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The Complement Cascade The Classical Pathway Next
Complement: The Classical Pathway AgAb Antibody binds to antigen C1q C1q binds to antibody/antigen complex Next
Complement: The Classical Pathway C1q-Ab-Ag
Complement: The Classical Pathway C1r-C1s C1q-Ab-Ag C1r-C1s C1q/antibody/antigen complex activates C1r (bound to C1s) Next
Activated C1r cleaves C1r/C1s, Complement: The Classical Pathway C1r-C1s C1q-Ab-Ag C1r-C1s releasing Active C1s C1s Next
Complement: The Classical Pathway C1r-C1s C1q-Ab-Ag C1r-C1s C1s C4 C1s cleaves C4 to C4a and C4b C4a C4b Next
Complement: The Classical Pathway C1r-C1s C1q-Ab-Ag C1r-C1s C1s C4 C4b binds to C2 C4b C4a C2 C4b.2 Next
Complement: The Classical Pathway C1r-C1s C1q-Ab-Ag C1r-C1s C1s C4 C4a C4b.2 C4b.2b C2a producing C4b.2b and C2a Next C1s cleaves C2
Complement: The Classical Pathway C4b.2b is termed the Classical C3 Convertase C4b.2b cleaves C3 to produce C3b (C3a is released) C3b is the first molecule of the Terminal Pathway Next
Complement: The Classical Pathway C1r-C1s C1q-Ab-Ag C1r-C1s C1s C4 C4a C4b.2C4b.2b C2a C3 C3a C3b producing C3a and C3b Cb4.2b cleaves C3 (Click Here)
Complement: The Classical Pathway C1r-C1s C1q-Ab-Ag C1r-C1s C1s C4 C4a C4b.2b C2a C3 C3a C3b C5C5b C5a C4b.2
Complement: The Classical Pathway C1r-C1s C1q-Ab-Ag C1r-C1s C1s C4 C4a C4b.2b C2a C3 C3a C3b C5C5b C5a C4b.2 C6 C5b.6 C7 C5b.6.7 C8 C5b C9n C5b n
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1 5.5 and 5.6 Multiply Polynomials. 2 Square of a Binomial Examples: 1. Multiply: (2x + 2) 2. (a + b) 2 = (a + b)(a + b) = a 2 + 2ab + b 2 = (2x) 2 +
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© 2012 Pearson Education, Inc. Lecture by Edward J. Zalisko PowerPoint Lectures for Campbell Biology: Concepts & Connections, Seventh Edition Reece, Taylor,
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Complement system -main humoral mechanism of nonspecific immunity - > 40 glykoproteins - blood - blood - on the surface of immune cells - on the surface.
AP Biology Chapter 11 Cell Communication AP Biology Gap junctions between animal cells Cell-Cell Communication Animal cells use gap junctions to send.
ANTIGEN-ANTIBODY INTERACTION LECTURER: DAVID. OBJECTIVES.
Instructions for ??????????????????????????? What you will make What you will need What to do
Aim: How to interpret potential energy diagrams? A catalyst provides an alternate reaction pathway, which has a lower activation energy than an uncatalyzed.
1 Chapter 29 Growth Factors Copyright © 2012, American Society for Neurochemistry. Published by Elsevier Inc. All rights reserved.
Antibody Production The blood contains two types of white blood cell or leucocyte Phagocytes (macrophages) ingest bacteria by endocytosis Lymphocytes.
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Flow cytometry gel electrophoresis immunoprecipitation (IP) immunoblotting microscopy immunofluorescence (IFA) electron microscopy ELISA Analytical Techniques.
Specific Defenses of the Host: The Immune Response Immunogen: A substance that induces a specific immune response Antigen (Ag): A substance that reacts.
Solution Formation. Heat of Solution The Heat of Solution is the amount of heat energy absorbed (endothermic) or released (exothermic) when a specific.
Cell Signaling A.Types of Cell Signaling B.Intracellular Receptor Signaling: Steroid Hormones C.Cell Surface Receptors: Types D. Cell Surface Receptors:
IN ON UNDER IN FRONT OF BEHIND BETWEEN NEXT TO NEAR ON THE LEFT OF ON THE RIGHT OF.
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Rhetorical Précis. First lets try an analogy to help understand.
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