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Substrate and Trigger Ablation for Reduction of Atrial Fibrillation (STAR AF): a randomized, multicentre, international trial by Atul Verma, Roberto Mantovan,

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Presentation on theme: "Substrate and Trigger Ablation for Reduction of Atrial Fibrillation (STAR AF): a randomized, multicentre, international trial by Atul Verma, Roberto Mantovan,"— Presentation transcript:

1 Substrate and Trigger Ablation for Reduction of Atrial Fibrillation (STAR AF): a randomized, multicentre, international trial by Atul Verma, Roberto Mantovan, Laurent Macle, Guiseppe De Martino, Jian Chen, Carlos A. Morillo, Paul Novak, Vittorio Calzolari, Peter G. Guerra, Girish Nair, Esteban G. Torrecilla, and Yaariv Khaykin EHJ Volume 31(11):1344-1356 June 1, 2010 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2010. For permissions please email: journals.permissions@oxfordjournals.org

2 Study patient randomization flowchart. Atul Verma et al. Eur Heart J 2010;31:1344-1356 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2010. For permissions please email: journals.permissions@oxfordjournals.org

3 (A–C) Representative left atrial (LA) electroanatomical maps illustrating the three ablation strategies used in the study. Atul Verma et al. Eur Heart J 2010;31:1344-1356 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2010. For permissions please email: journals.permissions@oxfordjournals.org

4 (A and B) Kaplan–Meier curves depicting time to first atrial fibrillation (AF) recurrence (A) and time to first AF, atrial flutter (AFL), or atrial tachycardia (AT) recurrence (B) after one procedure in the pulmonary vein isolation (PVI) strategy, the complex fractionated electrogram (CFE) strategy, and the combined strategy of PVI followed by CFE ablation (PVI + CFE). Atul Verma et al. Eur Heart J 2010;31:1344-1356 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2010. For permissions please email: journals.permissions@oxfordjournals.org

5 (A and B) Kaplan–Meier curves depicting time to first atrial fibrillation (AF) recurrence (A) and time to first AF, atrial flutter (AFL), or atrial tachycardia (AT) recurrence (B) after two procedures in the pulmonary vein isolation (PVI) strategy, the complex fractionated electrogram (CFE) strategy, and the combined strategy of PVI followed by CFE ablation (PVI + CFE). Atul Verma et al. Eur Heart J 2010;31:1344-1356 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2010. For permissions please email: journals.permissions@oxfordjournals.org

6 Percentage of patients free from either atrial fibrillation (AF) or AF, atrial flutter (AFL) or atrial tachycardia (AT) in the high-burden paroxysmal and persistent subgroups after one procedure. Atul Verma et al. Eur Heart J 2010;31:1344-1356 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2010. For permissions please email: journals.permissions@oxfordjournals.org

7 Percentage of patients undergoing repeat ablation procedures in each of the three arms of the study. Atul Verma et al. Eur Heart J 2010;31:1344-1356 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2010. For permissions please email: journals.permissions@oxfordjournals.org

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