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Mucosal Healing Is Associated With Improved Long-term Outcomes of Patients With Ulcerative Colitis: A Systematic Review and Meta-analysis  Shailja C.

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Presentation on theme: "Mucosal Healing Is Associated With Improved Long-term Outcomes of Patients With Ulcerative Colitis: A Systematic Review and Meta-analysis  Shailja C."— Presentation transcript:

1 Mucosal Healing Is Associated With Improved Long-term Outcomes of Patients With Ulcerative Colitis: A Systematic Review and Meta-analysis  Shailja C. Shah, Jean-Frederic Colombel, Bruce E. Sands, Neeraj Narula  Clinical Gastroenterology and Hepatology  Volume 14, Issue 9, Pages e8 (September 2016) DOI: /j.cgh Copyright © 2016 AGA Institute Terms and Conditions

2 Figure 1 Flow diagram of study search.
Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2016 AGA Institute Terms and Conditions

3 Figure 2 Association of MH1 and long-term CR. M-H, mucosal healing.
Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2016 AGA Institute Terms and Conditions

4 Figure 3 Association of MH1 and colectomy-free rate at follow-up. M-H, mucosal healing. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2016 AGA Institute Terms and Conditions

5 Figure 4 Association of MH1 and long-term MH. M-H, mucosal healing.
Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2016 AGA Institute Terms and Conditions

6 Supplementary Figure 1 Association of MH1 and long-term CS-free CR. M-H, mucosal healing. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2016 AGA Institute Terms and Conditions

7 Supplementary Figure 2 Funnel plot assessing publication bias of long-term CR. OR, odds ratio; SE, standard error. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2016 AGA Institute Terms and Conditions

8 Supplementary Figure 3 Association of MH1 and long-term CR: biologic therapy vs non-biologic therapy. M-H, mucosal healing. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2016 AGA Institute Terms and Conditions

9 Supplementary Figure 4 Association of MH1 and colectomy-free rate at follow-up: biologic therapy vs non-biologic therapy. M-H, mucosal healing. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2016 AGA Institute Terms and Conditions

10 Supplementary Figure 5 Association of MH1 and long-term MH: biologic therapy vs non-biologic therapy. M-H, mucosal healing. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2016 AGA Institute Terms and Conditions

11 Supplementary Figure 6 Association of MH1 and long-term CR: RCTs vs non-RCTs. M-H, mucosal healing. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2016 AGA Institute Terms and Conditions

12 Supplementary Figure 7 Association of MH1 and colectomy-free rate at follow-up: RCTs vs non-RCTs. M-H, mucosal healing. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2016 AGA Institute Terms and Conditions

13 Supplementary Figure 8 Association of MH1 and CR at follow-up <2 y vs ≥2 y. M-H, mucosal healing. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2016 AGA Institute Terms and Conditions

14 Supplementary Figure 9 Association of MH1 and colectomy-free rate at follow-up <2 y vs ≥2 y. M-H, mucosal healing. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2016 AGA Institute Terms and Conditions

15 Supplementary Figure 10 Association of MH1 and MH at follow-up <2 y vs ≥2 y. M-H, mucosal healing. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2016 AGA Institute Terms and Conditions


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