1. Warm up! An enzyme is what kind of macromolecule?

2. Warm up #2
What do you want to do when you leave high school?

3. Proteins that catalyzes chemical reactions for organisms
Enzymes
Proteins that catalyzes chemical reactions for organisms

4. Proteins – a review What are some functions of proteins?
What is the monomer of a protein?
What is the structure of a protein?
What does –ase mean? (Latin and Greek!)
The order of amino acids is important! Consider this:
Grandma and I ate dinner for my birthday.
And for my birthday dinner I ate grandma.

5. Which graph shows less energy being used?
What lowers the energy needed?

6. Examples of enzymes Cleaners Cheesemaking
Proteases, lipases, carbohyrases…

7. Enzymes do what jobs in our bodies?
Enzymes are more important than food, water, or air!
Why?
Without enzymes, you wouldn’t be able to breathe or use the water you drink or food you eat.
Digest our food
Help make new cells
Maintain/repair tissues (skin, bones, muscle, etc)

8. Enzymes as protein robots
Very specific
Do not react with the substrates
Do their job over and over again

9. How do enzymes work?

10. How do Enzymes Work?
A substrate(s) fits into the active site on the enzyme.
The enzyme lowers the energy required to complete the reaction.
The product no longer fits the binding site and is released.

11. Another model Induced fit model Active site is reshaped each
Time a molecule binds

12. Each enzyme is specific to a single reaction
Lock and key model

13. Enzyme vocabulary Enzymes: Protein catalysts found in living things
Catalyst: decreases the energy needed to start a reaction
Reactions: a change in chemical structure
Denature: A change in the shape of an enzyme that makes it useless. The substrate no longer “fits” into the active site.
Specific: Each enzyme does a certain job
Substrate: Each enzyme binds to a specific reactant, or substrate
Active site: Where the substrate fits into the enzyme
Products: What the substrate becomes AFTER it interacts with an enzyme

14. toothpickase What did your hands represent?
What did the whole toothpick represent?
Where was the active site?
What did the broken toothpick represent?

15. How fast can enzymes work?
Think about toothpickase, what affected how fast the enzyme could work?
Temperature
Competition with inhibitors
Concentration (amount in a certain area)
Of enzyme
Of substrate pH

16. Competitive Inhibition
What would happen if something else binds with the enzyme?
The is competition.

17. Denatured Enzyme
What happens when something changes the shape of the Enzyme?
The substrate no longer “fits” into its’ Active Site.
The “key” is the same, but the “lock” has been changed.
What would this do to your body and its energy?

18. Do enzymes build or Take apart?
AND
Take Apart
Build

19. Properties of enzymes Made of proteins Speed up reactions Are specific
NOT used up during the reaction
Require specific conditions to work
They become denatured when they are at high temperatures or the wrong pH
Reduce the energy needed for a reaction

21. Pair/share
Can you describe
What is happening
Here?

22. All enzymes work best at a neutral pH
True or false?
All enzymes work best at a neutral pH

23. The names of all enzymes end in -ase
True or false?
The names of all enzymes end in -ase

24. Enzymes are packaged and sold in stores
True or false?
Enzymes are packaged and sold in stores

25. Brain cells contain enzymes
True or false?
Brain cells contain enzymes

26. Cooked food is made of cells and therefore contains enzymes.
True or false?
Cooked food is made of cells and therefore contains enzymes.

27. TRUE OR FALSE?
The enzymes in cooked food work the same way as enzymes in raw food.

28. All cells contain the same enzymes
True or false
All cells contain the same enzymes

29. The human body has an estimated 75,000 different enzymes
True or false
The human body has an estimated 75,000 different enzymes

30. True or false
Enzymes are “used up” during a reaction

31. Single celled organisms have enzymes
True or false
Single celled organisms have enzymes

32. True or false
Enzymes are living things