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Inhibition of inducible nitric oxide synthase after myocardial ischemia increases coronary flow  Patrick E Parrino, MD, Victor E Laubach, PhD, John R.

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Presentation on theme: "Inhibition of inducible nitric oxide synthase after myocardial ischemia increases coronary flow  Patrick E Parrino, MD, Victor E Laubach, PhD, John R."— Presentation transcript:

1 Inhibition of inducible nitric oxide synthase after myocardial ischemia increases coronary flow 
Patrick E Parrino, MD, Victor E Laubach, PhD, John R Gaughen, BA, Kimberly S Shockey, MS, Terri-Ann Wattsman, MD, Robert C King, MD, Curtis G Tribble, MD, Irving L Kron, MD  The Annals of Thoracic Surgery  Volume 66, Issue 3, Pages (September 1998) DOI: /S (98)

2 Fig 1 Schematic of the isolated, blood-perfused heart circuit. (Vent = ventilator.) The Annals of Thoracic Surgery  , DOI: ( /S (98) )

3 Fig 2 Coronary flow during postintervention perfusion. (L-NAME = Nω-nitro-l-arginine methyl ester; LD 1400W = low-dose 1400W; HD 1400W = high-dose 1400W; Non I 1400W = nonischemic 1400W; Non I Control = nonischemic control.) The Annals of Thoracic Surgery  , DOI: ( /S (98) )

4 Fig 3 Left ventricular developed pressure during postintervention perfusion. (L-NAME = Nω-nitro-l-arginine methyl ester; LD 1400W = low-dose 1400W; HD 1400W = high-dose 1400W; Non I 1400W = nonischemic 1400W; Non I Control = nonischemic control.) The Annals of Thoracic Surgery  , DOI: ( /S (98) )

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