1. Chemistry of Life Chapter #2 ST 110

2. OBJECTIVES Define Terms related to Chemical organization Describe the structure of an atom Compare and contrast ionic and covalent bonding Distinguish between organic and inorganic compounds

3. OBJECTIVES Discuss chemical characteristics of water Explain the concept of pH Discuss the structure and function of organic molecules

4. Basic Terms  Atom  Molecule  Protons  Neutrons  Electrons  Atomic Number  Atomic Mass

5. Basic Terms  Ionic bonds  Covalent bonds  Hydrolysis  Organic chemistry  Inorganic chemistry  ATP  Solute  Solvent

6. Life is Chemistry Food Digestion Food Digestion Formation of bone tissue Formation of bone tissue Contraction of muscles Contraction of muscles

7. BIOCHEMISTRY  Studying chemical aspects of life

8. Levels of Chemical Organization  Matter  Molecules  Atoms

9. ATOMS Composed of subatomic particles Protons Electrons Neutrons

10. Atoms  Nucleus  Atomic number  Atomic mass

12. Atoms  Electrons stay in certain limits called orbitals  Each orbital can hold two electrons  The closer to the nucleus, the lower the energy level

13. Orbitals The second energy level has four orbitals The second energy level has four orbitals How many electrons can be held in the second energy level? How many electrons can be held in the second energy level?

14. IMPORTANCE???? The outer number of electrons determines how the atom “behaves chemically”

15. Elements Element- pure substance of only one type of atom  Each element has a symbol Example: Hydrogen Nitrogen Potassium

16. C.O.H.N. Four atoms that make up 96% of the human body Carbon Oxygen Hydrogen Nitrogen

17. Molecules and Compounds Atoms unite with each other to form molecules. Atoms unite with each other to form molecules. Compounds have more than one element in them. Compounds have more than one element in them.

18. Compounds  The number of atoms in each molecule is expressed by a subscript Example: CO 2 = carbon dioxide one carbon, two oxygen's H 2 O 2 = hydrogen peroxide two hydrogen’s, two oxygen’s

19. Compounds/Chemical Bonding  Chemical bonds form to make atoms more stable  An atom is stable when it’s outer energy level is full  Atoms react to each other to make their outer most level full

20. Ionic Bonds Electrons are donated One atom will become negatively charged, and the other will become positively charged.

21. +++POSITIVE ION +++ an ion that has given up its electron to another atom ---NEGATIVE ION--- an ion that has borrowed an electron

22. Na-sodium – donates one electron then becomes positive IONIC BONDS Cl-chlorine- borrows one electron then it becomes negative Na + Cl = NaCl (sodium chloride)

24. IONS  Ionic molecules dissolve easily in water  Dissociate- when ionic bonds break apart  Electrolytes- are molecules that form ions when dissolved in water

25. QUESTION??????? What are the four main atoms that make up 96% of the human body?

26. QUESTION???????? What is a positive ion? What is a negative ion?

27. Covalent Bonds  Covalent Bonds  Atoms can fill their energy level by sharing electrons  Covalent bonds do not break apart in water

28. Covalent Bonding

29. Question??? What is ionic bonding?

30. Question???? What is Covalent bonding?

31. Inorganic Chemistry  Inorganic compounds do not contain Carbon-Carbon, or Carbon Hydrogen bonds  Few inorganic compounds have carbon in them  Inorganic compounds are smaller and less complex than organic compounds

32. H2OH2O Inorganic Compound Why is water considered inorganic?

33. Solvent is a substance in which other substances are dissolved. Water is a Solvent !!! Solute is a substance that dissolves into another substance. Is it a solvent, or a solute? Salt is a solute!!!

34. Mixture- a blend of two or more kinds of molecules Aqueous solution - When water is the solvent for two or more kinds of molecules

35. Dehydration Synthesis  Synthesis- Is the reaction in which two reactants combine to form a product Dehydration synthesis can only occur when a water molecule is removed from the reactants and then they bind to form a larger product.

36. Hydrolysis Water disrupts the bonds in large molecules Water disrupts the bonds in large molecules The larger molecule is broken into smaller molecules The larger molecule is broken into smaller molecules Hydrolysis is the reverse of dehydration synthesis Hydrolysis is the reverse of dehydration synthesis

37. Chemical Reactions Always Involve Energy Transfers  Some energy is stored as potential energy in the chemical bonds Ex: ATP (adenosine triphosphate)

38. Chemical Equation  Arrows – indicate direction of the chemical reaction.  Arrows going in BOTH directions simultaneous chemical reactions

39. pH Balanced ! Herbal Essence Shampoo? or something else? pH balance is 7

40. Which way does an ACID go on the pH scale???? Which numbers on the pH scale represent a base?

41. Acids are compounds that produce an excess of H+ ions Bases (alkaline) are compounds that produce an excess of OH- ions (or decreased in H+)

42. Isotopes Isotopes- two atoms with the same atomic number, but different atomic mass

43. Metric System 1 meter= 39.37 inches 1 meter= 39.37 inches 1 centimeter= 1/100 meter 1 centimeter= 1/100 meter 1 millimeter= 1/1,000 meter 1 millimeter= 1/1,000 meter I micrometer= 1/1,000,000 meter I micrometer= 1/1,000,000 meter

44. End of Day 1 Questions???

45. Organic Chemistry  Much more complex than inorganic compounds Larger than inorganic compounds

46. Organic Chemistry Four major types of organic compounds  Carbohydrates  Lipids  Proteins  Nucleic Acids

47. Carbohydrates Carbo-carbon hydrate-water  Basic unit of a carbohydrate is called monosaccharide EX: Glucose important monosaccharide  Primary source of energy

48. Carbohydrates  Disaccharide- a molecule made up of 2 saccharide units (double sugar) EX: Sucrose- table sugar Lactose- milk sugar After eaten, the body digests them to form monosaccharides to be used as cellular fuel

49. Carbohydrates  Polysaccharides- many saccharides joined together  Each glycogen molecule is a chain of glucose molecules joined together EX: glycogen and starch  Liver cells and muscles cells form glycogen. Excess glucose in blood is stored for later use.

50. Carbohydrates  Carbohydrates have potential energy stored in their bonds

51. Lipids  Lipid- fat and oils At room temperature Fats- solid lipid Oils- liquid lipid

52. Lipids Triglycerides Bonds can be broken apart to yield energy Store energy in cells for later use

53. Lipids  Phospholipids  The phosphorus containing unit in each molecule forms a head that attracts water  Two fatty acid tails repel water

54. Cholesterol  Performs several important functions in the body  Combines with phospholipids in cell membrane to stabilize bi-layer structure  Body uses cholesterol to make steroid hormones. Estrogen, testosterone, cortisone

55. Proteins  Very large molecule made of amino acids  Amino acids are held together by peptide bonds  Two types of proteins  Structural  Functional

56. Proteins  Form Structures of the body  Collagen- fibrous protein that holds many tissues together  Keratin- forms tough waterproof fibers in outer layer of the skin Structural Proteins

57. Proteins Functional Proteins  Participate in chemical processes  Hormones, cell membrane channels receptors, enzymes

58. Enzymes  Catalysts- aid in chemical reactions  Lock-and-key model  Proteins can combine with other organic molecules to form glycoproteins lipoproteins

59. Nucleic Acid DNA-deoxyribonucleic acid Master code Master code Double helix Double helix

60. Nucleic Acid RNA- ribonucleic acid  Working copy

61. Nucleic Acid  Made of nucleotide units  Sugar (ribose, or deoxyribose)  Phosphate- nitrogen based adenine, thymine or uracil, guanine cytosine

62. What are the four major types of organic compounds found in the body?

63. What is glycogen?

64. What is the primary source of energy for cells?

65. What are lipids?

66. What are proteins made of?

67. What is an enzyme?

68. What are the two types of nucleic acids?

69. What are the nitrogen bases?

70. What shape is DNA?

71. End of Day 2 Questions???