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Leukemia By Mary Chen and Genesis Pimentel

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1 Leukemia By Mary Chen and Genesis Pimentel

2 Website  

3 What is leukemia?  Cancer of the blood  Begins in bone marrow  If healthy, makes white blood cells, red blood cells, and platelets  In a leukemia patient, unregulated growth of immature “leukemia” cells crowds out normal cells  Enters bloodstream  liver, spleen, lymph nodes  4 Major types:  Acute Myelogenous Leukemia (AML)  Acute Lymphoblastic Leukemia (ALL)  Chronic Myelogenous Leukemia (CML)  Chronic Lymphocytic Leukemia (CLL). Abnormal leukemia cells

4 Types of Leukemia  Acute or chronic = how fast the cancer progresses  Acute immediate effects  Chronic gradual and may not show symptoms for years  Myelogenous or Lymphocytic/lymphoblastic depends on type of white blood cell it affects (lymphocytes or myelocytes)  Acute lymphoblastic leukemia: most common childhood cancer  Chronic lymphocytic leukemia: most common in adults, especially those older than 55; rare in children  Acute myelogenous leukemia: both children and adults  Chronic myelogenous leukemia: mainly in adults

5 Risk Factors  Genetics  Such as chromosomal abnormalities like down syndrome  Family history  Exposure to Dangerous Chemicals  formaldehyde and benzene  Exposure to High Levels of Radiation  Medical radiation like frequent X-rays  Nuclear fallout  Prior history of chemotherapy  Lifestyle factors  Smoking/drug abuse correlate with higher chances of developing leukemia (especially myelogenous leukemia),,

6 Symptoms, Detection, & Diagnosis  Common Symptoms  Detection & Diagnosis  physical exam  Swollen lymph nodes/spleen?  Paleness?  blood tests  bone marrow biopsy

7 Treatment  Depends on age, overall health, stage of cancer, type of cancer, and consideration of side effects  “remission” not “cure”  Chemotherapy: anti-cancer drugs to kill leukemia cells  Surgery: to remove enlarged spleen/cancerous areas  Radiation: high-dose X-rays to treat cancer cells that may stay after surgery  Bone Marrow Transplants: can rebuild a patient's supply of normal blood cells and boost their immune system  radiation or chemotherapy first to destroy the cells in the patient's bone marrow to make room for the donated cells  Biological Therapy: improve the body's natural defenses against cancer  Clinical Trials: studies to test new medicines and other possible treatments, There are side effects for certain treatments. Chemotherapy causes temporary hair loss.

8 5-Year Survival Rate  National Cancer Institute Surveillance Epidemiology and End Results Review 2010 Estimate  43,050 new cases will be diagnosed in US; 21,840 will die  Overall 5-year relative survival from 17 different geographic areas was 54.1%  Breakdown by race and gender  54.6% for white males, 54.2% for white females  46.8% for black males, 46.2% for black females.  In US, estimated middle age of death for leukemia is 74 years

9 Interesting Facts  History  Greeks first recognized the disease in the 5th century  "leukemia" comes from Greek "leukos" + "hemia" = white blood  John Hughes Benett made the first diagnosis in 1845, Edinburgh  The disease  affects more men than women but men have a slightly higher survival rate  chronic is more common among older people while acute is mainly pediatric

10 Famous People With Leukemia  Ed Bradley Marie Curie Mary Travers Bill Walsh,,

11 Works Cited  Davis, Bets. "Leukemia - Symptoms, Types, Causes, Diagnoisis and Treatment Options for Leukemia." WebMD. Healthwise, 26 Nov. 2008. Web. 12 Oct. 2010.. overview  "Facts About Leukemia." Cancer Prevention. 2010. Web. 13 Oct. 2010..http://www.your-cancer-prevention-  "Famous People With Leukemia." HistoryKing. History King, 2010. Web. 16 Oct. 2010..  Feist, Patty. "Signs of Childhood Cancer." Pediatric Oncology Resource Center. Association of Cancer Online Resources, July 2005. Web. 12 Oct. 2010..>.  Leukemia." MayoClinic. Mayo Foundation for Medical Education and Research, 3 Apr. 2010. Web. 13 Oct. 2010..  "Leukemia Home Page." National Cancer Institute. National Cancer Institute, 2010. Web. 11 Oct. 2010..  "Leukemia Risk Factors." Oncology Channel. 04 Dec. 2007. Web. 12 Oct. 2010..  Myrrh, Hector. "Leukemia 101." The New York Times Company, 8 May 2010. Web. 12 Oct. 2010..

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