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Cardiovascular System Pathology
Medical Terminology Chapter 5
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Atheroma ather/o = plaque -oma = tumor Plaque within the arterial wall
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Atherosclerosis athero = fatty plaque sclerosis = abnormal hardening
Hardening & narrowing of arteries due to a buildup of cholesterol plaque
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Angina pectoris Severe episodes of spasmodic choking chest pain
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Ischemia Deficiency of blood supply due to constriction or obstruction of blood vessels
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Infarct Localized area of necrosis caused by an interruption of blood supply
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Myocardial infarction (MI)
Heart attack Closing off of a coronary artery resulting in an infarct of the affected myocardium
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Coronary artery disease (CAD)
Atherosclerosis of coronary arteries that may cause angina, myocardial infarction & sudden death End-stage CAD: final phase with severe angina & severely limited lifestyle
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Congestive heart failure (CHF)
Heart is unable to pump enough blood to meet the body’s needs; leads to fluid accumulation in legs, lungs
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Forms of Carditis Endocarditis: inflammation of the inner layer of the heart Bacterial endocarditis: inflammation of the lining or valves of heart caused by bacteria Myocarditis: inflammation of the myocardium Pericarditis: inflammation of the pericardium
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Valvulitis valvul/o = valve -itis = inflammation
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Mitral valve prolapse Protrusion of the mitral valve thus incomplete closure of the valve
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Mitral stenosis Abnormal narrowing of the mitral valve also tricuspid
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Arrhythmia or dysrhythmia
Irregular rhythm of the heart
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Bradycardia brady = slow card = heart -ia = abnormal condition
Abnormally slow heartbeat
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Flutter Atrial contractions are rapid but regular
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Tachycardia tachy = fast card = heart -ia = abnormal condition
Abnormally fast heart rate
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Paroxysmal tachycardia
Sudden onset of fast heartbeat
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Fibrillation Rapid, random, & ineffective heart contractions
Atrial fibrillation (A-fib): atria faster than ventricles Ventricular fibrillation (V-fib): fatal unless reversed by electric defibrillation
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Angi/o = vessel Angiitis or vasculitis Angionecrosis Angiospasm
Angiostenosis
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Hemangioma hemangi/o = blood vessel -oma = tumor
benign tumor of blood vessels
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Hypoperfusion Deficiency of blood passing through an organ or body part
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Aneurysm Localized balloon like enlargement of the wall of an artery
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Arter/o, arteri/o = artery
Arteritis Polyarteritis Arteriosclerosis
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Raynaud’s phenomenon Intermittent attacks of pallor, cyanosis, & redness of fingers & toes secondary to arterial contraction & caused by cold or emotion
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Phlebitis phleb/o = vein -itis = inflammation Inflammation of a vein
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Varicose veins Abnormally swollen veins usually occurring in the legs
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Thrombus & Embolus Thrombus: blood clot attached to wall of a vein or artery Embolus: foreign object, such as blood clot or tissue, that is circulating in blood stream
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Thrombotic occlusion Blocking of an artery by a clot
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Coronary thrombosis Damage to the heart caused by a thrombus blocking a coronary artery
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Embolism Blockage of a vessel by an embolus
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Hemochromatosis (iron overload disease)
Hem/o = blood Chromat/o = color -osis = abnormal condition Genetic disorder in which intestines absorb too much iron
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Septicemia (blood poisoning)
Presence of pathogenic microorganisms or their toxins in the blood
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Cholesterol Lipids that travel in the blood stream as lipoproteins
Low density lipoprotein (LDL): bad cholesterol; excess contribute to plaque buildup HDL: good cholesterol
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-penia = deficiency of Leukopenia Thrombocytopenia
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Erythrocytosis erythr/o = red cyt/o = cell -osis = abnormal condition
Abnormal increase in number of RBCs
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Leukemia leuk/o = white -emia = blood condition
Malignancy with progressive increase of abnormal leukocytes
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Anemia an- = without or less than -emia = blood condition
Lower than normal numbers of RBCs
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Aplastic anemia Absence of all formed blood elements due to failure of blood cell production in bone marrow
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Hemolytic anemia hem/o = blood -lytic = to destroy
Blood cells destroyed faster than bone marrow can replace them
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Megaloblastic anemia Bone marrow produces large abnormal RBCs with a reduced ability to transport oxygen; usually from a vitamin deficiency
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Pernicious anemia RBCs are abnormally formed due to an inability to absorb Vitamin B12
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Sickle cell anemia Genetic disorder that causes abnormal hemoglobin & RBCs have a sickle shape
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Hypertension=high blood pressure
Essential or primary hypertension: unknown cause Secondary hypertension: caused by a different medical problem such as kidney disease Malignant hypertension: sudden onset of severely elevated blood pressure
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