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Behzad Najafian, MD, Mark A. Lusco, MD, Laura S. Finn, MD, Charles E

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Presentation on theme: "Behzad Najafian, MD, Mark A. Lusco, MD, Laura S. Finn, MD, Charles E"— Presentation transcript:

1 AJKD Atlas of Renal Pathology: Lecithin–Cholesterol Acyltransferase (LCAT) Deficiency 
Behzad Najafian, MD, Mark A. Lusco, MD, Laura S. Finn, MD, Charles E. Alpers, MD, Agnes B. Fogo, MD  American Journal of Kidney Diseases  Volume 70, Issue 1, Pages e5-e6 (July 2017) DOI: /j.ajkd Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

2 Figure 1 Lecithin–cholesterol acyltransferase deficiency with mild mesangial expansion with slight foamy appearance. Capillary walls show segmental thickening (hematoxylin and eosin stain). American Journal of Kidney Diseases  , e5-e6DOI: ( /j.ajkd ) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

3 Figure 2 Lecithin–cholesterol acyltransferase deficiency with segmental thickening and duplication of capillary loops with mild mesangial expansion. Spiculation of glomerular basement membranes mimics membranous nephropathy (arrow). This glomerulus has segmental sclerosis (left) secondary to LCAT deficiency (Jones silver stain). American Journal of Kidney Diseases  , e5-e6DOI: ( /j.ajkd ) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

4 Figure 3 Lecithin–cholesterol acyltransferase deficiency with subepithelial, intramembranous, subendothelial and mesangial lipid deposits (electron microscopy). American Journal of Kidney Diseases  , e5-e6DOI: ( /j.ajkd ) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions


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