Introduction and Background NeSSI* & Micro-Analytics Workshop (* New Sampling/Sensor Initiative) Introduction and Background “the best way to predict the future is to create it” 2003 Spring Sponsor Meeting Center for Process Analytical Chemistry

Our Process Analytics Legacy Same Sampling System Design Practice for 20+ years Discrete components & Basically Dumb Lack of standardization Result: Recognized as Weakest Link in Analyzer System Typically Battleship Designs for Analyzers Not real-estate friendly Ambient and environmentally challenged (read “ require A/C shelters”) Poor Connectivity Requires brute force methods for analyzer system integration (including critical interface to the process Control System)

 Hierarchical/Domain Connectivity Model for Process Analyzer System Level 3 LAN Enterprise Domain Level 4 Enterprise LAN L4 Safety Control/ Optimization Environmental L3 DCS Domain O&M Domain c-LAN AnLAN L2 Primary Data Path > Requires Maximum Integrity/Reliability Level 2 LAN = Field LAN Secondary Data Path > Requires High Integrity/Reliability Measurement Domain  SAM eSAM Level 1 Sensor Bus (CAN) L1 L0

Our Process Analytics Legacy Same Sampling System Design Practice for 20+ years NeSSI Gen I/II Level 2 LAN = Field LAN Measurement Domain  SAM eSAM Level 1 Sensor Bus (CAN)

Our Process Analytics Legacy Typically Battleship Designs for Analyzers NeSSI Gen II/III Micro-analytics, “by-line” Level 2 LAN = Field LAN Measurement Domain  SAM eSAM Level 1 Sensor Bus (CAN)

Our Process Analytics Legacy Poor Connectivity ConnI Ethernet TCP/IP CAN-bus, DeviceNet Level 2 LAN = Field LAN Measurement Domain  SAM eSAM Level 1 Sensor Bus (CAN)

Legacy Left us with the following Impressions ...... complex expensive proprietary “big box” outdoor operation hi maintenance industry: slow to change Edvard Munch “The Scream” And hurting us in the following areas ...... Cost to Build Cost to Own/Operate Reliability

The Drivers for Process Analytical Change Reduce Cost to Build Design and Engineering Manufacturing and Installation Reduce Cost of Ownership Design Standardization Simpler, less expensive maintenance Enhance Reliability (Measurement Data Fit for Purpose) Validate sample, data, communication

NeSSI Initiative An ad hoc global industry initiative, formed in June, 2000 to drive permanent change in Sampling and Sensor Design and Implementation Composed of End Users, Manufacturing Companies, Integrators NeSSI mail-out has now grown to 350+ subscribers Sponsored by the Center for Process Analytical Chemistry (CPAC) - legal umbrella End User driven

NeSSI Objectives Facilitate the acceptance/implementation of modular, miniature & smart sampling system and sensor platform (Adopt/adapt surface mount technology from SEMI) Promote the concept of at the pipe/field-mounted (“byline”) analytical systems Lay the groundwork for an open connectivity communication architecture down to lowest level of sampling system sensors/actuators (integrate NeSSI with ConnI) Promote NeSSI as the macro-to-micro sampling platform for the emerging generation of micro-analyzers (e.g. “sensor/lab-on-a-chip” microanalytical devices)

NeSSI Vision - Gen I (Available Now) Courtesy of a gulf coast petrochemical facility

NeSSI an Enabling Technology/Platform What you will learn today: NeSSI has evolved as a Sampling & Connectivity Platform Sampling Interface based on an ANSI/ISA 76 Standard Connectivity Interface Standard Sensor bus (DeviceNet) Standard Ethernet Interface for system integration Primary Benefit: Platform enables accelerated development /commercialization of the new generation mini/micro analytical sensors/system (emphasis can be on analytical sensor) 3 Generations of NeSSI envisioned to fully exploit NeSSI capabilities Analytical Application Clusters (enabler for sensor arrays)

NeSSI History Concept of Modular Sampling System based on SEMI design conceived at ISA AD Meeting in 1998 Groundwork for NeSSI started at Nov 99 CPAC meeting Initiative initiated in June 2000 (Issued RFP) NeSSI promoted mainly at ISA and IFPAC meetings Chronology of events trail at NeSSI Website

Workshop Goals: Provide an overview of the technology trends and hurdles in the commercialization of the new generation mini and micro-analytical analyzers and sensors (MAS) Validate and promote NeSSI as a MAS enabling platform with respect to both standardized sampling and connectivity interfaces Explore and propose an enabling organizational mechanism such as an Analytics Interest Group, Forum etc. which would promote and facilitate the development, testing and deployment (commercialization) of the next generation of MAS systems