An Introduction to the NIHR programmes Professor Tom Walley 9 February 2012

Decline in clinical research in surgery Service demands Lack of equipoise Lack of expertise in clinical trials Easier ways to keep RAE/university happy (consent, regulation of clinical trials etc) But: Lack of information to inform practice Professional (eg RCS, ASGBI) enthusiasm for more clinical research

Call for Applied Research in Surgery Application forms available on 23 February. Closing date 25 May 2012 Particular interests Surgical procedures Alternatives to surgery (surgical comparators) Patient safety/experiences Devices Organisation of services

What is applied research? Research with the capacity to improve patient outcomes and NHS services Clinical research (not only trials) Not Discovery science Animal See remit of participating programmes - if in doubt ask

Participating programmes CCF programmes Invention for Innovation Programme (i4i) Programme Grants for Applied Research Programme Programme Development Grants Research for Patient Benefit Programme NETS programmes HTA EME HS&DR

The NIHR Health Research System Faculty Investigators & Senior Investigators Associates Trainees Universities Infrastructure Research Clinical Research Networks NHS Trusts Research Projects & Programmes Patients & Public Clinical Research Facilities, Centres & Units Research Schools Make reference to CCF as the other funder of NIHR research programmes Research Governance Systems Research Information Systems Systems

National Institute for Health Research INVENTION EVALUATION ADOPTION DIFFUSION Basic Research Development Pathway Funding MRC Efficacy & Mechanism Evaluation Invention for Innovation Biomedical Research Centres This pathway covers the full range of interventions - pharmaceuticals, biologicals, biotechnologies, procedures, therapies and practices - for the full range of health and health care delivery - prevention, detection, diagnosis, prognosis, treatment, care. Biomedical Research Units Patient Safety and Quality Research Centres Research for Innovation, Speculation & Creativity Research for Patient Benefit Health Services & Delivery Research National Institute for Health Research Programme Grants for Applied Research Public Health Research Health Technology Assessment Collabs for Ldrshp in Appl Hlth Res and Care Ctr for Reviews & Dissemination, Cochrane, TARs NHS Purchasing & Supplies Agency Centre for Evidence-based Purchasing National Institute for Health & Clinical Excellence Guidance on Health & Healthcare NHS Evidence Access to Evidence NHS Institute for Innovation & Improvement Support for the NHS Strategic Health Authorities Duty of Innovation Primary Care Trusts Healthcare Commissioning NHS Providers Patient Care

Clinical Research Networks NIHR as a system Clinical Research Networks Joint calls Facilitating researchers, speeding review Transfers between NIHR programmes Active collaboration between programmes Directors' meetings Meeting with networks CCF i4i PGfAR RfPB NETSCC HS&DR HTA EME

Which programme? Visit the market place EME – exploratory trials, less pragmatic, phase 2-3, efficacy, mechanisms if possible? HTA – systematic reviews, large multicentre pragmatic trials or other studies (phase 3-4), effectiveness in the NHS HS&DR – organisational, patient experience, qualitative or other i4i - translation of bright ideas for new high-tech products into methods of prevention, diagnosis and treatment PGfAR- £2m for up to 5 years, awards made to NHS bodies RfPB – max £250k for up to three years

Themed Call on Research in Surgery Watch the website for dates Engage collaborators, CTUs, RDS as soon as you can Closing date for outlines (vary by programme, not RfPB) May 25th Closing dates for fulls (vary by programme) October Final funding decisions March 2013

Thank you 9 February 2012