1. Introduction to Research at WRNMMC
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Walter Reed National Military Medical Center Directorate for Professional Education Department of Research Programs
Introduction to Research at WRNMMC
Marina Borovok, PhD
Head of Research Education,
Department of Research Programs,
WRNMMC
September 2011
Welcome to the first offering of our new introduction to research course!
We hope this will give you a feeling for how to navigate the research process in general, and specifically here at NNMC.
I am Dr Jeff Lenert, the head of Clinical Investigations here at NNMC and we want you to be able to put some faces with the names of people here who can help you generate and complete your research projects.
Thanks for your interest and thanks for coming. I hope it is worthwhile.
Toward that end the content of the course was developed in response to surveys undertaken over the past year asking what people with an interest in research wanted to learn more about. We can further tailor and improve the content if you would please give feedback on the course directly as well as by filling out your evaluation forms.
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2. Disclosure Statement :
This CE/CME activity does not have commercial support, and has no conflicts of interest.
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3. 2011
Learning Objectives
Describe clinical research and the research process steps
Discus research at WRNMMC and it’s unique opportunities.
3. Know about research support available at WRNMMC.
Recognize IT tools that support research collaboration and communication from anywhere at any time.
In my presentation I’d like to accomplish the following…
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4. LO 1: Describe clinical research and the research process steps
Before you start your research at WRNMMC, you need to do the following THREE steps:
Step 1: Obtaining a DKO/AKO account
Step 2: Registering with IRBNet, e-portal for publications and protocol submission.
Step 3: Completion of CITI training
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5. Research Cue Card
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6. Step 1: Obtaining a DKO/AKO account
AKO/DKO platform for research purposes What is AKO? Army Knowledge Online (AKO) is the world's largest and secure electronic platform. AKO is currently serving over 2.26 million users. What is DKO? Defense Knowledge Online (DKO) is an information sharing network required by the Department of Defense to support secure access to information (portal). DKO is using AKO as a platform.
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7. MANY Benefits of DKO 1. Universal Email in the .mil environment.
2. Virtual workspace (telework) any time especially in times of national disaster (Sept 11, Pandemic, etc) or exercises (example: DCO)
3. Virus and Spam scanning for over 3 Billion messages per year.
4. Provides access to over 2K free training courses via JKO, etc.
5. Use AKO/DKO credentials to access MyPay, Tricare Online and over 1,200 other DOD applications that use AKO/DKO SSO services.
6. If you have Internet access, you can access AKO/DKO securely from anywhere at any time
7. Centralized Helpdesk (open 24/7) supporting 2.26M users and over 1,200 DoD applications.
8. Use AKO/DKO Portal as a Virtual Thumb Drive ensuring files and folders needed are available regardless of location.
9. Social capabilities such as milSUITE allow you to find new people working on similar projects or with similar interests.
10. Communicate with anyone in DoD via IM, , video messaging.
11. Over 50K deployed US Armed Forces members use AKO/DKO while deployed to many places worldwide.
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8. AKO/DKO platform for research purposes The Defense Medical Research Network (DMRN)
For better management of research processes, The Defense Medical Research Network (DMRN) was created. It is a DoD-wide web-based networking solution for all your research management, compliance and oversight needs. Located on AKO/DKO platform at:
IRBNet
IRBNet is the industry leading software, a robust set of electronic tools supporting the management, submission, review and oversight of our research protocols.
IRBNet entry is available through DMRN page that located on AKO/DKO site.
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9. Step 1: Obtaining a DKO/AKO account
Go to the Defense Medical Research Network (DMRN)page on DKO/AKO website at
Cue Card Reference:
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10. Step 1: Obtaining a DKO/AKO account (cont.)
Login using your AKO/DKO username and password
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11. Step 1: Obtaining a DKO/AKO account (cont.)
You are at the DMRN site at
Click on the IRBNet Entry button
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12. Step 1: Obtaining a DKO/AKO account (cont.)
Instructions are at the RCRS website
Questions?
Contact Ms. Dale Gregory
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13. Instructions are at the RCRS website
Step 2: Registering with IRBNet, e-portal for publications and protocol submission.
Cue Card Reference:
Instructions are at the RCRS website
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14. Step 2: Registering with IRBNet, e-portal for publications and protocol submission (cont.)
Questions?
Please contact Mr. Luis Calvo at
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15. Step 3: Completion of CITI training
Cue Card
Reference:
Principal Investigators, Associate Investigators, Research Staff, as well as anyone coming into contact with Human Subjects or involved with the consent process or study design are required to complete this course.
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16. Step 3: Completion of CITI training
The course is available at
First Time Users need to register at
Questions?
Contact Dr. Marina Borovok
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17. Now you are done with the registrations and training. What is next?
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18. Next steps: 4-5
The entire research writing process can be divided into easily manageable and clear steps:
STEP 4: Develop a Research Question
Select a topic
Discuss Research Ideas
Find Sources to support your ideas
STEP 5: Submit your proposal via
Proposal Approval
Funding (if needed)
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19. Step 4: Develop Research Question Good research question: could the "FINER" criteria be applied to it? F- Feasible.  Is the question answerable?  Do you have access to all the materials you will need to do the study?  Do you have access to enough subjects?  Will you have enough time and money?  Do you have the expertise to do this study or can you collaborate with someone who does? I- Interesting.  The question has to be interesting to the investigator, but should also be interesting to others. N- Novel.  Has this study been done before?  Does it add to the current body of medical knowledge? E- Ethical.  Risk/benefit ratio? Can the study be done with a minimal risk?  Will an IRB approve the study? R- Relevant.  Will it further medical science?  Will the results change clinical practice, health policy or point towards further avenues of research? If your question fails on any one of these 5 criteria, it is probably not worth putting much effort into.
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20. STEP 4: Good research question (cont.)
Readings:
Designing clinical research: an epidemiologic approach, 3rd ed., by Stephen B. Hulley, et.al. Lippincott Williams & Wilkins, 2007 ISBN: ;
Research begins with the question.
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21. Step 4: Research topic selection
Cue Card Reference: In order to do that you need to consult with your Department Chair/Supervisor/Mentor. Need help to choose your Mentor? Please contact Dr. Marina Borovok at
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22. Step 4: Research topic selection (cont.) In case if you need HELP
Choose your mentor, and ask him/her to help.
INTERNET Web resource :
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23. Protocol Outreach Program to discuss research ideas and roadmap:
Step 4: Research topic selection (cont.) New: Protocol Outreach Program
Protocol Outreach Program to discuss research ideas and roadmap:
Clinician, statistician, regulatory reviewer, laboratory scientist
45 min appointments for research ideas and roadmap.
More information will be provided by Dr. Klote (Module 6), and
Dr. Bernstein (Module 7).
To schedule an appointment
please contact Ms. Dale Gregory at
, or
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24. Step 5: Protocol submission via
Cue Card Reference:
Submission instructions are available on the IRBNet portal,
under Forms and Templates.
Questions?
Contact DRP
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25. Next steps are: Proposal Approval (SRP,IRB approval), Funding (if needed).
These steps will be successful if you worked on the Research Protocol with help of the WRNMMC specialists
(Step 4)
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26. Research Funding
Information on Research Funding is provided By Dr. Kaminsky (Day 2, Module 9).
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27. IMPORTANT TO REMEMBER !!! Cue Card Reference:
You may not begin your research until
you have received
an IRB Approval and Approval Letter
from the Commander, WRNMMC.
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28. The National Capital Region Military Medical Centers POCs:
Walter Reed National Military Medical Center DRP (WRNMMC) , Malcolm Grow Medical Center (MGMC), IRB Office Cheryl James The Uniformed Services University (USU), Research Office Maggie Pickerel
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29. Questions?
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30. LO 2: Discus research at WRNMMC and it’s unique opportunities
WRNMMC’s goal remains to promote excellence in health care and militarily relevant research and human subject protection.
Department of Research Programs (DRP)
Human subject protection, research compliance and integrity; research administration, support, funding, publication and education.
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31. Current research efforts at WRNMMC are ongoing:
Research at WRNMMC
Current research efforts at WRNMMC are ongoing:
head injury/TBI, stroke,
colon, breast cancer, leukemia and lymphoma,
investigational chemotherapy,
virtual colonoscopy,
diabetes management,
infectious disease,
dental imaging.
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32. Open Protocols at WRNMMC
List is available on the Intranet at:
Go to the Department of Research programs (DRP)) Intranet site at
and click on Open Protocols
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33. Questions?
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34. LO 3: Know about research support available at WRNMMC.
WRNMMC Research Resources Research Integrity Resources Department of Research Programs (DRP), Darnall Biomedical Learning Resource Center Research Protocol/Publication Help, Education/Mentoring Resources, Protocol Outreach Program ICEBERG, IT tools.
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35. Research Integrity Resources
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It is a policy of WRNMMC that all personnel will uphold highest principles of ethics
promoting research integrity and the responsible conduct of research (RCR).
RCR RESOURCES (web links):
TEXT
On Being A Scientist, National Academy of Sciences Committee on the Conduct of Science, 3rd Ed.,
Also available on the web at
DVD “THE LAB”
an interactive educational DVD has been developed by ORI for education regarding research misconduct.
Also available on the web at
RCRS site at (under the RCRS links),
WEB RESOURCES PROVIDED ON THE DRP WEBSITE (INTRANET) at: (under DRPLinks):
RESEARCH INTEGRITY
THE LAB: Interactive Movie on Research Misconduct
AVOID PLAGIARISM: 26 Guidelines at a glance
Research Ethics Resources provided by The Navy Medicine Institute
On Being a Scientist: A Guide to Responsible Conduct in Research: Third Edition (2009)
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36. Research Integrity Resources (cont.)
ANTI-PLAGIARISM SOFTWARE TURNITIN
Web-based,
Free access available to the WRNMMC researchers.
Ask Ann Holman to help with Turnitin registration: ,
Example of report : slide # 64
RESEARCH INTEGRITY DISCUSSIONS
ETHICS ROUNDTABLE: FRIDAYS (once/month, )
By Darnall Biomedical Learning Resource Center (Formerly Stitt Library)
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37. Department of Research Programs (DRP) Cue Card Reference:
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38. DRP information DEPARTMENT OF RESEARCH PROGRAMS (DRP)
Bldg. 17, 3rd floor, suite 3C
DRP Chief LTC Klote, MD, MC
(no voic )
Questions: , or
DRP Intranet
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39. Darnall Biomedical Learning Resource Center (DBLRC)
Bldg. 1, 3 rd floor, room 3458, ph
Hours Monday-Thursday   Friday                   
Online Access is available via Athens.
Athens Registration :
Ask Ann Holman to help with Athens registration ,
After Hours Access is available Contact Ann Holman at
or visit the Circulation Desk to sign up for an access account,
and we'll contact you when your card is ready. 
Library Access Card
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40. Darnall Biomedical Learning Resource Center (DBLRC)
Intranet Stitt Internet Questions:
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41. Research Protocol/Publication Help
*Literature Search:
Comprehensive DB specialist: Mr. Fredric Simms, MLS
Reference Librarian:
Kimberly D. Adams, M.A., M.S., M.L.S.
*Statistical Data Analysis:
Audrey Chang, PhD ,
Robin Howard, MA
Francois O. Tuamokumo, PhD
*These specialists provide hands-on workshops.
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42. Education/Mentoring Resources
Head of Research Education: Marina Borovok, PhD
Cue Card Reference:
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43. Educational Resources
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Educational Resources
Research Course: 9 CME/CE, 2 days ( ) Next 2011 Research Course: November 8-9, 2011 Course PP slide show is available at: (under DRP Research School)
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44. Educational Resources
Hands-on Research Preparation Course
April-December, 2011, once/month, noon-1400.
Next Class is on September 27, 2011
(session on IRB registration)
Location: Bldg. 57, ROOM 1214-B
Next Meeting Dates: 9/27, 10/13, 11/17, 12/15
This course provides participants with the practical skills required for writing a research proposal, completing research project, submitting research results to the WRNMMC Research Competition and a peer- reviewed journal in their specialty field.
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45. Educational resources (cont.)
PubMed Search Course
Developed and presented by the National Library of Medicine
2011 DATES: Tentative dates: 10/20, 12/2
TIME:
LOCATION: WRNMMC, Bldg 57, room 1214 B
COURSE GOAL
To provide guidelines for PubMed search, and teach researchers how to perform searches on their own.
REGISTRATION:
PLEASE CONTACT Ms. Ann Holman: , or via at
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46. PubMed LINKS The PubMed links are posted on the Intranet:
RCRS and Darnall Center websites
DRP website
Darnall Center Website
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47. Hands-on Educational WORKSHOPS
Workshops are offered all year long at WRNMMC on a per-request basis.
Topics:
Literature Search by Mr. Fredric Simms
Statistical Analysis by Dr. Tuamokumo, Dr. Chang,
and Ms. Howard
Please contact our specialists to schedule a workshop
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48. Protocol Outreach Program
To discuss research ideas and roadmap:
Clinician, statistician, regulatory reviewer, laboratory scientist
45 min appointments for research ideas and roadmap.
More information will be provided by Dr. Klote (Module 6), and
Dr. Bernstein (Module 7).
To schedule an appointment
please contact Ms. Dale Gregory at
, or
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49. WRNMMC-USUHS mentorship initiative
MENTORSHIP RESOURCES
WRNMMC-USUHS mentorship initiative
USUHS If you are looking for a mentor in the specific areas of research, clinical work, education, professional development, please contact mentorship representatives at USUHS, and they will help you to find a mentor from the USUHS mentorship network:
Andrew Waters, Chair of Research Committee Dr. Jennifer Rusiecki or Dr. Barbara Knollman Co-chairs of Faculty Mentoring Committee
WRNMMC If you are looking for a mentor in the specific areas of military research, please contact research mentorship representative at WRNMMC:
Marina Borovok, PhD Head of Research Education.
On the web:
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50. MENTORSHIP RESOURCES Interdepartmental Collaborative Bethesda Research Group
MISSION
Help WRNMMC to become a premier research organization in the Department of Defense.
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51. Questions?
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52. Resources IT tools: Turnitin
Turnitin is a Plagiarism Prevention Software.
Website:
Plagiarism Prevention: Instantly identifies papers containing unoriginal material.
Peer Review: Participants can review and respond to their colleagues' work online.
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53. Turnitin http://turnitin.com/static/index.php
Resources: IT tools
Turnitin
Example of report
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54. Resources: IT tools IRBNet www.irbnet.org
IRBNet is the industry leading software, a robust set of electronic tools supporting the management, submission, review and oversight of our research protocols.
IRBNet is secure, web-based, and easy to use.
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55. Collaborative E-applications
LO 4: Recognize IT tools that support research collaboration and communication from anywhere at any time.
Collaborative E-applications
Defense Connect Online (DCO) - Synchronous
Wikis - Asynchronous
Google Docs - Asynchronous
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56. Best collaborative platform AKO/DKO www.us.army.mil
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57. Virtual meeting room DCO
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58. DCO– Defense Connect Online
DCO– Defense Connect Online - provides DoD users worldwide with a second option for enterprise collaboration services.
The DCO meeting room capabilities are: the DCO Portal, webconferencing, instant messaging, screen and file sharing, whiteboard, video and audio capabilities, hosting large meetings, and more.
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59. Virtual meeting room DCO
2011 Live Training Schedule is available at:
To participate in live training:
Go to
Enter as a guest
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60. Wikis http://www.wikispaces.com/
A wiki is a website that can be edited by anyone who is granted permission.
It is simple and powerful knowledge sharing and collaboration online tool that solves problems of Document management for a Team Project Management in an enterprise.
Other advantages of wiki:
cheap or free, simple enough for non-technical employees to use.
Detailed instructions on how to create a wiki page are available at
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61. Wikis Wiki Examples: Wikipedia: http://en.wikipedia.org/wiki/Main_Page
WRNMMC ICEBERG:
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62. Wikis
Wiki at WRNMMC
ICEBERG (Interdepartmental Collaborative Bethesda Research Group)
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63. Google Docs https://www.docs.google.com
GoogleDocs is a free web-based collaborative software.  It has applications of word processors, spreadsheet and presentations that are similar to Word, Excel and PowerPoint.
Several useful functions are: autosave, revision history and rename of the files.
It allows users to create
and edit documents online
while collaborating in
real-time with other users.
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64. References:
Hulley, S. et al.(2007), Designing Clinical Research, 2nd ed. Lippincott Williams & Wilkins
On Being a Scientist: A Guide to Responsible Conduct in Research: Third Edition. (2009). Committee on Science, Engineering, and Public Policy,
National Academy of Sciences, National Academy of Engineering, and Institute of Medicine.
Goodnoe, E. (2005). How To Use Wikis For Business. The InformationWeek Business Technology Network. Retrieved March 11, 2010, from
Pfeifer, S. (March 11, 2008). Wikis and Blogs. Presented at Administrative and Instructional Uses of Technology, ED (91) lecture at Johns Hopkins University.
Riedel, C. (2008). Turnitin Integrates Plagiarism Tool into New Online Writing Service. Retrieved March 10, 2010, from
Auga, N. (2006). Developing wikis to foster web-based learning communities: an iterative approach, International Journal of Web Based Communities (IJWBC), Vol.2, No.3. Retrieved March 12, 2010, from
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65. Questions?
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66. 2011
Thank You!
My Contact Information:
Marina Borovok, PhD
Head of Research Education
Department of Research Programs
Directorate for Professional Education
Walter Reed National Military Medical Center
8901 Wisconsin Avenue,
Bldg. 1, Rm. 4372,
Bethesda, MD 20889
Phone:
Fax:
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