1. 2016 ASH Overview

2. Editorial With an impact factor of 10.452 (2014), and an Immediacy Index of 2.415 (2014), Blood is the most cited peer-reviewed publication in the field of hematology. The journal covers all aspects of hematology, including disorders of leukocytes, both benign and malignant, erythrocytes, platelets, hemostatic mechanisms, vascular biology, immunology, and hematologic oncology. Published weekly 51 Pint Issues 1 Digital Abstracts Issue in November

3. Circulation Print Circulation Profile Hematology/Oncology4,051 Hematology1,362 Oncology 691 Pediatric (Hem, Hem/Onc & Onc)1,259 Transfusion Medicine189 Pathology 479 Research 679 Residents1,248 Other ( Institutions, Libraries, Pharmacology ) 857 TOTAL 10,932 Bonus Distribution IssueMeetingDateLocation May 12 & 19American Society of Clinical Oncology (ASCO)Jun 3-7Chicago May 19European Hematology Association(EHA)Jun 9-12Copenhagen Sep 1ASH Hematologic MalignanciesSep 15-17Chicago, Il Nov 10 & 24American Society of Hematology (ASH)Dec 3-6TBD

4. 2016 Print Rates & Incentives Black and White Rates1x6x12x24x36x48x60x72x84x96x page $ 3,150 $ 3,050 $ 2,950 $ 2,875 $ 2,800 $ 2,700 $ 2,675 $ 2,650 $ 2,600 $ 2,550 1/2 page $ 1,700 $ 1,650 $ 1,600 $ 1,550 $ 1,525 $ 1,500 $ 1,475 $ 1,450 $ 1,425 $ 1,400 1/4 page $ 1,075 $ 1,050 $ 1,025 $ 1,000 $ 975 $ 950 $ 925 $ 900 $ 875 $ 850 Color ChargesPosition Charges 4 color $ 2,350Cover 450% 2 color standard $ 900Cover 235% 2 color matched $ 950Table of Contents25% Other25% Monthly Continuity Program Place 3 insertions for in the same month and receive the 4 th issue free All ads must be for one product, run in the same month, and be a full page or larger 6 Insertion Incentive For every 6 paid insertions get the 7 th insertion free Clinical Trials Ad Discount Clinical trials recruitment and awareness ads receive the (96x rate) All new print ads must be reviewed by the Blood Editor-in-Chief. Incentive programs are earned by individual campaigns for brands, corporate and disease awareness.

5. 70 th Anniversary Big Splash at ASH 2015 Weekly articles looking back at milestones in hematology Monthly features with KOLs Interviews and analysis with past and present Blood Editor- in-chiefs and ASH Presidents.

6. Readership Kantar - Hem/Onc June 2015 (Syndicated) #2 APEX #4 Average Issue Readers #4 Average Page Exposure Kantar Hematology June 2015 (Custom) #1 Average Issue Readers 30.5% more readers than NEJM (#2) #1 Average Page Exposure 2,999 more exposures monthly than NEJM (#2)

7. High Impact Ad Units Your Brands Message on the Front Cover! New Launches and Indications Events and Resources Reinforce brand and messaging Competitive Pricing Covertips = $16,500 net Outserts = $17,500 net

8. www.bloodjournal.org EU Monthly Metrics 153,000 Visits (33K UK) 534K impressions monthly (114K UK) CPM = $90 Average CTR = 0.05% Ad Units (728x90), (160x600) & (300x250) File Format – Flash, GIF, JPG, HTML Rich Media on Approval Max File Size – 30K

9. Blood/ASH Alerts 19,144 Opt-in Subscribers. Monthly Sponsorship 76-80,000 e-mails monthly Blood e-TOC: 4-5 drops Blood TOC Awareness: 4-5 drops Blood First Edition: 16-22 drops Blood Announcements ~68,000 impressions monthly 0.07% CTR 3 Positions (33% SOV) Top leaderboard $5,000 net Skyscraper $5,000 net Lower Leaderboard $3,000 net Sponsorship first-come basis. NO GEOTARGETING AVILABLE

10. Blood App Ave Unique Users p/m US Only 600 (15%) Ex US 3400 (85%) Global users Sept 4240 Ave sessions p/m US Only 3100 Ex US 17,900 (UK 842) Ave useage time 2 min.

11. Blood App Engaged Users 100% Registered Users 100% Viewability 1.26% Overall CTR Interstitials (25% SOV) 11.3% CTR Tablets: 1024x768 & 768x1024 Smartphone: 320x480 & 480x320 Banners (25% SOV) 728x90, 300x250 & 320x50

12. Blood App Advertising opportunities Banner advertisement 25% SOV $50K (c.£30.5K) Annually C. £2500 per month. Interstitial advertisement 25% SOV $25K (c.£15K) Annually C. £1265 per month Global/US Only/EU Only