1. Duration of Dual Antiplatelet Therapy in Patients with an Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention 
Chirag Bavishi, MD, MPH, Vrinda Trivedi, MD, Mandeep Singh, MD, Edward Katz, MD, Franz H. Messerli, MD, Sripal Bangalore, MD, MHA 
The American Journal of Medicine 
Volume 130, Issue 11, Pages 1325.e e12 (November 2017)
DOI: /j.amjmed
Copyright © 2017 Elsevier Inc. Terms and Conditions

2. Figure 1
Flowchart of study selection. ACS = acute coronary syndrome; RCT = randomized controlled trial.
The American Journal of Medicine  , 1325.e e12DOI: ( /j.amjmed )
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3. Figure 2
Forest plot of (A) cardiovascular mortality and (B) myocardial infarction with trial-defined shorter- vs longer-duration Dual antiplatelet therapy (DAPT) in patients with an acute coronary syndrome. Data stratified by duration of DAPT: short-term (≤6 months) vs 12-month or extended DAPT; and 12-month vs extended (>12 months) DAPT. Squares represent the risk ratio of the individual studies; horizontal lines represent the 95% confidence intervals (CI) of the risk ratio. The size of the squares reflects the weight that the corresponding study contributes in the meta-analysis. The diamonds represents the pooled risk ratio or the overall effect. CI = confidence interval.
The American Journal of Medicine  , 1325.e e12DOI: ( /j.amjmed )
Copyright © 2017 Elsevier Inc. Terms and Conditions

4. Figure 3
Forest plot of (A) stent thrombosis and (B) major bleeding with trial-defined shorter vs longer duration DAPT in patients with an acute coronary syndrome. Data stratified by duration of DAPT: short-term (≤6 months) vs 12-month or extended DAPT; and 12-month vs extended (>12 months) DAPT. Other notations as in Figure 2.
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5. Supplementary Figure 1
Forest plot of all-cause mortality with trial-defined shorter vs longer duration dual antiplatelet therapy (DAPT) in patients with acute coronary syndrome (ACS). CI = confidence interval.
The American Journal of Medicine  , 1325.e e12DOI: ( /j.amjmed )
Copyright © 2017 Elsevier Inc. Terms and Conditions

6. Supplementary Figure 2
Funnel plot of publication bias for all outcomes. RR = relative risk.
The American Journal of Medicine  , 1325.e e12DOI: ( /j.amjmed )
Copyright © 2017 Elsevier Inc. Terms and Conditions