1. Lesson Sequence 1. 2. 3. 4. Genetic Crosses 5. 6. 7. 8. 9. 10.

2. Resources needed: Genetic crosses Harry Potter worksheet. (1 per student) Info sheet for teacher Req: none

3. PLTS icons if needed

4. Genetic crosses Wednesday, 06 January 2016 Level ObjectiveOutcome E/D Explain how recessive and dominant genes interact Complete the starter successfully C/B Interpret and draw punnet squares and family trees. Complete of 1 & 2 of Harry Potter tasks. Slides 19- 23 A- A* Consider the ethical issues of genetic counselling. Answer question on slide 31 and page Keywords Dominant, recessive, punnet square, family tree. carrier Starter: Charlie has Hazel eyes. Her parents both have blue eyes. Draw a diagram to EXPLAIN how this can be Extension: miércoles, 06 de enero de 2016 mercredi 6 janvier 2016 Explain why you have some features that are similar to your siblings. Use the word allele in your answer.

5. Genetic crosses Wednesday, 06 January 2016 Keywords Dominant, recessive, punnet square, family tree. carrier Extension: miércoles, 06 de enero de 2016 mercredi 6 janvier 2016 Explain why you have some features that are similar to your siblings. Use the word allele in your answer. We need some definitions: match the correct word to the definition: DominantCarrier RecessiveGenotype Phenotype RR Rr rr What you look like Your genetic make up

6. Genetic crosses Wednesday, 06 January 2016 Keywords Dominant, recessive, punnet square, family tree. carrier Extension: miércoles, 06 de enero de 2016 mercredi 6 janvier 2016 Explain why you have some features that are similar to your siblings. Use the word allele in your answer. We need some definitions: match the correct word to the definition: DominantCarrier RecessiveGenotype Phenotype RR Rrrr What you look like Your genetic make up

7. Genetic crosses Wednesday, 06 January 2016 Keywords Dominant, recessive, punnet square, family tree. carrier Extension: miércoles, 06 de enero de 2016 mercredi 6 janvier 2016 Explain why you have some features that are similar to your siblings. Use the word allele in your answer. Naked Scientist animation! (from interactive book)

8. How are characteristics inherited? I don’t understand why she is a Witch if her parents are muggles? I don’t understand why she is a Witch if her parents are muggles? No wonder, Malfoy! You didn’t pay attention in my genetics lessons!!!

9. Inheritance of characteristics I still don’t understand why she is a witch… I still don’t understand why she is a witch… But it’s easy!!! Let me explain some Wizard Genetics to you

10. How are Wizards made? It’s all in their genes!!!! It’s all in their genes!!!! The allele for being a Wizard is m The allele for being a muggle is M The allele for being a muggle is M Being a muggle is dominant over being a Wizard….. Being a muggle is dominant over being a Wizard….. Like muggles, Wizards inherit one allele from their mum, and one allele from their dad Like muggles, Wizards inherit one allele from their mum, and one allele from their dad Let’s do some Wizard genetics… Let’s do some Wizard genetics…

11. Wizards and muggles… The allele for being a Wizard is ……… The allele for being a muggle is ……… Being a muggle is ……………………… over being a Wizard Let’s do some Wizard genetics… Let’s do some Wizard genetics…

12. Answer the questions on Wizard genetics on your worksheets.... Wizards and muggles… Let’s do some Wizard genetics… Let’s do some Wizard genetics…

13. The Potters - What alleles do Harry’s parents have? - What were the chances of Harry being a Wizard?

14. Harry’s grandparents Harry’s grandparents Lily Potter Petunia Dursley Harry’s grandmother Harry’s granddad - What alleles do Lily’s parents have? - What were the chances of Lily being a witch? - What were the chances of Petunia being a muggle? - What are the chances that Petunia is a “carrier”?

15. The Dursleys Petunia Vernon Even if Petunia was a carrier of the Wizarding allele, is there any chance at all that Dudley was a Wizard? What are his odds at best (given his father is not a Wizard?

16. The Malfoys

17. The Grangers Why is Hermione a witch? What were the chances?

18. Tom Riddle Tom Riddle was a half-blood. His mother was a witch and his father was a muggle. What alleles did his parents have? What were the chances that Tom Riddle was a wizard?

19. Hermione + Ron Will their children definitively be Wizards and Witches?

20. Argus Filch is a squib. His parents were Wizards, but doesn’t really have any wizarding abilities. Suggest an explanation. Filch

21. Speaking Parseltongue is a rare feature in the Wizarding world. Only descendents from Slytherin might have this ability. Harry speaks Parseltongue, but Ginny doesn’t and neither did Harry’s parents. Suggest if the allele for speaking Parseltongue is dominant or recessive: What are the chances that Harry’s and Ginny’s children speak Parseltongue if (a) Ginny isn’t a carrier and (b) if Ginny does carry the allele? Harry + Ginny Harry + Ginny (a)(b)

22. (c) Actually, Harry didn’t inherit the two recessive Parseltongue alleles, but they were transferred to his DNA when Voldemort tried to kill him. What is the scientific name for this process? Harry + Voldemort Harry + Voldemort

23. (a) Being werewolf (W) is dominant over not being a werewolf (w). Remus Lupin is a werewolf (Ww), but his wife, Nymphadora Tonks, is not. What are the chances that their son is a werewolf? Remus

24. (b) Both Remus and Nymphadora also carry the allele for speaking Parseltongue. What are the chances that their son is a werewolf who speaks Parseltongue? Remus

25. Genetic crosses Level ObjectiveOutcome E/D Explain how recessive and dominant genes interact Complete the starter successfully C/B Interpret and draw punnet squares and family trees. Complete of 1 & 2 of Harry Potter tasks. Slides 19- 23 A- A* Consider the ethical issues of genetic counselling. Answer question on slide 31 and page MID-LESSON PROGRESS CHECK Swap work with the person next to you. Are they on track to meet their target?

26. Family trees

27. Family tree Family tree genetic diagrams are used by doctors to provide genetic counselling for couples with genetic disorders prior to pregnancy. Q. Explain why they are useful and what ethical considerations such counselling might raise.

28. Plenary: What have you learnt today? Next lesson: Inherited Disorders 5 mins Plenary task Level ObjectiveOutcome E/D Explain how recessive and dominant genes interact Complete the starter successfully C/B Interpret and draw punnet squares and family trees. Complete of 1 & 2 of Harry Potter tasks. Slides 19- 23 A- A* Consider the ethical issues of genetic counselling. Answer question on slide 31 and page Write one thing you know well this lesson and one thing you need to improve on.