1. MEIOSIS Reproduction that occurs from recombining genetic material from two parents.

2. Reproduction Is a characteristic that all living things demonstrate … in 2 different forms: Asexual and Sexual

3. Asexual Reproduction One parent cell goes through MITOSIS in order to produce 2 daughter cells that are practically identical to the parent.

4. Mitosis looks like:

5. Sexual Reproduction Through MEIOSIS, 2 parent cells (sex cells) combine genetic material to produce offspring that have similar (but not identical) characteristics of both parents.

6. Meiosis looks like:

7. But hold on … there is a lot more to Meiosis:

8. In order for a new organism to be created, it must have the right amount of DNA (found in your chromosomes). If human sex cells had the same amount of chromosomes as all of your other cells, then when they combined together, you would make a cell with 98 chromosomes instead of 46 … and that just wouldn’t work!

9. So MEIOSIS is a process that makes sure sex cells are formed with exactly HALF the genetic material an organism needs. That way, 1 sex cell from each parent (1 sperm and 1 egg) will combine to provide the right amount of chromosomes needed! This process is similar to MITOSIS, but also very different.

10. We’ll now go through the phases of MEIOSIS:

11. Interphase G1: - The cell starts to increase in size -The cell contains 23 PAIRS of chromosomes -The chromosomes pair up to the one that carries the same types of genes … these are called HOMOLOGOUS CHROMOSOMES -Each member of a homologous chromosome pair is called a homologue, one comes from the father, and the other from the mother!

12. Interphase S: - The DNA replicates to create 2 copies of everything. -Identical copies attach together at a midpoint called a centromere. -The centriole pairs also duplicate (for animals – plants do not have centrioles).

13. Prophase I : - This is the beginning of Meiosis I -Homologous chromosomes move together and pair up, making a tetrad -Once a tetrad is formed, DNA is exchanged between the homologues in a process called Crossing Over -Crossing over is RANDOM!!! This gives us the benefit of variation!!! -Also, the chromosomes thicken and condense, the nuclear membrane fades away and the centrioles start to go to opposite sides.

14. Crossing Over

15. Metaphase I : - The tetrads are pulled to the “equator” by spindle fibers -More genetic variation occurs here as the chromosomes line up randomly, which is called INDEPENDENT ASSORTMENT -The centrioles are now in place, the nuclear membrane is gone and the spindles can be fully formed.

17. Anaphase I : - The spindle fibers attach to each homologous pair and start pulling them to opposite sides (they don’t pull apart, as in Mitosis). - The cell elongates to prepare for division.

18. Telophase I : - This is the end of the FIRST part of Meiosis -2 distinct poles are defined with one set of NON-IDENTICAL DNA on each side -The cell starts to pinch in the middle, this is the beginning of cytokinesis – which will result in 2 NON-IDENTICAL daughter cells -The DNA stretches back out again and a nuclear membrane forms, spindle fibers go away. -The centrioles will duplicate again before the next phase.

19. Prophase II: - This is the beginning of Meiosis II -This is a LOT like Mitosis, only the cells that result are not identical to the parent -Nuclear membranes dissolve -Chromosomes condense and thicken again -Centriole pairs (now there are 2 pairs in the new cells) migrate away from each other

20. Metaphase II: - Chromosomes move to the middle -This is another event (Independent Assortment) that allows for variation (the chromosomes line up randomly) -Centrioles are on opposite sides -Nuclear membrane is completely dissolved -Spindle fibers are fully formed

22. Anaphase II: - Spindle fibers attach to the chromatids and pull them apart, taking half to each pole - The cell elongates

23. Telophase II: - This is the final phase, the DNA gets long and stringy again -Nuclear membranes start to form -Spindle fibers dissolve -Cell membrane begins to pinch cell in half -In males, 4 sperm are created, in females, 1 egg and 3 polar bodies are created

24. Variation: The process of meiosis results in gametes that are all different from one another, as well as the parent cells. Variation occurs in 3 SPECIFIC events: 1.Crossing over in Prophase I 2.Independent Assortment in Metaphase I 3.Independent Assortment in Metaphase II

25. Meiosis Model: Use 2 different colors of yarn for the chromosomes. Draw everything else. Show ALL phases of Meiosis using the yarn, blank paper and pens or markers. Label each phase clearly!