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A: Population frequency histogram of urinary debrisoquine/4-hydroxydebrisoquine ratios after debrisoquine administration to 258 individuals in a healthy.

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Presentation on theme: "A: Population frequency histogram of urinary debrisoquine/4-hydroxydebrisoquine ratios after debrisoquine administration to 258 individuals in a healthy."— Presentation transcript:

1 A: Population frequency histogram of urinary debrisoquine/4-hydroxydebrisoquine ratios after debrisoquine administration to 258 individuals in a healthy British population. (From Evans et al.353 Used by permission.) B: Population frequency histogram of sparteine/dehydrosparteine ratios after sparteine administration to 735 individuals in a healthy German population. (From Eichelbaum et al.478 Used by permission.) C: Cosegregation of debrisoquine and sparteine metabolic ratios in a Canadian population. (From Inaba et al.356 Used by permission.) Source: Pharmacogenetics, The Online Metabolic and Molecular Bases of Inherited Disease Citation: Valle D, Beaudet AL, Vogelstein B, Kinzler KW, Antonarakis SE, Ballabio A, Gibson K, Mitchell G. The Online Metabolic and Molecular Bases of Inherited Disease; 2014 Available at: Accessed: October 01, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved

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