1. Chapter 15: Chromosome 15 A Cell Nucleus 71,913 bp 2473 aa 15 aggrecan
DNA Sequence
Chromosome 15
71,913 bp
Name of Protein
aggrecan
Name of Gene
ACAN
transcription
Amino acid sequence
mRNA
2473 aa
translation
Cytoplasm
A Cell
Nucleus
What does this protein make up or do?
gives cartilage its gel-like structure
Condition/Disease
familial osteochondritis dissecans

2. Description of Glaucoma
Symptoms and characteristics
Familial osteochondritis dissecans is a condition that affects the joints and is associated with abnormal cartilage.
Cartilage is a tough but flexible tissue that covers the ends of the bones at joints and is also part of the developing skeleton

3. Description of Glaucoma (cont.)
Who is affected?
Familial osteochondritis dissecans is a rare condition, although the prevalence is unknown. Sporadic osteochondritis dissecans is more common; it is estimated to occur in the knee in 15 to 29 per 100,000 individuals.
Outlook or quality of life
The lesions cause stiffness, pain, and swelling in the joint.
Often, the affected joint feels like it catches or locks during movement.
Treatment usually starts with the least invasive measures first. If these fail, then surgery may be necessary.
Researcher JA

4. References