The overdriven glomerulus as a cardiovascular risk factor

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Presentation transcript:

The overdriven glomerulus as a cardiovascular risk factor Carmine Zoccali, Francesca Mallamaci Kidney International Volume 93, Issue 1, Pages 13-15 (January 2018) DOI: 10.1016/j.kint.2017.08.035 Copyright © 2017 International Society of Nephrology Terms and Conditions

Figure 1 Global and single-nephron glomerular filtration rate (GFR). The sketch on the left (a) depicts the normal situation, and the 10 nephrons in the figure represent the average number of nephrons per kidney (106). The sketches on the right represent a situation of global hyperfiltration where all nephrons hyperfilter (b) and the typical situation that occurs in moderate to severe chronic kidney disease, i.e., a reduced number of functioning nephrons, all hyperfiltering (c). Kidney International 2018 93, 13-15DOI: (10.1016/j.kint.2017.08.035) Copyright © 2017 International Society of Nephrology Terms and Conditions