet - 72% [39 H/month]

Global Competitiveness Israel In the global competitiveness index Israel is ranked 23/134 Notable AdvantagesRank Quality of scientific research institutions3 Utility patents5 VC availability8 Source: World Economic Forum ( )

Creation Creativity from Creation to Creativity Israel Life Science Industry

Science & Novelty Nobel Prize Winners Prof. Avram Hershko & Prof. Aaron Ciechanover Winner of the 2004 Nobel Prize in Chemistry Total of 9 Nobel Prize winners in Economy (2005, 2002), Literature (1966) and in Peace (1978,1994). Prof. Ada Yonath Winner of the 2009 Nobel Prize in Chemistry

The Industry Drivers 1. Technology Transfer Institutes 2. Commercialized defense technology 3. Healthcare system 4. Strong entrepreneurial spirit 5. Powerful VC community 6. Highly skilled workforce 7. Institutional incentives

Well of Novelty Creative fusion between academia and business Basic Research Clinical Trials Teva Licensing FDA Approval

Fountain of Innovation and they shall beat their swords into plowshares… Given Imaging Galil Medical Remon Medical MTC Industries

Spring of Creativity Early adopters physician Healthcare expenditure 2008 Healthcare expenditure % of the GDP, (2,088$ per capita) 8% of the GDP, (2,088$ per capita) 3.5 Physicians per Physicians per general hospitals (373 hospitals), 42,100 beds 44 general hospitals (373 hospitals), 42,100 beds Sources: CBS Israel

Culture Strong Entrepreneurial Spirit. Strong Entrepreneurial Spirit. Improvisation - Risk taking attitude. Improvisation - Risk taking attitude. Military service based - Intense social networking. Military service based - Intense social networking. Convergence - Different socio-economy background Convergence - Different socio-economy background Informality - Easy access to decision makers. Informality - Easy access to decision makers. Extensive new immigrants - Multicultural environment. Extensive new immigrants - Multicultural environment. Medinol Gregory Pinchasik

Private VC Industry Government Fund $100 Million 2008 ~80 Private VC Funds $10 Billion PontifaxArteAurum companies raised $2.08 b, 18% above the $1.76 b raised in 2007 and 28% above 2006.

Highly Skilled Workforce 34% of the population holds university degrees. 34% of the population holds university degrees. 24% of the working force (3 rd after the US and Holland). 24% of the working force (3 rd after the US and Holland). 12% holds advanced degree 12% holds advanced degree 40% of the 90s immigrants hold academic degree. 40% of the 90s immigrants hold academic degree.

Institutional Incentives Chief Scientists grants Chief Scientists grants R&D Consortiums R&D Consortiums Technology incubators Technology incubators Bi-National funds Bi-National funds Federal grants (NIH) Federal grants (NIH) EU Framework EU Framework Marketing Grants Marketing Grants Expenditure of civilian R&D In Israel & OECD countries (% of GDP) Graduated 1,175 (100%) No Funds 463 (39%) Active 51 (4.4%) Ceased 412 (34.6%) Raised Funds 712 (61%) Ceased 318 (27.5%) Active 394 (33.6%)

Israel Life Science Industry Business Card

Fast Growing Industry Young, Creative, & Innovative Industry 1996By companies over 1000 companies new companies being formed each year

Growth Engine Export - $6.5 billion in 2008 (26%) Export - $6.5 billion in 2008 (26%) 13% of the goods export (38% of High-Tech) 13% of the goods export (38% of High-Tech) NA 72%, Europe 21%, and Asia 5%. NA 72%, Europe 21%, and Asia 5%.

Medical Devices Ranked 2 nd for its Medical Devices Solutions TopSpin Medical TopSpin Medical Intravascular MRI Insightec MRI Guided non-invasive surgical procedure X Sirius IS Sirius IS Perpetumobila

Molecules - Bio & Pharma A World Leader in Research Smart Biotech Time traveling: up-to Smart Biotech Time traveling: up-to 2 years in 5 days BiondVax BiondVax Multi-season/multi-strain Flu vaccine Protalix [AMEX: PLX] Protalix [AMEX: PLX] Plant cell-based recombinant protein expression technology

Healthcare IT Leading in Implementations Over 95% of MDs use IT in daily practice. Israel is among the world leaders in the usage of Information Technology (IT) in Healthcare (Gartner)

Wealth of Clusters A Short List Diagnostics (125) Diagnostics (125) Healthcare IT (73) Healthcare IT (73) Imaging (62) Imaging (62) Drug Delivery (54) Drug Delivery (54) MIS (49) MIS (49) Monitoring (39) Monitoring (39) Telemedicine (15) Telemedicine (15) Cardiovascular (106) Cardiovascular (106) Dental (69) Dental (69) Derma &Aesthetics (40) Derma &Aesthetics (40) Oncology (38) Oncology (38) Orthopedics (32) Orthopedics (32) Women's Health (31) Women's Health (31) Home Care Home Care

Israel Life Science Industry Bringing Innovation Around the World

International Presence With Equity Position

Knowledgebase Portal Intuitive Map & Smart Search

Israel The Promised Land 15 May , ,465,000

Thanks Choose Israel Let us do the rest Angelica Khachaturov Medical Devices & Healthcare IT Ronen Gruber Biotechnology & Pharmaceuticals Industries