Pharmacological prevention of sevoflurane- and desflurane-related emergence agitation in children: a meta-analysis of published studies  S Dahmani, I.

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Presentation transcript:

Pharmacological prevention of sevoflurane- and desflurane-related emergence agitation in children: a meta-analysis of published studies  S Dahmani, I Stany, C Brasher, C Lejeune, B Bruneau, C Wood, Y Nivoche, I Constant, I Murat  British Journal of Anaesthesia  Volume 104, Issue 2, Pages 216-223 (February 2010) DOI: 10.1093/bja/aep376 Copyright © 2010 The Author(s) Terms and Conditions

Fig 1 Meta analysis flowchart. RCT, randomized controlled trials. British Journal of Anaesthesia 2010 104, 216-223DOI: (10.1093/bja/aep376) Copyright © 2010 The Author(s) Terms and Conditions

Fig 2 Forest plot of meta-analysis of propofol prevention in EA (propofol n=442, control n=450). The square shown for each study (first author and year of publication) is the OR for individual trials, and the corresponding horizontal line is the 95% confidence interval (CI). The diamond is the pooled OR with the 95% CI. Studies with more than one intervention group were numbered (author, year of publication_1) and (author, year of publication _2). British Journal of Anaesthesia 2010 104, 216-223DOI: (10.1093/bja/aep376) Copyright © 2010 The Author(s) Terms and Conditions

Fig 3 Forest plot of meta-analysis of α2-AR agonists prevention in EA (α2-AR n=418, control n=339). The square shown for each study (first author and year of publication) is the OR for individual trials, and the corresponding horizontal line is the 95% CI. The diamond is the pooled OR with the CI. Studies with more than one intervention group were numbered (author, year of publication_1) and (author, year of publication _2). British Journal of Anaesthesia 2010 104, 216-223DOI: (10.1093/bja/aep376) Copyright © 2010 The Author(s) Terms and Conditions

Fig 4 Forest plot of meta-analysis of fentanyl prevention in EA (fentanyl n=341, control n=215). The square shown for each study (first author and year of publication) is the OR for individual trials, and the corresponding horizontal line is the 95% CI. The diamond is the pooled OR with the 95% CI. Studies with more than one intervention group were numbered (author, year of publication_1) and (author, year of publication _2). British Journal of Anaesthesia 2010 104, 216-223DOI: (10.1093/bja/aep376) Copyright © 2010 The Author(s) Terms and Conditions

Fig 5 Funnel plot of the studies included in propofol meta-analysis. British Journal of Anaesthesia 2010 104, 216-223DOI: (10.1093/bja/aep376) Copyright © 2010 The Author(s) Terms and Conditions

Fig 6 Funnel plot of the studies included in α2-AR agonists meta-analysis. British Journal of Anaesthesia 2010 104, 216-223DOI: (10.1093/bja/aep376) Copyright © 2010 The Author(s) Terms and Conditions

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