1. Physical map of a human chromosome
Physical map of a human chromosome. A global overview of a first-generation physical map of a human chromosome constructed by the Human Genome Project is depicted. Specifically, a yeast artificial chromosome (YAC)-based sequence-tagged site (STS)-content map of human chromosome 7 is aligned relative to the cytogenetic map (left) and genetic map (right).107 Each of the vertical bars in the middle (labeled A to V) corresponds to an individual YAC contig (see Fig for a more detailed view of a very small portion of contig O). Some of the contigs are quite large (e.g., contig E spans ≈50 Mb or ≈30 percent of the chromosome). Note that the positions of virtually all of the YAC contigs on the cytogenetic and genetic maps have been established. For additional details, see Bouffard et al. 107.
Source: The Human Genome Project and Its Impact on the Study of Human Disease, The Online Metabolic and Molecular Bases of Inherited Disease
Citation: Valle D, Beaudet AL, Vogelstein B, Kinzler KW, Antonarakis SE, Ballabio A, Gibson K, Mitchell G. The Online Metabolic and Molecular Bases of Inherited Disease; 2014 Available at: Accessed: October 09, 2017
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