From: Prevalence of Antineutrophil Cytoplasmic Antibodies in a Large Inception Cohort of Patients with Connective Tissue Disease Ann Intern Med. 1997;126(11):866-873.

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From: Prevalence of Antineutrophil Cytoplasmic Antibodies in a Large Inception Cohort of Patients with Connective Tissue Disease Ann Intern Med. 1997;126(11):866-873. doi:10.7326/0003-4819-126-11-199706010-00003 Figure Legend: Testing algorithm used for the final determination of the presence of antiproteinase 3 antibodies (anti-PR3).⊕ = positive final interpretation; ⊖ = negative final interpretation; ELISA = enzymelinked immunosorbent assay; P-ANCA = perinuclear pattern of staining for antineutrophil cytoplasmic antibodies. Date of download: 9/21/2017 Copyright © American College of Physicians. All rights reserved.

From: Prevalence of Antineutrophil Cytoplasmic Antibodies in a Large Inception Cohort of Patients with Connective Tissue Disease Ann Intern Med. 1997;126(11):866-873. doi:10.7326/0003-4819-126-11-199706010-00003 Figure Legend: Results of sandwich enzyme-linked immunosorbent assay (ELISA) for antiproteinase 3 antibodies (anti-PR3) in the serum of patients with connective tissue disease.The sample size (n) for each study group is given. A logarithmic scale is used for the ELISA results; the dotted line represents the positivity cutoff for the sandwich anti-PR3 ELISA (20.0 U). All measurements on or above the dotted line are considered to indicate positivity for anti-PR3. APS = the antiphospholipid syndrome; BD = blood-donor controls; EUCTD = early undifferentiated connective tissue disease; MPO+ = controls with vasculitis positive for antimyeloperoxidase antibodies; PM/DM = inflammatory myositis; PR3+ = controls with vasculitis positive for anti-PR3; PS = scleroderma; RA = rheumatoid arthritis; SJ = the Sjogren syndrome; SLE = systemic lupus erythematosus. Date of download: 9/21/2017 Copyright © American College of Physicians. All rights reserved.

From: Prevalence of Antineutrophil Cytoplasmic Antibodies in a Large Inception Cohort of Patients with Connective Tissue Disease Ann Intern Med. 1997;126(11):866-873. doi:10.7326/0003-4819-126-11-199706010-00003 Figure Legend: Results of direct enzyme-linked immunosorbent assay (ELISA) for antiproteinase 3 antibodies (anti-PR3) in the serum of patients with connective tissue disease.The sample size (n) for each study group is given. A logarithmic scale is used for the ELISA results; the dotted line represents the positivity cutoff for the direct anti-PR3 ELISA (5.0 U). All measurements on or above the dotted line are considered to indicate positivity for anti-PR3. APS = the antiphospholipid syndrome; BD = blood-donor controls; EUCTD = early undifferentiated connective tissue disease; MPO+ = controls with vasculitis positive for antimyeloperoxidase antibodies; PM/DM = inflammatory myositis; PR3+ = controls with vasculitis positive for anti-PR3; PS = scleroderma; RA = rheumatoid arthritis; SJ = the Sjogren syndrome; SLE = systemic lupus erythematosus. Date of download: 9/21/2017 Copyright © American College of Physicians. All rights reserved.

From: Prevalence of Antineutrophil Cytoplasmic Antibodies in a Large Inception Cohort of Patients with Connective Tissue Disease Ann Intern Med. 1997;126(11):866-873. doi:10.7326/0003-4819-126-11-199706010-00003 Figure Legend: Results of direct enzyme-linked immunosorbent assay (ELISA) for antimyeloperoxidase antibodies (anti-MPO) in the serum of patients with connective tissue disease.The sample size (n) for each study group is given. A logarithmic scale is used for the ELISA results; the dotted line represents the positivity cutoff for the direct anti-MPO ELISA (2.8 U). All measurements on or above the dotted line are considered to indicate positivity for anti-MPO. APS = the antiphospholipid syndrome; BD = blood-donor controls; EUCTD = early undifferentiated connective tissue disease; MPO+ = controls with vasculitis positive for anti-MPO; PM/DM = inflammatory myositis; PR3+ = controls with vasculitis positive for antiproteinase 3 antibodies; PS = scleroderma; RA = rheumatoid arthritis; SJ = the Sjogren syndrome; SLE = systemic lupus erythematosus. Date of download: 9/21/2017 Copyright © American College of Physicians. All rights reserved.

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