What does this protein make up or do? SA A Chapter 1: Chromosome 1 DNA Sequence Chromosome 81,519 bp Name of Protein 1 Name of Gene Ski uncogene SKI transcription Amino acid sequence mRNA 728 aa translation Cytoplasm A Cell Nucleus What does this protein make up or do? SA A The SKI gene provides instructions for making a protein involved in a signaling pathway that transmits chemical signals from the cell surface to the nucleus. Condition/Disease Breast Cancer

Description of Glaucoma Symptoms and characteristics A change in how the breast or nipple feels A change in the breast or nipples appearance Any nipple discharge- particularly clear discharge or bloody discharge. Breast cancer is a malignant tumor that starts in the cells of the breast. A malignant tumor is a group of cancer cells that can grow into (invade) surrounding tissues or spread (metastasize) to distant areas of the body. The disease occurs almost entirely in women, but men can get it, too. https://www.google.com/search?q=before+and+after+breast+cancer&espv=2&biw=1024&bih=677&source=lnms&tbm=isch&sa=X&ei=Y3H3VMuNNIXaoAT_1oKoAQ&ved=0CAYQ_AUoAQ#tbm=isch&tbs=rimg%3ACTkjgtQsJn_1jIjhmwhnTrb60H0PcWfscVP3aHAwUO3t-4-qHc_1HrJsU1ZyB_18_1dla2j3JIATl5qXQqjtJXA_1FKOEbyoSCWbCGdOtvrQfETxY0Jeju8TSKhIJQ9xZ-xxU_1doRl9SjuypIvKkqEgkcDBQ7e37j6hGI1edtEgH5wCoSCYdz8esmxTVnEd8L8RJGgIQ0KhIJIH_1z92VraPcRQRhFW_1tzSLkqEgkkgBOXmpdCqBGzjbQp1r8ShyoSCe0lcD8Uo4RvEYx9i1tuJkou&q=before%20and%20after%20breast%20cancer&imgdii=OSOC1Cwmf-PpMM%3A%3BJIATl5qXQqjuKM%3BOSOC1Cwmf-PpMM%3A&imgrc=OSOC1Cwmf-PpMM%253A%3BQh8eTcEhWR7FbM%3Bhttp%253A%252F%252Fwww.mindfully.org%252FHealth%252FBreast-Cancer-ABCs5_10.jpg%3Bhttp%253A%252F%252Fwww.mindfully.org%252FHealth%252FBreast-Cancer-ABCs.htm%3B600%3B394

Description of Breast Cancer Who is affected? Anyone, but the following have a higher risk: Being female (Breast cancer can occur in men, but it is rare.) Having a family history of breast cancer Having your first child after age 35 or never having children Reaching menopause after age 55 Getting your period early in life (before age 12) Outlook or quality of life Absence of symptoms (such as pain and fatigue) Survival rates are higher in the early stages of breast cancer, early diagnosis and treatment is crucial The hormone receptors on cells with cancer or the types of tissue that the cancer has affected There are some cure to a few types of breast cancer Researcher: DV

References Heathline: Metastic Breast Cancer: Life expectancy and prognosis. Available at: http://www.healthline.com/health/breast-cancer/metastatic-prognosis#Overview1 NCBI: SKI cogene. Available at: http://www.ncbi.nlm.nih.gov/gene/6497 Genetics Home Reference: Chromosome 1. Available at: http://ghr.nlm.nih.gov/chromosome/1#resources Genes on Chromosome 1. Available at: http://ghr.nlm.nih.gov/chromosome/1/show/Genes SKI. Available at: http://ghr.nlm.nih.gov/gene/SKI American Cancer Society: Breast Cancer. Available at: http://www.cancer.org/cancer/breastcancer/detailedguide/breast-cancer-what-is-breast-cancer