1. © 2010 Pearson Education, Inc. Lectures by Chris C. Romero, updated by Edward J. Zalisko PowerPoint ® Lectures for Campbell Essential Biology, Fourth Edition – Eric Simon, Jane Reece, and Jean Dickey Campbell Essential Biology with Physiology, Third Edition – Eric Simon, Jane Reece, and Jean Dickey Chapter 1 Introduction: Biology Today

2. We are living in a golden age of biology. Biology provides exciting breakthroughs changing our culture. –Molecular biology is solving crimes and revealing ancestries. –Ecology helps us address environmental issues. –Neuroscience and evolutionary biology are reshaping psychology and sociology. Biology and Society: Biology All Around Us © 2010 Pearson Education, Inc.

3. Figure 1.00

4. © 2010 Pearson Education, Inc. Biology is the scientific study of life. –Life is structured on a size scale ranging from the molecular to the global. –Biology’s scope stretches across the enormous diversity of life on Earth. –Life had to have been given a “scientific” description, so the following characteristics encompass that description. THE SCOPE OF LIFE The Properties of Life

5.  a  Order Figure 1.1ba

6.  b  Regulation Figure 1.1bb

7.  c  Growth and development Figure 1.1bc

8.  d  Energy utilization Figure 1.1bd

9.  e  Response to the environment Figure 1.1be

10.  f  Reproduction Figure 1.1bf

11.  g  Evolution Figure 1.1bg

12. © 2010 Pearson Education, Inc. Biologists explore life at levels ranging from the biosphere to the molecules that make up cells. Life at Its Many Levels

13. Biosphere Ecosystems Communities Populations Figure 1.2-1

14. Biosphere Ecosystems Communities Populations Organisms Organ Systems and Organs Tissues Figure 1.2-2

15. Biosphere Ecosystems Communities Populations Organisms Organ Systems and Organs Tissues Cells Organelles Molecules and Atoms Atom Nucleus Figure 1.2-3

16. Figure 1.2a Biosphere

17. © 2010 Pearson Education, Inc. Ecosystems Each organism interacts continuously with its environment. –Organisms interact continuously with the living and nonliving factors in the environment. –The interactions between organisms and their environment take place within an ecosystem. The dynamics of any ecosystem depend on two main processes: –Cycling of nutrients –Flow of energy

18. Inflow of light energy Chemical energy  food  Cycling of nutrients Consumers  animals  Producers  plants and other photosynthetic organisms  Decomposers  in soil  Loss of heat energy ECOSYSTEM Figure 1.3

19. © 2010 Pearson Education, Inc. Cells and Their DNA The cell is the lowest level of structure that can perform all activities required for life. –All organisms are composed of cells.

20. © 2010 Pearson Education, Inc. We can distinguish two major types of cells: –Prokaryotic –Eukaryotic

21. © 2010 Pearson Education, Inc. The prokaryotic cell is simpler and smaller and contains no organelles. Bacteria have prokaryotic cells.

22. © 2010 Pearson Education, Inc. The eukaryotic cell is larger, more complex, and contains organelles. The nucleus is the largest organelle in most eukaryotic cells. Plants and animals are composed of eukaryotic cells. Eukaryotic cells have membrane-bound organelles

23. Prokaryotic cell Nucleoid region Organelles Nucleus Colorized TEM (bacterium) Simpler structure Smaller DNA concentrated in nucleoid region, which is not enclosed by membrane Lacks most organelles Eukaryotic cell Larger More complex structure Nucleus enclosed by membrane Contains many types of organelles Figure 1.4

24. © 2010 Pearson Education, Inc. All cells use DNA as the chemical material of genes. –Genes are the units of inheritance that transmit information from parents to offspring. The language of DNA contains just four letters: –A, G, C, T The entire book of genetic instructions that an organism inherits is called its genome.

25. The four chemical building blocks of DNA A DNA molecule Figure 1.5

26. © 2010 Pearson Education, Inc. Genetic engineering and biotechnology have allowed us to manipulate the DNA and genes of organisms. Bacteria can make insulin because a gene for insulin production was transplanted into their DNA.

27. Figure 1.6

28. © 2010 Pearson Education, Inc. Life in Its Diverse Forms Diversity is the hallmark of life. –The diversity of known life includes 1.8 million species. –Estimates of the total diversity range from 10 million to over 100 million species.

29. © 2010 Pearson Education, Inc. Grouping Species: The Basic Concept Biodiversity can be beautiful but overwhelming. Taxonomy is the branch of biology that names and classifies species. –It formalizes the hierarchical ordering of organisms.

30. Figure 1.7

31. © 2010 Pearson Education, Inc. The Three Domains of Life The three domains of life are –Bacteria –Archaea –Eukarya

32. © 2010 Pearson Education, Inc. Bacteria and Archaea have prokaryotic cells.

33. DOMAIN BACTERIA DOMAIN ARCHAEA DOMAIN EUKARYA Kingdom Plantae Kingdom Fungi Kingdom Animalia Protists (multiple kingdoms) TEM Colorized TEM LM Figure 1.8

34. DOMAIN BACTERIA DOMAIN ARCHAEA TEM Colorized TEM Figure 1.8a

35. DOMAIN EUKARYA Kingdom Plantae Kingdom Fungi Kingdom Animalia Protists  multiple kingdoms  LM Figure 1.8b

36. Domain Bacteria Colorized TEM Figure 1.8ba

37. Domain Archaea TEM Figure 1.8bb

38. Kingdom Plantae Figure 1.8bc

39. Kingdom Fungi Figure 1.8bd

40. Kingdom Animalia Figure 1.8be

41. Protists  multiple kingdoms  LM Figure 1.8bf

42. © 2010 Pearson Education, Inc. Eukarya includes –Kingdom Plantae –Kingdom Fungi –Kingdom Animalia –Protists (multiple kingdoms) Protists are generally single celled. Most plants, fungi, and animals are multicellular.

43. © 2010 Pearson Education, Inc. These three multicellular kingdoms are distinguished by how they obtain food. –Plants produce their own sugars and other foods by photosynthesis. –Fungi are mostly decomposers, digesting dead organisms. –Animals obtain food by eating and digesting other organisms.

44. © 2010 Pearson Education, Inc. Unity in the Diversity of Life Underlying the diversity of life is a striking unity, especially at the lower levels of structure. –For example, all life uses the genetic language of DNA. Biological evolution accounts for this combination of unity and diversity.

45. © 2010 Pearson Education, Inc. EVOLUTION: BIOLOGY’S UNIFYING THEME The history of life is a saga of a restless Earth billions of years old. –Fossils document this history.

46. Figure 1.9

47. © 2010 Pearson Education, Inc. Life evolves. –Each species is one twig of a branching tree of life extending back over 3 billion years. –Species that are very similar, such as brown bears and polar bears, share a more recent common ancestor.

48. Ancestral bear Common ancestor of polar bear and brown bear Giant panda Spectacled bear Sloth bear Sun bear American black bear Asiatic black bear Polar bear Brown bear 30252015105 Millions of years ago Figure 1.10

49. © 2010 Pearson Education, Inc. The Darwinian View of Life The evolutionary view of life came into focus in 1859 when Charles Darwin published The Origin of Species.

50. Figure 1.11

51. Figure 1.11a

52. Figure 1.11b

53. © 2010 Pearson Education, Inc. Darwin’s book developed two main points: –Descent with modification – this means that every subsequent generation of living thing, showed features of adapting to the environment! This is the most puzzling and fascinating features of life. –Natural selection - this is a THEORY that generally states that the fittest organism survives to reproduce while those who are less capable, die. –Question: what do you think about modern medicine saving 1 pound babies on life support for 4-6 months until they are a “viable” organism? –Are we saving the weak to then procreate and create more and more weak members of the species?

54. © 2010 Pearson Education, Inc. Natural Selection Darwin was struck by the diversity of animals on the Galápagos Islands. He thought that adaptation to the environment and the origin of new species were closely related processes. –As populations separated by a geographic barrier adapted to local environments, they became separate species.

55. © 2010 Pearson Education, Inc. Darwin’s Inescapable Conclusion Darwin synthesized the theory of natural selection from two observations that were neither profound nor original. –Others had the pieces of the puzzle, but Darwin could see how they fit together.

56. © 2010 Pearson Education, Inc. Observation 1: Overproduction and competition Observation 2: Individual variation Conclusion: Unequal reproductive success –It is this unequal reproductive success that Darwin called natural selection. –The product of natural selection is adaptation. Natural selection is the mechanism of evolution.

57. Population with varied inherited traits Elimination of individuals with certain traits Reproduction of survivors Increasing frequency of traits that enhance survival and reproductive success Figure 1.12

58. © 2010 Pearson Education, Inc. Observing Artificial Selection Artificial selection is the selective breeding of domesticated plants and animals by humans. In artificial selection, humans do the selecting instead of the environment.

59.  a  Vegetables descended from wild mustard Cabbage from terminal bud Brussels sprouts from lateral buds Kohlrabi from stem Kale from leavesBroccoli from flower and stems Cauliflower from flower clusters Wild mustard Figure 1.13a

60.  b  Domesticated dogs descended from wolves Domesticated dogsGray wolves Figure 1.13b

61. © 2010 Pearson Education, Inc. Observing Natural Selection There are many examples of natural selection in action. –Galápagos finches change beak size depending upon the size and shape of available seeds. –Antibiotic-resistant bacteria have evolved in response to the overuse of antibiotics.

62. © 2010 Pearson Education, Inc. Darwin’s publication of The Origin of Species fueled an explosion in biological research. –Evolution is one of biology’s best demonstrated, most comprehensive, and longest lasting theories. –Evolution is the unifying theme of biology.

63. © 2010 Pearson Education, Inc. THE PROCESS OF SCIENCE The word science is derived from a Latin verb meaning “to know.” –Science is a way of knowing. –Science developed from people’s curiosity about themselves and the world around them.

64. © 2010 Pearson Education, Inc. Discovery Science Science seeks natural causes for natural phenomena. –This limits the scope of science to the study of structures and processes that we can observe and measure.

65. © 2010 Pearson Education, Inc. Verifiable observations and measurements are the data of discovery science. –In biology, discovery science enables us to describe life at its many levels.

66. Figure 1.14a

67. Figure 1.14b

68. © 2010 Pearson Education, Inc. Discovery science can lead to important conclusions based on a type of logic called inductive reasoning. –An inductive conclusion is a generalization that summarizes many concurrent observations.

69. © 2010 Pearson Education, Inc. Hypothesis-Driven Science As a formal process of inquiry, the scientific method consists of a series of steps. –The key element of the scientific method is hypothesis-driven science.

70. © 2010 Pearson Education, Inc. A hypothesis is a proposed explanation for a set of observations—an idea on trial. Once a hypothesis is formed, an investigator can use deductive logic to test it. –In deduction, the reasoning flows from the general to the specific.

71. © 2010 Pearson Education, Inc. In the process of science, the deduction usually takes the form of predictions about experimental results. –Then the hypothesis is tested by performing an experiment to see whether results are as predicted. –This deductive reasoning takes the form of “If…then” logic.

72. Observation: My flashlight doesn’t work. Question: What’s wrong with my flashlight? Prediction: If I replace the batteries, the flashlight will work. Experiment: I replace the batteries with new ones. Experiment supports hypothesis; make additional predictions and test them. Experiment does not support hypothesis; revise hypothesis or pose new one. Revise Hypothesis: The flashlight’s batteries are dead. Figure 1.15-3

73. The Process of Science: Is Trans Fat Bad for You? One way to better understand how the process of science can be applied to real-world problems is to examine a case study, an in- depth examination of an actual investigation. © 2010 Pearson Education, Inc.

74. Dietary fat comes in different forms. Trans fat is a non-natural form produced through manufacturing processes. Trans fat –Adds texture –Increases shelf life –Is inexpensive to prepare

75. © 2010 Pearson Education, Inc. A study of 120,000 female nurses found that high levels of trans fat nearly doubled the risk of heart disease.

76. © 2010 Pearson Education, Inc. A hypothesis-driven study published in 2004 –Started with the observation that human body fat retains traces of consumed dietary fat. –Asked the question: Would the adipose tissue of heart attack patients be different from a similar group of healthy patients? –Formed the hypothesis that healthy patients’ body fat would contain less trans fat that the body fat in heart attack victims.

77. © 2010 Pearson Education, Inc. The researchers set up an experiment to determine the amounts of fat in the adipose tissue of 79 patients who had a heart attack. They compared these patients to the data for 167 patients who had not had a heart attack. This is an example of a controlled experiment, in which the control and experimental groups differ only in one variable—the occurrence of a heart attack.

78. © 2010 Pearson Education, Inc. The results showed significantly higher levels of trans fat in the bodies of the heart attack patients.

79. Heart attack patients Control group Trans fats in adipose tissue  g trans fat per 100 g total fat  2.0 1.5 1.0 0.5 0 1.77 1.48 Figure 1.16

80. © 2010 Pearson Education, Inc. Theories in Science What is a scientific theory, and how is it different from a hypothesis? –A theory is much broader in scope than a hypothesis. –Theories only become widely accepted in science if they are supported by an accumulation of extensive and varied evidence.

81. © 2010 Pearson Education, Inc. Scientific theories are not the only way of “knowing nature.” Science and religion are two very different ways of trying to make sense of nature.

82. © 2010 Pearson Education, Inc. The Culture of Science Scientists build on what has been learned from earlier research. –They pay close attention to contemporary scientists working on the same problem. Cooperation and competition characterize the scientific culture. –Scientists check the conclusions of others by attempting to repeat experiments.

83. Figure 1.17

84. © 2010 Pearson Education, Inc. Science, Technology, and Society Science and technology are interdependent. –New technologies advance science. –Scientific discoveries lead to new technologies. –For example, the discovery of the structure of DNA about 50 years ago led to a variety of DNA technologies.

85. © 2010 Pearson Education, Inc. –Technology has improved our standard of living in many ways, but it is a double-edged sword. –Technology that keeps people healthier has enabled the human population to double to nearly 7 billion in just the past 40 years. –The environmental consequences of this population growth may be devastating.

86. Figure 1.18

87. © 2010 Pearson Education, Inc. Evolution Connection: Evolution in Our Everyday Lives Antibiotics are drugs that help fight bacterial infections. When an antibiotic is taken, most bacteria are typically killed. Those bacteria most naturally resistant to the drug can still survive. Those few resistant bacteria can soon multiply and become the norm and not the exception.

88. © 2010 Pearson Education, Inc. The evolution of antibiotic-resistant bacteria is a huge problem in public health. Antibiotics are being used more selectively. Many farmers are reducing the use of antibiotics in animal feed.

89. Colorized SEM Figure 1.19

90. Order Regulation Growth and development Energy utilization Response to the environment ReproductionEvolution Figure UN1-1

91. Domain Bacteria Domain Archaea Domain Eukarya Three kingdoms PlantaeFungiAnimaliaProtists Prokaryotes Eukaryotes Life Figure UN1-2

92. Observations Conclusion Overproduction and competition Individual variation Unequal reproductive success  natural selection  Figure UN1-3

93. ObservationQuestionHypothesisPredictionExperiment Revise and repeat Figure UN1-4

94. No reward Average time to complete maze  min  Day Food reward Key 25 20 15 10 5 0 0123456 Figure UN1-5