2,3-Butanedione monoxime cardioplegia: advantages over hyperkalemia in blood- perfused isolated hearts A.Mark Jayawant, MD, Edward R. Stephenson, MD,

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Presentation transcript:

2,3-Butanedione monoxime cardioplegia: advantages over hyperkalemia in blood- perfused isolated hearts A.Mark Jayawant, MD, Edward R. Stephenson, MD, Ralph J. Damiano, MD The Annals of Thoracic Surgery Volume 67, Issue 3, Pages 618-623 (March 1999) DOI: 10.1016/S0003-4975(98)01273-9

Fig 1 Postreperfusion systolic function, as assessed by percent recovery of developed pressure (%DP). Results are expressed as means plus or minus standard error of the mean. ∗p < 0.05 versus control. (BDM = 2,3-butanedione monoxime; CONTROL = no cardioplegia; StT = St. Thomas’ solution.) The Annals of Thoracic Surgery 1999 67, 618-623DOI: (10.1016/S0003-4975(98)01273-9)

Fig 2 Effect of no cardioplegia (CONTROL), St. Thomas’ solution (StT), and 2,3-butanedione monoxime (BDM) cardioplegia on postreperfusion myocardial tissue water content (%H2O). Results are expressed as means plus or minus standard error of the mean. ∗p < 0.05 versus control and StT. The Annals of Thoracic Surgery 1999 67, 618-623DOI: (10.1016/S0003-4975(98)01273-9)

Fig 3 Coronary blood flow (CBF) under preischemic conditions (time = 0 min) and effect of no cardioplegia (CONTROL), St. Thomas’ solution (ST. THOMAS’ SOLN), and 2,3-butanedione monoxime (BDM) cardioplegia on CBF during the reperfusion period (time = 60 to 90 min). Results are expressed as means plus or minus standard error of the mean. ∗p < 0.05 versus preischemic CBF. The Annals of Thoracic Surgery 1999 67, 618-623DOI: (10.1016/S0003-4975(98)01273-9)