1. HEART PHYSIOLOGY and HEART DISORDERS

2. The Electrocardiogram The conduction of APs through the heart generates electrical currents that can be read through the skin AP = Action Potential Currents picked up by electrodes The recording is called an ELECTROCARDIOGRAM (ECG or EKG)

3. The Electrocardiogram, cont. Each heartbeat produces three clearly recognizable waves. The P wave, the QRS Complex, and the T wave

4. The Electrocardiogram, cont. P Wave A small upward deflection The P wave represents the AP as it spreads throughout the Atria A second after the P wave begins, the atria contract

5. The Electrocardiogram, cont. QRS Complex QRS complex occurs as the AP spreads through the ventricles After the QRS complex begins, the ventricles contract

6. The Electrocardiogram, cont. T Wave Upward deflection that occurs just before the ventricles relax

7. The Cardiac Cycle A single Cardiac Cycle includes all events associated with one heartbeat The two atria contract while the two ventricles relax; ventricles contract while atria relax

8. The Cardiac Cycle, cont. Systole refers to the phase of contraction Diastole refers to the phase of relaxation

9. HEART DISORDERS

10. 1. Pericarditis Inflammation of the pericardium (the membrane that surrounds and protects the heart) In one form of pericarditis, there is a build up of pericardial fluid (fluid that prevents friction between layers of the pericardium) Too much fluid build-up in the pericardium will compress the heart Symptoms of pericarditis include low blood pressure and difficulty breathing

11. 1. Pericarditis

12. 2. Heart Murmur A heart murmur is an abnormal sound consisting of a clicking, rushing, or gurgling noise that is heart before, between, or after the normal heart sounds A heart murmur could mask the normal heart sounds Heart murmurs are very common in children and are usually outgrown In adults, the heart disorders could indicate a valve disorder

13. Stenosis Stenosis = Narrowing of a heart valve opening that restricts blood flow The failure of a valve to close completely is termed insufficiency or incompetence

14. 3. Mitral Stenosis Scar formation from an infection or a congenital defect causes narrowing of the mitral valve

15. 4. Mitral Valve Prolapse In MVP, one or both cusps of the mitral (bicuspid) valve protrude into the left atrium during ventricular contraction Backflow of flood from the left ventricle into the left atrium

16. 5. Aortic Stenosis The aortic valve is narrowed A backflow of blood from the aorta into the left ventricle Valves must be repaired or replaced by human or pig donors or by artificial valves

17. 6. Artificial Pacemaker When the heart rate is too low, an artificial pacemaker can restore normal heart rhythm Sends out small electrical currents to stimulate the heart to contract Pacemaker wires are threaded through the superior vena cava and placed on the right atrium and right ventricle Pace makers are implanted beneath the skin inferior to the clavicle

18. 7. Congestive Heart Failure In congestive heart failure (CHF), the heart begins to fail Pumps less and less effectively, leaving blood in the ventricles after every cycle PULMONARY EDEMA - If the left ventricle fails first, the heart cannot pump out all the blood it receives and blood backs up in the lungs. Can lead to suffocation. PERIPHERAL EDEMA – The right ventricle fails firsts, and blood backs up in systemic blood vessels. First noticeable as swelling in the feet and ankles.

19. 8. Atherosclerosis A progressive disease characterized by the formation in the walls of large and medium of lesions called atherosclerotic plaques Two proteins are monitored in cholesterols for this disease are LDL and HDL LDL (low-density lipoprotein) and HDL (high-density lipoprotein) HDL removes cholesterols – is known as “good cholesterol” The HDL should be high and the LDL should be low

20. 9. Myocardial Infarction A complete obstruction to blood flow in a coronary artery Myocardial Infarction (MI) = Heart Attack 10. Cardiac Arrest A clinical term meaning cessation of an effective heartbeat The heart may be completely stopped or in ventricular fibrillation (spontaneous contractions of individual muscle fibers)

21. 11. Cardiomegaly An enlarged heart

22. 12. Tachycardia Faster (than normal) heart rate at rest 13. Bradycardia Slower (than normal) resting heart rate

23. 14. Rheumatic Fever A streptococcal infection of the throat that affects the bicuspid (mitral) and aortic valves in the heart Bacterial infection triggers immune response that inflames damages the tissues – can weaken entire heart