1. Delivering clinical research to make patients, and the NHS, better Haematological Cancer Research Report Site Specific Group Meeting Tuesday 14 th October 2014 Maxine Taylor Senior Research Delivery Manager

2. Overview of network changes Request for research lead Overview of research activity Discussion re new studies for the portfolio 2

3. CRN - West of England - Population 2.4 million - Budget £13.2 million - 7 Acute Trusts - 2 Mental Health Trusts - CCL Principal Treatment Centre - Full team only since August 1st - Small core support team based at host in Bristol - Not exactly mapping SSGs Bath Bristol Cheltenham Gloucester Weston Super Mare Swindon

4. Purpose Translation of national workstreams and objectives (HLOs and specialty specific) with strategic oversight of research activity within the geography of CRN - West of England in terms of: –Portfolio Balance, new studies, feasibility, industry trials –Performance Targets, support timely set up, support timely recruitment –People Skill mix, flexibility, resources, training 4

5. Management Model Division s 2 & 6 Division s 3 & 4 Division 5 Division 1 Maxine Taylor Senior RDM Workforce Development Martine Cross Senior RDM RM&G and Industry Lead Ruth Allen RDM Business Intelligence lead Chantal Sunter RDM PCPIE and Comms Lead Mary Perkins Chief Operating Officer

6. Specialty Responsibility 6 Cancer Maxine Taylor Division 1 Primary Care Oral & DentalMusculoskeletal AgeingPublic Health DermatologyHealth Services Research Martine Cross Division 5 ChildrenMental Health Reproductive Health & ChildbirthDeNDRoN GeneticsNeurology Haematology Chantal Sunter Divisions 3 & 4 DiabetesENTOpthalmology StrokeSurgeryGastroenterology CardiovascularCritical CareInjuries & Emergencies RenalRespiratoryInfectious Diseases Metabolic/endocrineHepatologyAnaesthesia, Post-operative medicine & Pain Ruth Allen Divisions 2 & 6

7. The Clinical Team Dr Steve Falk Clinical Director 6 Divisional Clinical Leads Prof Hugh Barr for Div 1 30 Specialty Leads Sub Specialty Leads Sue Taylor Network Consultant Nurse Clinical Research Teams

8. Imaging Adv. panel Screening, Prevention & Early Diagnosis CTRad (Radiotherapy) Psychosocial & Survivorship Teenage & Young Adult Teenage & Young Adult Palliative & Supportive Care Palliative & Supportive Care Biomarkers Adv. panel Primary Care Primary Care Consumer Liaison Group Breast Cancer CSG Breast Cancer CSG Lung Cancer CSG Lung Cancer CSG Upper GI Cancer CSG Upper GI Cancer CSG Colorectal Cancer CSG Colorectal Cancer CSG Kidney Cancer CSG Kidney Cancer CSG Bladder Cancer CSG Bladder Cancer CSG Testis Cancer CSG Testis Cancer CSG Gynae Cancer CSG Gynae Cancer CSG PPI Brain Tumours CSG Brain Tumours CSG Head & Neck CSG Head & Neck CSG Sarcoma CSG Sarcoma CSG Melanoma CSG Melanoma CSG Lymphoma CSG Lymphoma CSG Haematol. CSG Haematol. CSG Prostate Cancer CSG Prostate Cancer CSG Children’s Cancer & Leukaemia

9. Division 1 Clinical Lead Brain cancer H&N cancer Lung cancer Breast cancer Sarcoma Skin Cancer Children/young people Upper GI cancer Colorectal cancer Urological cancer Gynae cancer Haem/lymphoma Pall/Supportive & Psychosocial 13 LCRN Subspecialty Leads: LCRN (x15) Clin Director LCRN Exec Board COO Division 1 RDM Research Delivery Teams Partnership Group Clin. Advisory Group [ +/- other clinical roles]

10. NIHR CRN High Level Objectives Set up as fast as you can Recruit as many and as fast as you can All organisations Commercial and non commercial Specialty specific objectives

11. How important is cancer on our patch? Cancer incidence 9544 242 recruiting studies £2 million (16%) Funding per incident case approx £220 Funding per recruit £800 Exceeded both recruitment targets for last 2 years Largest non commercial portfolio Benefit from continued good national and international links

12. 12 * *Primary care target 9224

13. Haem onc recruitment ytd by Trust: Interventional and non-interventional studies 13

14. Haem onc recruitment ytd by Trust and study 14

15. Lymphoma recruitment ytd by Trust and study 15

16. Contact details Maxine.taylor@nihr.ac.uk Hugh.barr@glos.nhs.uk http://csg.ncri.org.uk/portfolio-maps/ http://www.crn.nihr.ac.uk/can-help/funders- academics/nihrcrn-portfolio/http://www.crn.nihr.ac.uk/can-help/funders- academics/nihrcrn-portfolio/ 16

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