Presentation is loading. Please wait.

Presentation is loading. Please wait.

(A) ZR75-1 cells were treated with 1 μM 5-aza-2′-deoxycytidine (5-Aza) for 4 d. (A) ZR75-1 cells were treated with 1 μM 5-aza-2′-deoxycytidine (5-Aza)

Published byMaximilian Burns Modified over 5 years ago

Similar presentations

Presentation on theme: "(A) ZR75-1 cells were treated with 1 μM 5-aza-2′-deoxycytidine (5-Aza) for 4 d. (A) ZR75-1 cells were treated with 1 μM 5-aza-2′-deoxycytidine (5-Aza)"— Presentation transcript:

1 (A) ZR75-1 cells were treated with 1 μM 5-aza-2′-deoxycytidine (5-Aza) for 4 d.
(A) ZR75-1 cells were treated with 1 μM 5-aza-2′-deoxycytidine (5-Aza) for 4 d. PPARG and LPL mRNA levels were analyzed by RT-qPCR; mean ± SD of two technical replicates. (B) Scatter plot depicting PPARG and LATS1 mRNA expression levels in luminal tumors (TCGA BRCA dataset, n = 613). (C) ZR75-1 cells were transfected with either control vector (GFP only) or GFP-LATS2 expression plasmid and treated with 100 μM RGZ for 4 d. Cell death was measured as in Fig 3D. Values were normalized relative to nontreated cells transfected with vector only. (D) ZR75-1 cells were transfected with the indicated siRNA oligonucleotides and treated with 100 μM RGZ for 4 d. The percentage of dead cells was measured by PI exclusion followed by flow cytometry analysis, and values were normalized to nontreated siControl cells. Noa Furth et al. LSA 2018;1:e © 2018 Furth et al.

Download ppt "(A) ZR75-1 cells were treated with 1 μM 5-aza-2′-deoxycytidine (5-Aza) for 4 d. (A) ZR75-1 cells were treated with 1 μM 5-aza-2′-deoxycytidine (5-Aza)"

Similar presentations

B Supplementary Fig S1. (A) ZR75- and MCF7-PELP1 knockdown cells were generated as described in methods section. Pooled colonies were analyzed for PELP1.

B Supplementary Fig S1. (A) ZR75- and MCF7-PELP1 knockdown cells were generated as described in methods section. Pooled colonies were analyzed for PELP1.
Cell Physiol Biochem 2013;32: DOI: /

Cell Physiol Biochem 2013;32: DOI: /
From: MicroRNA let-7 Regulates 3T3-L1 Adipogenesis

From: MicroRNA let-7 Regulates 3T3-L1 Adipogenesis
Rab11-FIP3 silencing impairs T cell activation events.

Rab11-FIP3 silencing impairs T cell activation events.
Rab11-FIP3 silencing upregulates TCR-CD3 cell surface expression in an Lck-dependent manner. Rab11-FIP3 silencing upregulates TCR-CD3 cell surface expression.

Rab11-FIP3 silencing upregulates TCR-CD3 cell surface expression in an Lck-dependent manner. Rab11-FIP3 silencing upregulates TCR-CD3 cell surface expression.
An siRNA screen identifies LIMT as an ERK‐dependent negative regulator of mammary cell migration An siRNA screen identifies LIMT as an ERK‐dependent negative.

An siRNA screen identifies LIMT as an ERK‐dependent negative regulator of mammary cell migration An siRNA screen identifies LIMT as an ERK‐dependent negative.
Expression of α5β1-integrin enhances EboV GP-mediated infection of GD25 cells. Expression of α5β1-integrin enhances EboV GP-mediated infection of GD25.

Expression of α5β1-integrin enhances EboV GP-mediated infection of GD25 cells. Expression of α5β1-integrin enhances EboV GP-mediated infection of GD25.
NF1 silencing confers resistance of PC9 lung adenocarcinoma cells to erlotinib (erl). NF1 silencing confers resistance of PC9 lung adenocarcinoma cells.

NF1 silencing confers resistance of PC9 lung adenocarcinoma cells to erlotinib (erl). NF1 silencing confers resistance of PC9 lung adenocarcinoma cells.
PPARγ signaling correlates with LATS2 in human and mouse tumors and promotes cell death in a LATS2-dependent manner. PPARγ signaling correlates with LATS2.

PPARγ signaling correlates with LATS2 in human and mouse tumors and promotes cell death in a LATS2-dependent manner. PPARγ signaling correlates with LATS2.
BRD4 is associated with poor patient survival and constitutes a promising target for NRASMut melanoma BRD4 is associated with poor patient survival and.

BRD4 is associated with poor patient survival and constitutes a promising target for NRASMut melanoma BRD4 is associated with poor patient survival and.
A B 20% O2 5% O2 C 5% O2 + NAC DAPI gH2AX pLKO.1 GFP-SOD1 S 0.1Gy

A B 20% O2 5% O2 C 5% O2 + NAC DAPI gH2AX pLKO.1 GFP-SOD1 S 0.1Gy
Expression and regulation of MD-2s.

Expression and regulation of MD-2s.
DNAPKcs is required for DNA repair in the presence of androgen.

DNAPKcs is required for DNA repair in the presence of androgen.
LATS2 is a tumor suppressor in a mouse lumB breast cancer model.

LATS2 is a tumor suppressor in a mouse lumB breast cancer model.
(A) Schematic representation of the conditional Lats1 locus.

(A) Schematic representation of the conditional Lats1 locus.
B7-H4 expression correlates with MHC-I expression and improved prognosis in patients with breast cancer. B7-H4 expression correlates with MHC-I expression.

B7-H4 expression correlates with MHC-I expression and improved prognosis in patients with breast cancer. B7-H4 expression correlates with MHC-I expression.
Expression of SYCE2 activates the DSB repair pathway.

Expression of SYCE2 activates the DSB repair pathway.
Deletion of Lats1 is phenotypically distinct from Lats2 deletion in PyMT tumors. Deletion of Lats1 is phenotypically distinct from Lats2 deletion in PyMT.

Deletion of Lats1 is phenotypically distinct from Lats2 deletion in PyMT tumors. Deletion of Lats1 is phenotypically distinct from Lats2 deletion in PyMT.
LATS2 promotes death of lumB cells.

LATS2 promotes death of lumB cells.
A, left: indicated MEFs were transfected as described in the Methods section. A, left: indicated MEFs were transfected as described in the Methods section.

A, left: indicated MEFs were transfected as described in the Methods section. A, left: indicated MEFs were transfected as described in the Methods section.

Similar presentations

Ads by Google