Effect of cysteamine. Effect of cysteamine. (A) Comparative inhibitory effect of Vnn1 transfection versus cysteamine (CEA) administration (120 mg/kg i.p.) on tumor growth in nude mice. For clarity, results are normalized by showing the percentage of growth inhibition comparing VR versus R (VR/R) and CEA-treated versus CEA-untreated R (R CEA/R) tumor growth. (B, C) Effect of cysteamine (CEA) administration on the expression of transcripts associated with hypoxia (B) or differentiation (C). Caroline Giessner et al. LSA 2018;1:e201800073 © 2018 Naquet et al.