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Optimal bolus dose of alfentanil for successful tracheal intubation during sevoflurane induction with and without nitrous oxide in children†  H.J. Kwak,

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Presentation on theme: "Optimal bolus dose of alfentanil for successful tracheal intubation during sevoflurane induction with and without nitrous oxide in children†  H.J. Kwak,"— Presentation transcript:

1 Optimal bolus dose of alfentanil for successful tracheal intubation during sevoflurane induction with and without nitrous oxide in children†  H.J. Kwak, J.Y. Kim, S.K. Min, J.S. Kim, J.Y. Kim  British Journal of Anaesthesia  Volume 104, Issue 5, Pages (May 2010) DOI: /bja/aeq055 Copyright © 2010 The Author(s) Terms and Conditions

2 Fig 1 The CONSORT flowchart.
British Journal of Anaesthesia  , DOI: ( /bja/aeq055) Copyright © 2010 The Author(s) Terms and Conditions

3 Fig 2 Sequences of the dose of alfentanil for successful intubation in the O2 group (a) and the N2O group (b) using the technique of up-and-down sequential allocation. The horizontal lines represent the mean and 95% CI. The ED50 of alfentanil in the O2 and N2O groups (95% CI) was 11.5 (9.9–13.1) and 8.6 (7.4–9.8) µg kg−1, respectively. British Journal of Anaesthesia  , DOI: ( /bja/aeq055) Copyright © 2010 The Author(s) Terms and Conditions

4 Fig 3 PAVA response rate in the O2 and N2O groups. The 50% effective dose (ED50) (95% CI) of alfentanil in the O2 and N2O groups was 11.4 (9.9–13.0) and 6.5 (5.0–8.1) µg kg−1, respectively. The ED95 (95% CI) of alfentanil estimated from the PAVA response rate in the O2 and N2O groups was 14.0 (12.1–15.9) and 10.7 (9.5–11.9) µg kg−1, respectively. British Journal of Anaesthesia  , DOI: ( /bja/aeq055) Copyright © 2010 The Author(s) Terms and Conditions


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