Download presentation
Presentation is loading. Please wait.
Published byPhoebe Horton Modified over 6 years ago
1
Effects of Myrtus communis extract treatment in bile duct ligated rats
Ali Sen, PhD, Sevil Ozkan, MD, Kafiye Recebova, MSc, Ozge Cevik, PhD, Feriha Ercan, PhD, Elif Kervancıoglu Demirci, MSc, Leyla Bitis, PhD, Goksel Sener, PhD Journal of Surgical Research Volume 205, Issue 2, Pages (October 2016) DOI: /j.jss Copyright © 2016 Elsevier Inc. Terms and Conditions
2
Fig. 1 (A) GSH and (B) SOD levels of the liver tissues in the control (C), MC, BDL, and BDL + MC groups. Each group consists of eight animals. *P < 0.05, **P < 0.01 compared with control group, +P < 0.05 compared with BDL group. Journal of Surgical Research , DOI: ( /j.jss ) Copyright © 2016 Elsevier Inc. Terms and Conditions
3
Fig. 2 (A) MDA levels and (B) MPO activity values of the liver tissues in the control (C), MC, BDL, and BDK + MC groups. Each group consists of eight animals. ***P < 0.001 compared with control group, ++P < 0.01, +++P < 0.001 compared with BDL group. Journal of Surgical Research , DOI: ( /j.jss ) Copyright © 2016 Elsevier Inc. Terms and Conditions
4
Fig. 3 (A) Luminol and (B) Lucigenin CL values of the liver tissues in the control (C), MC, BDL, and BDL + MC groups. Each group consists of eight animals. ***P < 0.001 compared with control group. +++P < 0.001 compared with BDL group. Journal of Surgical Research , DOI: ( /j.jss ) Copyright © 2016 Elsevier Inc. Terms and Conditions
5
Fig. 4 (A) TGF-β and (B) hydroxyproline values of the liver tissues in the control (C), MC, BDL, and BDL + MC groups. Each group consists of eight animals. ***P < 0.001 compared with control group. +P < 0.05 compared with BDL group. Journal of Surgical Research , DOI: ( /j.jss ) Copyright © 2016 Elsevier Inc. Terms and Conditions
6
Fig. 5 Normal liver parenchyma with hepatocytes, sinusoids, and portal tracts were observed in the control (A, B) and MC-treated control (C, D) groups. Disorganization of hepatic cords, increased number of degenerated hepatocytes (arrowhead), fibrosis in the form of delicate bands around the acini and bile duct proliferation within the portal tract (*), and inflammatory cell infiltration (arrow) in parenchyma. (E, F) were seen in BDL group. Mild disorganization of hepatic cords, decrease in degenerated hepatocytes (arrowhead) and inflammatory cell infiltration, moderate fibrosis around the acini, and decreased bile duct proliferation (*) were observed in BDL + MC group (G, H). (A, C, E, G) Hematoxylin and eosin staining; (B, D, F, H) Gomori's one-step trichrome staining. Original magnifications × 400. (Color version of figure is available online.) Journal of Surgical Research , DOI: ( /j.jss ) Copyright © 2016 Elsevier Inc. Terms and Conditions
Similar presentations
© 2024 SlidePlayer.com Inc.
All rights reserved.