1. Bellwork Draw this in your notes and fill in the phases of mitosis

2. MEIOSIS Unit 6

3. Terms to Know  Homologous Chromosomes – corresponding (matching) chromosomes from a female and male parent. -Each pair of homologous chromosomes has genes for the same traits  Diploid Cell (2n) – a cell with two of each kind of chromosome  Haploid Cell (n) – a cell that contains one set of the same kind of chromosomes  Sexual reproduction — reproduction involving the production and fusion of haploid sex cells  Gene – segment of DNA that codes for a trait  Replicated Chromosome – a chromosome that has doubled it’s DNA  Non-Replicated Chromosome – a chromosome that has split and contains only one copy of DNA.

4. What is Meiosis and why do we need it?  A form of cell division happening in sexually reproducing organisms consisting of two consecutive cell divisions (meiosis I and meiosis II).  Meiosis produces 4 haploid (n) sex cells  Sperm—male gamete  Egg—female gamete Meiosis: a kind of cell division, which produces gametes containing half the number of chromosomes as a parent’s body cell

5. Meiosis Overview  Meiosis I:  One diploid cell (46 replicated chromosomes/23 pairs) becomes two cells  Meiosis II:  The two cells become 4 haploid cells  These cells are not identical but they are very similar

6. Why half the chromosomes in gametes?  At fertilization the male and female sex cells will provide ½ of the chromosomes each – so the offspring has genes from both parents

7. Fertilization  The haploid sperm (carrying 1 set of chromosomes) combines with the haploid egg (carrying 1 set of chromosomes). The result is a diploid zygote.

8. Female vs. Male Oogenesis egg production Spermatogenesis Sperm Production

9. What does Meiosis accomplish? 1. Meiosis takes a cell with two copies of every chromosome (diploid) and makes cells with a single copy of every chromosome (haploid). 2. Meiosis scrambles the specific forms of each gene that each sex cell (egg or sperm) receives through crossing over and independent assortment.

10. Steps in Meiosis  PMAT 2 similar cells 23 chromosomes Separates homologous pairs Haploid  PMAT 4 similar cells 23 chromosomes Separates replicated chromosomes Haploid Meiosis I – starts diploidMeiosis II – starts haploid Same steps as Mitosis, divides twice to produce 4 daughter cells instead of 2. Daughter cells are not identical but similar

11. Interphase  Interphase  Cells duplicate their DNA  G1, S, G2

12. Prophase I  Prophase I  sister chromatids pair up forming a homologous chromosome  Crossing Over:  When two chromosomes exchange portions of their chromatids (genetic material is swapped)  Synapsis: the homologous chromosomes line up forming a four part structure called a tetrad. Crossing over during meiosis, increases the genetic variability due to allele combinations. – Genetic recombination is a major source of variation among organisms

13. Metaphase I  Metaphase I  Spindle fibers attach to the centromeres on each chromosome  Homologous chromosomes line up together.

14. Anaphase I  Anaphase I Spindle fibers pull the homologous chromosomes toward opposite ends of the cell.

15. Telophase I/Cytokinesis  Telophase I/Cytokinesis Meiosis I results in 2 haploid (n) daughter cells. Each with half the number of chromosomes as the original cell (23) Still replicated chromosomes.

16. Prophase II  Prophase II 2 haploid (n) daughter cells. Each with half the number of chromosomes as the original cell. Interphase does NOT happen again. Same steps as normal prophase.

17. Metaphase II  Metaphase II The chromosomes line up in a similar way to the metaphase stage of mitosis. Occurs in BOTH cells.

18. Anaphase II  Anaphase II The sister chromatids separate and move toward opposite ends of the cell

19. Telophase II / Cytokinesis  Telophase II / Cytokinesis Opposite of prophase occurs, cytoplasm splits. END RESULT: four haploid (n), non-replicated, non- identical daughter cells.

20. Mitosis vs. Meiosis  Diploid 2n  diploid 2n  46 chromosomes  46 chromosomes  Replicated chromosomes  Non-Replicated Chromosomes  Somatic Cells  Creates 2 identical cells  1 trip through PMAT  Diploid 2n  haploid n  46 chromosomes  23 chromosomes  Replicated chromosomes  Non-Replicated Chromosomes  Gamete cells  Creates 4 similar cells  2 trips through PMAT

21. Meiosis Drawing  Things to Label:  Label each cell as diploid (2n) or haploid (n)  Label the chromosome number of each cell  Circle and label a homologous pair of chromosomes  Circle and label a replicated chromosome.  Circle and label a non-replicated chromosome.