1. Lymphatic System and Immunity Chapter 16

2. The lymphatic system is closely associated with the cardiovascular system It includes a network of vessels that circulate body fluids

3. Figure 16.5 page 427 Lymphatic Capillaries Microscopic, closed- ended tubes that assist in the transport of fluids

4. Lymph The fluid inside a lymphatic capillary

5. Lymphatic Vessels Formed by the merging of lymphatic capillaries They have valves that help prevent backflow of lymph

6. Lymph Nodes Formed by the merging of lymphatic vessels Lymphatic Trunk Drain lymph

7. Collecting & Thoracic Ducts Receive and get rid of lymph ******************

8. TISSUE FLUID & LYMPH Tissue fluid originates from blood plasma and is composed of water and dissolved substances

9. FUNCTION OF LYMPH *Carries protein molecules that leak out of the blood capillaries, back to the bloodstream

10. *Transports foreign particles (bacterial cells & viruses) that may have entered the tissue fluids, to the lymph nodes ******************

11. LYMPH NODES Lymphocyte A type of white blood cell that is important to immunity

12. Hilum The indented region of a lymph node through which the blood vessels and nerves connect with the structure

13. Nodule Dense mass of lymphocytes

14. Lymph Sinuses Spaces within the node through which lymph circulates ******************

15. THYMUS & SPLEEN Thymus A glandular organ located in the mediastinum behind the sternum and between the lungs

16. It secretes a hormone called thymosin which is thought to stimulate the maturation of certain T lymphocytes

17. Spleen A large, glandular organ located in the upper left region of the abdomen ******************

18. BODY DEFENSES AGAINST INFECTION Infection Invasion of microorganisms into the tissue; leads to inflammation

19. Pathogens Agents that cause disease Immunity The condition that permits natural or acquired resistance to disease

20. NONSPECIFIC IMMUNITY Species Resistance Mechanical Barriers Against the entrance of infectious agents: skin, mucous membranes

21. Chemical Barriers Also prevent the entrance of disease: enzymes in various body fluids (tears, stomach acid)

22. Inflammation A response that occurs in the blood vessels and tissues in response to an injury or irritation (White blood cells group here)

23. SPECIFIC TYPES OF IMMUNITY Naturally acquired active immunity occurs when a person who has been exposed to a live pathogen…

24. …develops a disease and becomes resistant to that pathogen as a result of a primary immune response

25. Vaccine A substance that contains antigens and is used to stimulate the production of antibodies

26. Vaccines usually contain bacteria or viruses that have been killed or weakened so they cannot cause serious infection

27. This is considered Artificially acquired active immunity

28. ALLERGIC REACTIONS Involve antigens combining with antibodies

29. Likely to be excessive or violent and may cause tissue damage A delayed-reaction allergy results from repeated exposure to antigenic substances

30. Allergen A foreign substance capable of stimulating an allergic reaction

31. Allergic reactions may damage certain cells, which, in turn, release various chemicals

32. The released chemicals can cause hives, hay fever, asthma, eczema, or gastric disturbances

33. TRANSPLANTATION & TISSUE REJECTION If transplanted tissue is recognized/matched it will be accepted by the recipient’s cells ***********************

34. If the recipient’s cells see the tissue as foreign, the tissue will act against it and reject it