Association Between Consumption of Red and Processed Meat and Pancreatic Cancer Risk: A Systematic Review and Meta-analysis  Zhanwei Zhao, Zifang Yin,

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Presentation transcript:

Association Between Consumption of Red and Processed Meat and Pancreatic Cancer Risk: A Systematic Review and Meta-analysis  Zhanwei Zhao, Zifang Yin, Zhongshu Pu, Qingchuan Zhao  Clinical Gastroenterology and Hepatology  Volume 15, Issue 4, Pages 486-493.e10 (April 2017) DOI: 10.1016/j.cgh.2016.09.143 Copyright © 2017 AGA Institute Terms and Conditions

Figure 1 Flowchart of process for identification of relevant studies. Clinical Gastroenterology and Hepatology 2017 15, 486-493.e10DOI: (10.1016/j.cgh.2016.09.143) Copyright © 2017 AGA Institute Terms and Conditions

Figure 2 Forest plots of cohort studies for red meat consumption (highest vs lowest category) and PC risk (random-effects model). (A) Red meat consumption and PC risk. (B) Red meat consumption and PC risk in men. (C) Red meat consumption and PC risk in women. Negative relationship was found between red meat consumption and PC risk (P = .09). Positive relationship was found in men (P < .01) but not in women (P = .61). SE, standard error. Clinical Gastroenterology and Hepatology 2017 15, 486-493.e10DOI: (10.1016/j.cgh.2016.09.143) Copyright © 2017 AGA Institute Terms and Conditions

Figure 3 Forest plots of cohort studies for processed meat consumption (highest vs lowest category) and PC risk (random-effects model). (A) Processed meat consumption and PC risk. (B) Processed meat consumption and PC risk in men. (C) Processed meat consumption and PC risk in women. Negative relationship was found between red meat consumption and PC risk (P = .18). Positive relationship was found in men (P < .01) but not in women (P = .88). SE, standard error. Clinical Gastroenterology and Hepatology 2017 15, 486-493.e10DOI: (10.1016/j.cgh.2016.09.143) Copyright © 2017 AGA Institute Terms and Conditions

Supplementary Figure 1 Forest plots of case-control studies for red and processed meat consumption (highest vs lowest category) and PC risk (random-effects model). (A) Red meat; (B) processed meat. SE, standard error. Clinical Gastroenterology and Hepatology 2017 15, 486-493.e10DOI: (10.1016/j.cgh.2016.09.143) Copyright © 2017 AGA Institute Terms and Conditions

Supplementary Figure 2 Nonlinear associations between (A) red meat consumption and (B) processed meat consumption and PC risk. Clinical Gastroenterology and Hepatology 2017 15, 486-493.e10DOI: (10.1016/j.cgh.2016.09.143) Copyright © 2017 AGA Institute Terms and Conditions

Supplementary Figure 3 Funnel plots of cohort studies evaluating publication bias of (A) red meat and (B) processed meat consumption and PC risk. SE, standard error. Clinical Gastroenterology and Hepatology 2017 15, 486-493.e10DOI: (10.1016/j.cgh.2016.09.143) Copyright © 2017 AGA Institute Terms and Conditions