AJKD Atlas of Renal Pathology: Diabetic Nephropathy Behzad Najafian, MD, Agnes B. Fogo, MD, Mark A. Lusco, MD, Charles E. Alpers, MD  American Journal of Kidney Diseases  Volume 66, Issue 5, Pages e37-e38 (November 2015) DOI: 10.1053/j.ajkd.2015.08.010 Copyright © 2015 National Kidney Foundation, Inc. Terms and Conditions

Figure 1 (A) Diabetic nephropathy with diffuse mesangial expansion and arteriolar hyalinosis (red arrow). (B) Diabetic nephropathy with nodular mesangial expansion (Kimmelstiel-Wilson nodules) and concomitant hyalinosis of afferent and efferent arterioles (red arrows; Jones silver stain). American Journal of Kidney Diseases 2015 66, e37-e38DOI: (10.1053/j.ajkd.2015.08.010) Copyright © 2015 National Kidney Foundation, Inc. Terms and Conditions

Figure 2 Advanced diabetic nephropathy with Kimmelstiel-Wilson nodule (upper asterisk) with adjacent mesangiolysis (yellow arrow) and a microaneurysm (white arrow) with prominent arteriolar hyalinosis (red arrow). There is a capsular drop (lower asterisk) on Bowman capsule (Jones silver stain). American Journal of Kidney Diseases 2015 66, e37-e38DOI: (10.1053/j.ajkd.2015.08.010) Copyright © 2015 National Kidney Foundation, Inc. Terms and Conditions

Figure 3 Advanced diabetic nephropathy with prominent thickening of glomerular basement membranes with expanded mesangium, predominantly due to increased mesangial matrix. There is segmental foot process effacement, indicative of podocyte injury (electron microscopy). American Journal of Kidney Diseases 2015 66, e37-e38DOI: (10.1053/j.ajkd.2015.08.010) Copyright © 2015 National Kidney Foundation, Inc. Terms and Conditions

Figure 4 Diabetic nephropathy with tubular basement membrane thickening in nonatrophic tubules (electron microscopy). American Journal of Kidney Diseases 2015 66, e37-e38DOI: (10.1053/j.ajkd.2015.08.010) Copyright © 2015 National Kidney Foundation, Inc. Terms and Conditions