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Blood Smear.

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Presentation on theme: "Blood Smear."— Presentation transcript:

1 Blood Smear

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6 This peripheral blood smear from a patient with essential thrombocythemia shows increased numbers of platelets, including some large forms. (H and E, 400x)

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9 Malaria

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11 Atypical, or reactive, lymphocytes

12 Acanthocytes (red arrow) and schizocytes (black arrow) in a canine blood smear

13 Keratocytes in a canine blood smear

14 Band neutrophil

15 Vacuolated monocyte

16 Lymphocyte with azurophilic granules

17 Hypersegmentation

18 Toxic granulation

19 Döhle body

20 Platelets - finger-stick

21 Giant platelet

22 Nucleated Red Blood Cells

23 Macrocytic Red Blood Cells Compared to Normal Red Blood Cells

24 Promyelocyte

25 Segmented Neutrophil, Metamyelocyte, Band

26 Sickle Cell Anemia

27 Pernicious Anemia

28 Plasma cell

29 Hairy cell

30 Larger than average RBCs are macrocytic (left), while those smaller than average are microcytic (right).

31 Pale cells (central pallor >1/3 dia) are referred to as hypochromic (right), while cells without central pallor are called hyperchromic (left).

32 SCHISTOCYTES

33 TARGETS

34 OVALOCYTES

35 STOMATOCYTES

36 SPHEROCYTES

37 ACANTHOCYTES

38 BURR CELLS

39 Elliptocytosis

40 Tear Drop Cells

41 Rouleaux Formation

42 Basophilic stippling

43 Howell-Jolly Bodies

44 Platelet Clumping

45 Auer Rods

46 With iron deficiency anemia, the MCV of the red blood cells is decreased, the zone of central pallor is increased, and the overall sizes and shapes of the RBC's are less uniform (increased anisocytosis and poikilocytosis ).

47 Heinz bodies (red arrows) and nucleated red blood cells (purple arrows) in scattered erythrocytes of a dog with zinc toxicosis (Dog, blood smear, Wright-Leishman stain).

48 Spherocytes (red arrows) and nucleated red blood cells (purple arrows) in the blood smear of a dog with zinc toxicosis (Dog, blood smear, Wright-Leishman stain).

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53 Can you identify the segmented neutrophil, band neutrophil, lymphocyte, monocyte, eosinophil, basophil, and platelet in this image?

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56 This is a picture of a blood smear as seen by a microscope
This is a picture of a blood smear as seen by a microscope.  The red cells are the smaller, more numerous round objects. There are two white cells in the middle (they are blue because they have been stained).

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66 Picture of bone marrow smear (control); Normal granulocytes and erythroblasts are evident.

67 Acute lymphoid leukemia (ALL); There is a marked proliferation of small lymphoblasts.

68 Acute myeloid leukemia (AML); There is a marked proliferation of large myeloblasts

69 Chronic myeloid leukemia (CML); There is a marked proliferation of granulocytes at various stages of maturation.

70 AML (M0)

71 AML (M1)

72 AML (M2)

73 AML (M3)

74 AML (M4)

75 AML (M5)

76 AML (M5) -alpha-naphthyl butyrate esterase and chloroacetate esterase stains

77 AML (M6) -PAS stain

78 AML (M6)

79 AML (M7)

80 Chronic myelocytic leukemia

81 Chronic lymphocytic leukemia (CLL)

82 Acute Lymphoblastic Leukemia (ALL)

83 Acute lymphocytic leukemia (ALL)

84 ALL-L1

85 ALL-L2 

86 ALL-L3

87 thanks


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