Fig. 6. N95BA5 biocompatibility beyond intended use frame.

Slides:

Advertisements

Similar presentations

In vitro tissue engineering of a cardiac graft using a degradable scaffold with an extracellular matrix–like topography Osamu Ishii, MD, Michael Shin,

Advertisements

Fig. 1. TP is highly expressed in myeloma.

Kenichi Fujii et al. JIMG 2015;8:

Fig. 2. LUM015 fluorescently labels tumor cells in mouse models of STS and breast cancer. LUM015 fluorescently labels tumor cells in mouse models of STS.

Fig. 3. Ultrasound-mediated BMP-6 gene delivery to mini-pig tibial bone fractures. Ultrasound-mediated BMP-6 gene delivery to mini-pig tibial bone fractures.

Fig. 6. AZD6738 induces DNA damage and apoptosis and exhibits antitumor efficacy in xenograft models of high-risk medulloblastoma and neuroblastoma. AZD6738.

Fig. 3. Features of PH in KRasLA2 transgenic mice.

Fig. 4. Intramuscular injection of AAV9-Cas9/sgRNA-51 corrects dystrophin expression. Intramuscular injection of AAV9-Cas9/sgRNA-51 corrects dystrophin.

Fig. 6. Ex vivo and in vivo test to evaluate the sealing capability of the MeTro sealant using a porcine lung incision model. Ex vivo and in vivo test.

Fig. 4. Liver HBV mRNA paired-end sequencing reads in HBeAg-positive and HBeAg-negative chimpanzees. Liver HBV mRNA paired-end sequencing reads in HBeAg-positive.

Fig. 4. Hydrogel particle size and gelation mechanism.

Fig. 1 Localized treatment of TNBC cancers kills tumor cells and minimizes the metastatic burden. Localized treatment of TNBC cancers kills tumor cells.

Fig. 4. Prion infectivity of skin samples from sCJD patients.

Fig. 3. Serum HBsAg and liver HBV mRNA reduction in chimpanzees dosed with ARC-520. Serum HBsAg and liver HBV mRNA reduction in chimpanzees dosed with.

Fig. 1. NASH and fibrosis develop late in mice fed an HFD.

Fig. 8. mRIPO elicits neutrophil influx followed by DC and T cell infiltration into tumors. mRIPO elicits neutrophil influx followed by DC and T cell infiltration.

Fig. 4 Topical application of SAAP-148 ointment eradicates acute and established infections of MRSA and A. baumannii from the skin. Topical application.

Fig. 4. Characterization of human liver seed graft morphology.

Fig. 4 Bone tissue formation within the Ti-mesh channels.

Fig. 5. Immunohistochemistry of the tumor microenvironment in GBM specimens before and after CART-EGFRvIII infusion. Immunohistochemistry of the tumor.

Expression of CD36 and psap in a TMA of human ovarian cancer patients

Fig. 4 Expression of cleaved caspase 3, PD-L1, and PD-1 in HGGs after reovirus treatment. Expression of cleaved caspase 3, PD-L1, and PD-1 in HGGs after.

Histology samples stained with Masson trichrome.

Fig. 5. Preliminary performance validation of the hydrogel in vivo in a rabbit model of scleral trauma. Preliminary performance validation of the hydrogel.

Fig. 5. Vascularization of human liver seed grafts.

Enhanced Cutaneous Inflammatory Reactions to Aspergillus fumigatus in a Murine Model of Chronic Granulomatous Disease Jeffrey E. Petersen Journal of.

Fig. 5 Acute loss of mitochondrial content after impact is prevented by inhibition of electron transport or critical redox events. Acute loss of mitochondrial.

Fig. 1. Generation of the ΔEx50 mouse model.

Fig. 2 In vitro assessment of hESC-RPE cell sheets.

Fig. 2 STED microscopy of isolated cardiomyocytes from mice treated with MP-rhodamine–loaded CaPs. STED microscopy of isolated cardiomyocytes from mice.

Fig. 2. Rheological characterization and hydrogel differentiation.

Fig. 5. MasSpec Pen analysis of an HGSC tissue sample with mixed histologic composition. MasSpec Pen analysis of an HGSC tissue sample with mixed histologic.

NFATc2-deficient mice do not eliminate skin C. albicans infections.

Fig. 3 hESC-RPE cell sheet transplantation and validation of the surgical method. hESC-RPE cell sheet transplantation and validation of the surgical method.

Fig. 5 EGFR mutation status of patients with NSCLC, detected by histological examination and ARMS PCR. EGFR mutation status of patients with NSCLC, detected.

Role of immune and inflammatory cells in lung cancer–associated PH

Fig. 4. Irisin protected against oxidative stress and apoptosis in IR-injured lung tissue. Irisin protected against oxidative stress and apoptosis in IR-injured.

The pathophysiological processes linked to kidney disease.

Fig. 3 Histomorphological evaluation of the segmental defect healing.

Fig. 7 CSPG4-high GBMs show more microglia than CSPG4-low GBMs and express TNFα. CSPG4-high GBMs show more microglia than CSPG4-low GBMs and express TNFα.

Fig. 6. pKL cells revert hyperglycemia in NOD mice in vivo.

Fig. 7. Genetic ablation of UCP2 compromised the protective effect of exogenous irisin on lung IR injury. Genetic ablation of UCP2 compromised the protective.

Fig. 2 Analysis of CLL lymph nodes.

PAAND is driven by local inflammasome activation and IL-1β production

Fig. 4. Features of PH in LLC1 lung tumor mice.

Fig. 4. The effect of single-dose rozanolixizumab on the concentration of IgG subtypes in healthy subjects. The effect of single-dose rozanolixizumab on.

Fig. 4. Acute lung injury in miR-223−/y mice.

Fig. 3 CSF1 is expressed in human melanoma.

Fig. 8 Analysis of bone structure within the soft and stiff scaffold.

Fig. 7 Analysis of the bacterial nidus within tissue abscesses by MALDI IMS demonstrates a paucity of calprotectin signal. Analysis of the bacterial nidus.

Fig. 7 Vaccine-induced influenza-specific B cells are not maintained in peripheral blood. Vaccine-induced influenza-specific B cells are not maintained.

Fig. 6 Photoreceptor cell survival in the RCS rat retina after transplantation with hESC-RPE cell sheets. Photoreceptor cell survival in the RCS rat retina.

IIV induces CD21hiCD27+ and CD21loCD27+ influenza-specific B cells

Fig. 1 LB100 and LB102 specifically inhibit PP2A phosphatase activity and the growth of BCR-ABL+ cells. LB100 and LB102 specifically inhibit PP2A phosphatase.

Correlation of reovirus RNA/protein with proliferating tumor cells

Fig. 1 Neutrophils derived from patients with MPNs are associated with an increase in NET formation and a prothrombotic, NET-rich phenotype. Neutrophils.

Fig. 6 Combination therapy with LVSOD2 and LVshCTGF preserves flap volume and reduces fibrosis after RT. Combination therapy with LVSOD2 and LVshCTGF preserves.

Effect of PV1(RIPO) on s.c.

Fig. 7 Transient immunosuppression (4 weeks) supports long-term graft survival and is associated with progressive decrease in spinal regional inflammatory.

Fig. 6 Knockdown of nestin impaired tendon repair and regeneration in a rat model of patellar tendon defect. Knockdown of nestin impaired tendon repair.

Biocompatibility evaluation in vivo with a mouse subcutaneous implant

Fig. 6. Nontaxane chemotherapies induce TMEM-dependent prometastatic changes in the breast cancer microenvironment. Nontaxane chemotherapies induce TMEM-dependent.

Genetic EGFR ablation in K-RAS–mutated lung AC reduces tumor growth

Adult Acvr1;Trp53DCKO lenses form vascularized, tumor-like structures at their posterior poles. 4-month-old Trp53CKO and Acvr1;Trp53DCKO lenses were sectioned.

Serial biopsy samples taken from the patient in figs 1and 2, showing from left to right: acute myocarditis, healing myocarditis, dilated cardiomyopathy.

Fig. 1. Matrix stiffness sensitizes myofibroblasts to apoptosis induced by inhibition of their mechanotransduction pathways. Matrix stiffness sensitizes.

Fig. 6. Confocal image series at 10-μm intervals through the full retinal thickness at P48 in WT and vldlr-null mice. Confocal image series at 10-μm intervals.

Fig. 6 Antitumor effect on tumor growth and pulmonary metastasis of CSSD-9 in vivo. Antitumor effect on tumor growth and pulmonary metastasis of CSSD-9.

a b c Supplementary Figure 1

Figure 4. Histological features of defect healing 7 weeks after defect creation (Masson trichrome staining, scale bar=1 mm). Group 1 (A) showed notable.

Presentation transcript:

Fig. 6. N95BA5 biocompatibility beyond intended use frame. N95BA5 biocompatibility beyond intended use frame. (A) Series of histological cross sections prepared for control (left pairs) and treatment (right pairs) in hematoxylin and eosin (H&E) and Masson’s trichrome stain for each of the study endpoints (t = 48 hours, 1 week, and 4 week). Scale bars, 800 μm. (B) Increased magnification of one of the laceration margins for the treatment group showing evolution of the tissue-hydrogel interface from acute inflammatory infiltrate to a mature, compact fibrotic encapsulation layer at 4 weeks. Scale bars, 50 μm. (C) Gross visualization (top row) and high-magnification (bottom row) evaluation of treatment group retinas showing no evidence of trauma-induced retinal detachment or hydrogel-induced retinal neurotoxicity. Scale bars, 5 mm (top row) and 100 μm (bottom row). Niki Bayat et al., Sci Transl Med 2017;9:eaan3879 Published by AAAS