SWAG SSG Brain Meeting Wednesday 16th November 2016 Clinical Research Network West of England SWAG SSG Brain Meeting Wednesday 16th November 2016

Clinical Research Network & Cancer Services West ofEngland SWAG - Somerset Wiltsire Avon & Gloucestershire South West Children’s Cancer & Leukaemia Research Network

NIHR CRN High Level Objectives Increase number of participants into NIHR CRN portfolio studies 650,000 in England 21,905 in West of England Increase the number of studies that deliver to time and target Target 80% Increase number of commercial studies delivered through network 650 new studies this year 75% of all commercial studies Reduce NHS study set up times Reduce time taken to recruit first participant

Local Clinical Research Networks Translation of national objectives for clinical research Oversight of research activity within the geography of CRN - West of England in terms of: Portfolio Balance, new studies, feasibility, set up, industry trials Performance Support, network wide solutions, targets People Patient involvement, staff skill mix & flexibility, training, resources

30 Clinical Specialties Ageing Anaesthetics & pain Cancer Cardiovascular Children Critical Care Dementia & Neurodegenerative Dermatology Diabetes ENT Gastroenterology Genetics Haematology Health Services Hepatology Infectious Diseases Injuries & Emergencies Mental Health Metabolic & Endocrine Musculoskeletal Neurological Opthalmology Oral & Dental Primary Care Public Health Renal Reproductive Health Respiratory Stroke Surgery

NIHR CRN Objectives for cancer Recruit 20% of cancer incidence West of England 1,909 Recruit 7.5% of cancer incidence into interventional studies 716 Include challenging studies Cancer surgery – 4 recruits per 100,000 population Radiotherapy – 6 recruits per 100,000 population Rare cancers (<6 per 100,000) – 12 recruits per 100,000 population Children & young people – 3 per 100,000 population Teenagers & young adults – record number of 16-25 year olds participating in research

Open studies in SWAG – Brain Cancer 37 BRAG Open studies Black Study not reported recruitment or study has not recruited Red % Recruitment is more than 30 behind % time elapsed, i.e. Difference < -30 Amber % Recruitment is less than 30 behind % elapsed time but more than 0 behind % elapsed time, i.e. -30 < Difference < 0 Green % Recruitment is equal to or greater than % elapsed time, i.e. Difference >= 0 Grey Unable to calculate RAG due to record missing at least one data point

Studies in set up – Brain Cancer

Useful links https://www.crn.nihr.ac.uk/ National and local network information including training programmes templates, tools, contacts, videos etc https://odp.nihr.ac.uk/ http:/ Open data platform. Look at performance across whole CRN including all specialty areas /csg.ncri.org.uk/portfolio/portfolio-maps/ View current national portfolio of open, closed and ‘in set up’ cancer studies https://www.ukctg.nihr.ac.uk/ See where a study is open across the country http://public-odp.nihr.ac.uk/  Search for a study to fit criteria. Good for horizon scanning, eligibility criteria

Contacts Research Delivery Manager – maxine.taylor@nihr.ac.uk Cancer portfolio facilitator – sarah.west@nihr.ac.uk