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The origin of post-injury neointimal cells in the rat balloon injury model by Luis Rodriguez-Menocal, Melissa St-Pierre, Yuntao Wei, Sheik Khan, Dania.

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Presentation on theme: "The origin of post-injury neointimal cells in the rat balloon injury model by Luis Rodriguez-Menocal, Melissa St-Pierre, Yuntao Wei, Sheik Khan, Dania."— Presentation transcript:

1 The origin of post-injury neointimal cells in the rat balloon injury model by Luis Rodriguez-Menocal, Melissa St-Pierre, Yuntao Wei, Sheik Khan, Dania Mateu, Marian Calfa, Amir A. Rahnemai-Azar, Gary Striker, Si M. Pham, and Roberto I. Vazquez-Padron Cardiovasc Res Volume 81(1):46-53 January 1, 2009 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

2 Assessment of GFP transgene expression in rat iliac arteries by immunofluorescence and confocal microscopy. Luis Rodriguez-Menocal et al. Cardiovasc Res 2009;81:46- 53 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

3 Post injury neointimal cells are of local origin in the rat balloon-injury model. Luis Rodriguez-Menocal et al. Cardiovasc Res 2009;81:46- 53 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

4 Inflammatory cells involved in the arterial response to balloon-injury are of BM origin. Luis Rodriguez-Menocal et al. Cardiovasc Res 2009;81:46- 53 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

5 Neointimal cells of aortic isografts are of donor origin. Luis Rodriguez-Menocal et al. Cardiovasc Res 2009;81:46- 53 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

6 Vascular smooth muscle cells migrated through the media to the neointima in response to vascular injury. Luis Rodriguez-Menocal et al. Cardiovasc Res 2009;81:46- 53 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2008. For permissions please email: journals.permissions@oxfordjournals.org

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