1. Chapter 16 – The Endocrine System $100 $200 $300 $400 $500 $100$100$100 $200 $300 $400 $500 Endocrinology 1, 2, 3 Pituitary Power! Peter Pan “creas” Moan for a Hormone Name that Gland FINAL ROUND

2. Endocrinology 1, 2, 3: $100 Question Which of these characteristics is exclusive to the endocrine system, when compared with the nervous system? a. Relies on release of chemical that bind to specific receptors b. Relies primarily on negative feedback mechanisms c. Uses epinephrine and norepinephrine as chemical messengers d. Effective in coordinating cell, tissue, and organ activities on a sustained, long-term basis BACK TO GAME ANSWER

3. Endocrinology 1, 2, 3: $100 Answer Which of these characteristics is exclusive to the endocrine system, when compared with the nervous system? a. Relies on release of chemical that bind to specific receptors b. Relies primarily on negative feedback mechanisms c. Uses epinephrine and norepinephrine as chemical messengers d. Effective in coordinating cell, tissue, and organ activities on a sustained, long-term basis BACK TO GAME

4. Endocrinology 1, 2, 3: $200 Question How does the hypothalamus regulate nervous and endocrine activities? a. It secretes regulatory hormones that influence endocrine cells in the pituitary. b. It has autonomic centers that exert direct neural control over endocrine cells of the adrenal medullae. c. Hypothalamic neurons synthesize hormone and transport them along axons within the infundibulum d. All of these are correct. BACK TO GAME ANSWER

5. Endocrinology 1, 2, 3: $200 Answer How does the hypothalamus regulate nervous and endocrine activities? a. It secretes regulatory hormones that influence endocrine cells in the pituitary. b. It has autonomic centers that exert direct neural control over endocrine cells of the adrenal medullae. c. Hypothalamic neurons synthesize hormone and transport them along axons within the infundibulum d. All of these are correct. BACK TO GAME

6. Endocrinology 1, 2, 3: $300 Question Which of the following statements is true of peptide hormones? a. They are derived from cholesterol. b. They are synthesized as prohormones and convert to active hormones before or after secretion. c. They are also called biogenic amines and are synthesized from tyrosine. d. They are important paracrine factors that coordinate cellular activities. BACK TO GAME ANSWER

7. Endocrinology 1, 2, 3: $300 Answer Which of the following statements is true of peptide hormones? a. They are derived from cholesterol. b. They are synthesized as prohormones and convert to active hormones before or after secretion. c. They are also called biogenic amines and are synthesized from tyrosine. d. They are important paracrine factors that coordinate cellular activities. BACK TO GAME

8. Endocrinology 1, 2, 3: $400 Question If levels of a certain hormone are high, which of the following will happen? a. A second messenger brings more of that hormone into the cell. b. There will be a decrease in the number of cell receptors for that hormone and cells become less sensitive to it. c. A G protein will bind to that hormone. d. There will be an increase in the number of cell receptors for that hormone and cells become more sensitive to it. BACK TO GAME ANSWER

9. Endocrinology 1, 2, 3: $400 Answer If levels of a certain hormone are high, which of the following will happen? a. A second messenger brings more of that hormone into the cell. b. There will be a decrease in the number of cell receptors for that hormone and cells become less sensitive to it. c. A G protein will bind to that hormone. d. There will be an increase in the number of cell receptors for that hormone and cells become more sensitive to it. BACK TO GAME

10. Endocrinology 1, 2, 3: $500 Question How does the presence of a molecule that blocks adenylate cyclase affect the activity of a hormone that produces its cellular effects by way of the second messenger cAMP? a. It prevents synthesis of the hormone. b. It enhances the action of the hormone. c. It increases sensitivity to the hormone. d. It decreases speed of hormonal changes. BACK TO GAME ANSWER

11. Endocrinology 1, 2, 3: $500 Answer How does the presence of a molecule that blocks adenylate cyclase affect the activity of a hormone that produces its cellular effects by way of the second messenger cAMP? a. It prevents synthesis of the hormone. b. It enhances the action of the hormone. c. It increases sensitivity to the hormone. d. It decreases speed of hormonal changes. BACK TO GAME

12. Pituitary Power!: $100 Question What is critically important about the vascular arrangement of the hypophyseal portal system? a. It provides efficient means of ensuring that all hypothalamic hormones will reach target cells in the adenohypophysis before being diluted in general circulation. b. It ensures that all hormones destined for the pituitary are diluted in general circulation before entering the adenohypophysis. c. It ensures that RH from the hypothalamus synthesizes the correct amount of a specific hormone. d. None of these is correct. BACK TO GAME ANSWER

13. Pituitary Power!: $100 Answer What is critically important about the vascular arrangement of the hypophyseal portal system? a. It provides efficient means of ensuring that all hypothalamic hormones will reach target cells in the adenohypophysis before being diluted in general circulation. b. It ensures that all hormones destined for the pituitary are diluted in general circulation before entering the adenohypophysis. c. It ensures that RH from the hypothalamus synthesizes the correct amount of a specific hormone. d. None of these is correct. BACK TO GAME

14. Pituitary Power!: $200 Question What is the role of FSH in males? a. It stimulates production of sex hormones. b. It stimulates the breakdown of stored triglycerides by adipocytes. c. It stimulates sustenacular cells, which then promotes maturation of sperm. d. It stimulates smooth muscle contraction in the ductus deferens and prostate gland. BACK TO GAME ANSWER

15. Pituitary Power!: $200 Answer What is the role of FSH in males? a. It stimulates production of sex hormones. b. It stimulates the breakdown of stored triglycerides by adipocytes. c. It stimulates sustenacular cells, which then promotes maturation of sperm. d. It stimulates smooth muscle contraction in the ductus deferens and prostate gland. BACK TO GAME

16. Pituitary Power!: $300 Question If a person has been drinking alcohol, how is ADH released by the neurohypophysis affected? a. More ADH is released to increase the solute concentration of blood and urine. b. ADH secretion is inhibited by drinking alcohol. c. It does not change at all. d. ADH secretion increases causes vasoconstriction and increased blood pressure. BACK TO GAME ANSWER

17. Pituitary Power!: $300 Answer If a person has been drinking alcohol, how is ADH released by the neurohypophysis affected? a. More ADH is released to increase the solute concentration of blood and urine. b. ADH secretion is inhibited by drinking alcohol. c. It does not change at all. d. ADH secretion increases causes vasoconstriction and increased blood pressure. BACK TO GAME

18. Pituitary Power!: $400 Question A blood sample shows elevated levels of somatomedins. Which pituitary hormone will be elevated as well? a. Thyroid stimulating hormone b. Growth hormone c. Oxytocin d. Adrenocorticotropic hormone BACK TO GAME ANSWER

19. Pituitary Power!: $400 Answer A blood sample shows elevated levels of somatomedins. Which pituitary hormone will be elevated as well? a. Thyroid stimulating hormone b. Growth hormone c. Oxytocin d. Adrenocorticotropic hormone BACK TO GAME

20. Pituitary Power!: $500 Question Why do high levels of cortisol, a steroid hormone from the suprarenal cortex, cause a decrease in the pituitary secretion of ACTH? a. Because high levels of cortisol stimulated other steroid hormones. b. The hormones act in a synergistic manner. c. Because ACTH participates in a negative feedback loop with cortisol. d. CRH from the hypothalamus inhibits ACTH release. BACK TO GAME ANSWER

21. Pituitary Power!: $500 Answer Why do high levels of cortisol, a steroid hormone from the suprarenal cortex, cause a decrease in the pituitary secretion of ACTH? a. Because high levels of cortisol stimulated other steroid hormones. b. The hormones act in a synergistic manner. c. Because ACTH participates in a negative feedback loop with cortisol. d. CRH from the hypothalamus inhibits ACTH release. BACK TO GAME

22. Peter Pan “creas”: $100 Question Which pancreatic cell type is paired with the hormone it produces? a. Alpha cells / pancreatic polypeptide b. F cells / a hormone identical to growth hormone- inhibiting hormone c. Beta cells / insulin d. Delta cells / glucagon BACK TO GAME ANSWER

23. Peter Pan “creas”: $100 Answer Which pancreatic cell type is paired with the hormone it produces? a. Alpha cells / pancreatic polypeptide b. F cells / a hormone identical to growth hormone- inhibiting hormone c. Beta cells / insulin d. Delta cells / glucagon BACK TO GAME

24. Peter Pan “creas”: $200 Question Insulin lowers the level of glucose in the blood, and then glucagon causes glucose levels to rise. What is this type of hormonal interaction called? a. Synergistic b. Permissive c. Antagonistic d. Integrative BACK TO GAME ANSWER

25. Peter Pan “creas”: $200 Answer Insulin lowers the level of glucose in the blood, and then glucagon causes glucose levels to rise. What is this type of hormonal interaction called? a. Synergistic b. Permissive c. Antagonistic d. Integrative BACK TO GAME

26. Peter Pan “creas”: $300 Question Which of the following is an affect of glucagon? a. Accelerated glucose uptake and utilization b. Breakdown of triglycerides in adipose tissue c. Stimulation of amino acid absorption and protein synthesis d. Stimulation of glycogen formation BACK TO GAME ANSWER

27. Peter Pan “creas”: $300 Answer Which of the following is an affect of glucagon? a. Accelerated glucose uptake and utilization b. Breakdown of triglycerides in adipose tissue c. Stimulation of amino acid absorption and protein synthesis d. Stimulation of glycogen formation BACK TO GAME

28. Peter Pan “creas”: $400 Question Cells in the ___ are insulin independent, which means that they can ____. a. Brain, kidneys, and digestive tract / absorb glucose without insulin stimulation b. Liver / produce glucose c. Pancreas and suprarenal cortex / produces insulin d. Suprarenal cortex and suprarenal medulla / function without insulin BACK TO GAME ANSWER

29. Peter Pan “creas”: $400 Answer Cells in the ___ are insulin independent, which means that they can ____. a. Brain, kidneys, and digestive tract / absorb glucose without insulin stimulation b. Liver / produce glucose c. Pancreas and suprarenal cortex / produces insulin d. Suprarenal cortex and suprarenal medulla / function without insulin BACK TO GAME

30. Peter Pan “creas”: $500 Question Why are diabetics continuously thirsty and why do they frequently urinate? a. Less water is reclaimed by osmosis in the kidneys. b. Water loss reduces blood volume, promoting secretion of ADH. c. Glucose is lost in the urine, which increases blood volume. d. A and B are correct. BACK TO GAME ANSWER

31. Peter Pan “creas”: $500 Answer Why are diabetics continuously thirsty and why do they frequently urinate? a. Less water is reclaimed by osmosis in the kidneys. b. Water loss reduces blood volume, promoting secretion of ADH. c. Glucose is lost in the urine, which increases blood volume. d. A and B are correct. BACK TO GAME

32. Moan for a Hormone: $100 Question Increased amounts of sunlight inhibit the production of which hormone? a. Prolactin b. Melanocyte stimulation hormone c. Aldosterone d. Melatonin BACK TO GAME ANSWER

33. Moan for a Hormone: $100 Answer Increased amounts of sunlight inhibit the production of which hormone? a. Prolactin b. Melanocyte stimulation hormone c. Aldosterone d. Melatonin BACK TO GAME

34. Moan for a Hormone: $200 Question Iodine deficiency in the diet produces what symptom? a. Increased rate of metabolism b. Increased body temperature c. Exaggerated response to physiological stress d. Goiter BACK TO GAME ANSWER

35. Moan for a Hormone: $200 Answer Iodine deficiency in the diet produces what symptom? a. Increased rate of metabolism b. Increased body temperature c. Exaggerated response to physiological stress d. Goiter BACK TO GAME

36. Moan for a Hormone: $300 Question Deficiencies of which hormones impede normal skeletal development? a. GH, thyroid hormone, PTH, and reproductive hormones b. Prolactin, FSH, LH, GH c. Thyroid hormone, melatonin, PTH, calcitonin d. GH, TSH, ACTH, FSH BACK TO GAME ANSWER

37. Moan for a Hormone: $300 Answer Deficiencies of which hormones impede normal skeletal development? a. GH, thyroid hormone, PTH, and reproductive hormones b. Prolactin, FSH, LH, GH c. Thyroid hormone, melatonin, PTH, calcitonin d. GH, TSH, ACTH, FSH BACK TO GAME

38. Moan for a Hormone: $400 Question What is the effect of renin secretion by the kidneys ? a. Stimulation of Ca 2+ and PO 4 absorption along the digestive tract b. Stimulates the production of red blood cells by bone marrow c. Converts angiotensinogen to angiotensin I d. Inhibits secretion of ADH and aldosterone BACK TO GAME ANSWER

39. Moan for a Hormone: $400 Answer What is the effect of renin secretion by the kidneys ? a. Stimulation of Ca 2+ and PO 4 absorption along the digestive tract b. Stimulates the production of red blood cells by bone marrow c. Converts angiotensinogen to angiotensin I d. Inhibits secretion of ADH and aldosterone BACK TO GAME

40. Moan for a Hormone: $500 Question All of the following except ___ occur during the resistance phase of the general adaptation syndrome. a. Conservation of glucose for neural tissues b. Mobilization of remaining lipid and protein reserves c. Conservation of Na + and loss of K + and H + d. Increased mental alertness and increased blood pressure BACK TO GAME ANSWER

41. Moan for a Hormone: $500 Answer All of the following except ___ occur during the resistance phase of the general adaptation syndrome. a. Conservation of glucose for neural tissues b. Mobilization of remaining lipid and protein reserves c. Conservation of Na + and loss of K + and H + d. Increased mental alertness and increased blood pressure BACK TO GAME

42. Name that Gland: $100 Question Which of the following is not an effect of thyroid hormones on major organ systems? a. Increased heart rate and force of contraction b. Increased sensitivity to sympathetic stimulation c. Decreased turnover of minerals in bone d. Stimulation of red blood cell formation BACK TO GAME ANSWER

43. Name that Gland: $100 Answer Which of the following is not an effect of thyroid hormones on major organ systems? a. Increased heart rate and force of contraction b. Increased sensitivity to sympathetic stimulation c. Decreased turnover of minerals in bone d. Stimulation of red blood cell formation BACK TO GAME

44. Name that Gland: $200 Question The removal of the parathyroid glands result in a decrease in the blood concentration of which important mineral? a. Calcium ions b. Phosphate ions c. Sodium ions d. Potassium ions BACK TO GAME ANSWER

45. Name that Gland: $200 Answer The removal of the parathyroid glands result in a decrease in the blood concentration of which important mineral? a. Calcium ions b. Phosphate ions c. Sodium ions d. Potassium ions BACK TO GAME

46. Name that Gland: $300 Question Failure of the zona glomerulosa to secrete aldosterone would result in ____. a. Decreased formation and secretion of calcitrol b. Enhanced reabsorption of Ca 2+ at the kidneys c. Loss of Na +, K + retention, and decreased reabsorption of water at the kidneys d. None of these is correct. BACK TO GAME ANSWER

47. Name that Gland: $300 Answer Failure of the zona glomerulosa to secrete aldosterone would result in ____. a. Decreased formation and secretion of calcitrol b. Enhanced reabsorption of Ca 2+ at the kidneys c. Loss of Na +, K + retention, and decreased reabsorption of water at the kidneys d. None of these is correct. BACK TO GAME

48. Name that Gland: $400 Question Secretion of cortisol by the zona fasciculata ____ in the liver and has a(n) _____ effect on CRH in the hypothalamus? a. Decreases glucose synthesis / stimulatory b. Increases glucose synthesis / inhibitory c. Increases androgen production / antagonistic d. Decreases glycogen synthesis / synergistic BACK TO GAME ANSWER

49. Name that Gland: $400 Answer Secretion of cortisol by the zona fasciculata ____ in the liver and has a(n) _____ effect on CRH in the hypothalamus? a. Decreases glucose synthesis / stimulatory b. Increases glucose synthesis / inhibitory c. Increases androgen production / antagonistic d. Decreases glycogen synthesis / synergistic BACK TO GAME

50. Name that Gland: $500 Question Melatonin is well known for its role in regulating circadian rhythm. What are two other functions of melatonin? a. Promotes muscle mass and supports libido in females b. Testicular feminization and gynecomastia in males c. Inhibits reproductive functions and protects CNS neurons from free radicals d. Promotes early puberty and increased rates of oxygen consumption BACK TO GAME ANSWER

51. Name that Gland: $500 Answer Melatonin is well known for its role in regulating circadian rhythm. What are two other functions of melatonin? a. Promotes muscle mass and supports libido in females b. Testicular feminization and gynecomastia in males c. Inhibiting reproductive functions and protecting CNS neurons from free radicals d. Promoting early puberty and increasing rates of oxygen consumption BACK TO GAME

52. FINAL ROUND Question In what ways are hormonal effects of E and NE from the suprarenal medulla similar to the effects of glucocorticoids from the zona fasciculata? a. Hormones from both are under the ultimate control of the sympathetic nervous system. b. Both increase cardiac activity and blood pressure. c. Both are stimulated by angiotensin II. d. Both increase blood glucose levels and promote the breakdown of stored fats into fatty acids. BACK TO GAME ANSWER

53. FINAL ROUND Answer In what ways are hormonal effects of E and NE from the suprarenal medulla similar to the effects of glucocorticoids from the zona fasciculata? a. Hormones from both are under the ultimate control of the sympathetic nervous system. b. Both increase cardiac activity and blood pressure. c. Both are stimulated by angiotensin II. d. Both increase blood glucose levels and promote the breakdown of stored fats into fatty acids. BACK TO GAME