1. Female reproductive system 1. Genital organs 2. Functions 3. Ovary 4. Uterine tube 5. Uterus 6. Vagina 7. Mammary glands 8. Embryogenesis 9. Menstrual cycle

2. 1. Internal genitalia (ovaries, uterine tube, uterus, vagina) 2. External genitalia (labia majora and minora, mons pubis, clitoris, vestibular bulbs) 3. Accessory organs (vestibular glands) 4. Mammary glands

3. Functions 1. Generative 2. Endocrine 3. Fertilization 4. Embryo and fetus development 5. Newborn nourishment

4. Ovary ( ovogenesis+endocrine)

5. Ovarial cortex (maturing follicles +atretic bodies+ corpora lutea+ corpora albicans)

6. Types of follicles

7. Primordial follicles

8. Primary follicle

10. Secondary follicle

11. Graafian follicle theca

12. Corpus luteum 1. Proliferation and vascularisation 2. Glandular metamorphosis 3. Secretion 4. Involution 5. Corpus albicans

13. Luteocytes

14. Types of luteocytes 1. Theca luteocytes 2. Granulosa luteocytes Function – synthesis of progesteron which regulates uterinal mucosa

15. Uterine tube mucosa ( epithelium+lamina propr.) muscular (O II sm. m.) serosa

16. Uterine tube (conveys oocytes, place of fertilization)

17. Uterine tube 1. Mucosa (ciliated epithelium+lamina propria) 2. Muscularis (O and II layers) 3. Serosa (peritoneum duplication) Secretory (peg) cells

18. Uterine tube epithelium

19. Uterus 1. Endometrium 2. Myometrium 3. Perimetrium 4. Parametrium Myometrium Endometrium Glands Space Epithelium Lamina propria Myometrium

20. Uterine glands

21. Endometrium layers: 1) functional (spongy and compact); 2) basal Uterine glands (crypts) - are simple tubular nonbranched glands Have neck, body and fundus Cambial cells lie in the bottom

22. Vagina

23. Mammary gland

24. Lactating mammary gland

25. Secretory process of lactating mammary gland

26. Embryonic development 1. Indifferent stage 3-6 th weeks 2-3 weeks-gonocytoblasts in yolk sack 4 week-migration to embryo 2. Different stage 8-10 w testes inhibin I 20 w rete testis inhibin II 40 w inhibin III Androgen masculinization

27. Endocrine regulation Higher center (preoptic zone)

28. Menstrual cycle Cyclic structural modifications in endometrium and other organs Menstrual 1-4 days Postmenstrual 5-14 days Premenstrual 14-28 days

29. Uterine glands

30. Vagina and endomethrium