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AJKD Atlas of Renal Pathology: Light Chain Proximal Tubulopathy

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Presentation on theme: "AJKD Atlas of Renal Pathology: Light Chain Proximal Tubulopathy"— Presentation transcript:

1 AJKD Atlas of Renal Pathology: Light Chain Proximal Tubulopathy
Agnes B. Fogo, MD, Mark A. Lusco, MD, Behzad Najafian, MD, Charles E. Alpers, MD  American Journal of Kidney Diseases  Volume 67, Issue 2, Pages e9-e10 (February 2016) DOI: /j.ajkd Copyright © 2016 National Kidney Foundation, Inc. Terms and Conditions

2 Figure 1 Light chain proximal tubulopathy with intracytoplasmic crystalline material within proximal tubule epithelium (hematoxylin and eosin stain). American Journal of Kidney Diseases  , e9-e10DOI: ( /j.ajkd ) Copyright © 2016 National Kidney Foundation, Inc. Terms and Conditions

3 Figure 2 (A) Light chain proximal tubulopathy with monoclonal staining for κ light chain within proximal tubule epithelium. (B) There is no staining for λ light chain (immunofluorescence microscopy; same fields stained for κ and λ light chains). American Journal of Kidney Diseases  , e9-e10DOI: ( /j.ajkd ) Copyright © 2016 National Kidney Foundation, Inc. Terms and Conditions

4 Figure 3 Light chain proximal tubulopathy with crystalline structures within the cytoplasm of proximal tubular epithelium (electron microscopy). American Journal of Kidney Diseases  , e9-e10DOI: ( /j.ajkd ) Copyright © 2016 National Kidney Foundation, Inc. Terms and Conditions


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